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Job DescriptionQ03526
Confidence100.00%DateWed Jul 10 14:09:50 BST 2013
Rank235Aligned Residues255
% Identity37%Templatec2xbaA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429
Resolution1.95 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   361........370......... 380.........390.........400..... ....410....
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Query Sequence  WVIQPSELTFVQEIGSGQF. . . . GLVHLGYWLNKDKVAIKTIQEGAMSE. . EDFIEEAEV
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Template Sequence  FAGKTSSISDLKEVPRKNITLIRGLVYEGQV. SPLQVAVKTLPEVCSEQDELDFLMEALI
Template Known Secondary structure  TT
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   1098.1100.........1110.........1120........ .1130.........1140.........1150......
 
   415....420.........430.........440.........450....... ..460........
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Query Sequence  MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRG. . . . . . LFAAETLLGMC
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Template Sequence  ISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVA
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   1171........1180.........1190.........1200.........1210.........1220.........1230
 
   469470.........480.........490.........500.........510.........520........
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Query Sequence  LDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVK
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Template Sequence  RDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMA. . . . . . RDIYAMLPVK
Template Known Secondary structure  TT


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   1231........1240.........1250.........1260.........1270.... .....1280....
 
   529530.........540.........550.........560.........570.........580........
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Query Sequence  WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLA
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Template Sequence  WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC
Template Known Secondary structure  G

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   1295....1300.........1310.........1320.........1330.........1340.........1350....
 
   589590.........600.........610.........620..
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Query Sequence  SCHVYQIMNHCWKEKPEDRPPFSQLLSQLAEIAE
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Template Sequence  PGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQ
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   1355....1360.........1370.........1380........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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