Job Description Q03526 Confidence 100.00% Date Wed Jul 10 14:09:50 BST 2013 Rank 134 Aligned Residues 239 % Identity 22% Template c2r7bA_ PDB info PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor Resolution 2.70 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.		.	390	.	.	.	.	.	.	.	.	.					400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.
Predicted Secondary structure																											.												.	.	.	.
Query SS confidence																											.												.	.	.	.
Query Sequence		Q	P	S	E	L	T	F	V	Q	E	I	G	S	G	Q	F	G	L	V	H	L	G	Y	W	L	.	N	K	D	K	V	A	I	K	T	I	Q	.	.	.	.	E	G	A	M	S	E	E	D	F	I	E	E	A	E	V	M	M	K	L
Query Conservation																											.												.	.	.	.
Alig confidence																											.												.	.	.	.
Template Conservation
Template Sequence		R	P	E	D	F	K	F	G	K	I	L	G	E	G	S	F	S	T	V	V	L	A	R	E	L	A	T	S	R	E	Y	A	I	K	I	L	E	K	R	H	I	I	K	E	N	K	V	P	Y	V	T	R	E	R	D	V	M	S	R	L
Template Known Secondary structure			G	G	G											S	S									T	T	T																	T	T														T
Template Predicted Secondary structure
Template SS confidence
		78	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.
		419	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	H	P	K	L	V	Q	L	Y	G	V	C	L	E	Q	A	P	I	C	L	V	F	E	F	M	E	H	G	C	L	S	D	Y	L	R	S	Q	R	G	L	F	A	A	E	T	L	L	G	M	C	L	D	V	C	E	G	M	A	Y	L
Query Conservation
Alig confidence																																									.
Template Conservation																																									.
Template Sequence		D	H	P	F	F	V	K	L	Y	F	T	F	Q	D	D	E	K	L	Y	F	G	L	S	Y	A	K	N	G	E	L	L	K	Y	I	R	K	I	G	S	.	F	D	E	T	C	T	R	F	Y	T	A	E	I	V	S	A	L	E	Y	L
Template Known Secondary structure				T	T	B										S	S										T	T		B								S	S	S	.
Template Predicted Secondary structure																																									.
Template SS confidence
		138	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.		.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.
		479	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	K	A	C	V	I	H	R	D	L	A	A	R	N	C	L	V	G	E	N	Q	V	I	K	V	S	D	F	G	M	T	R	F	V	L	D	D	Q	Y	T	S	S	T	G	T	K	F	P	V	K	W	A	S	P	E	V	F	S	F	S
Query Conservation
Alig confidence																																				.	.	.	.	.	.	.	.	.	.
Template Conservation																																				.	.	.	.	.	.	.	.	.	.
Template Sequence		H	G	K	G	I	I	H	R	D	L	K	P	E	N	I	L	L	N	E	D	M	H	I	Q	I	T	D	F	G	T	A	K	V	L	.	.	.	.	.	.	.	.	.	.	F	V	G	T	A	Q	Y	V	S	P	E	L	L	T	E	K
Template Known Secondary structure				T	T								T	T	T					T	T	S								T	T					.	.	.	.	.	.	.	.	.	.					G	G	G								S	S
Template Predicted Secondary structure																																				.	.	.	.	.	.	.	.	.	.
Template SS confidence
		197	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230											.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.
		539	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	S	E	G	K	I	P	Y	E	N	R	S	N	S	E	V	V	E	D	I	S	T	G	F	R	L	Y	K	P	R	L	A	S	C	H	V	Y	Q	I	M	N	H
Query Conservation
Alig confidence																						.																						.
Template Conservation																						.																						.
Template Sequence		S	A	C	K	S	S	D	L	W	A	L	G	C	I	I	Y	Q	L	V	A	.	G	L	P	P	F	R	A	G	N	E	Y	L	I	F	Q	K	I	I	K	L	E	.	Y	D	F	P	E	K	F	F	P	K	A	R	D	L	V	E	K
Template Known Secondary structure																						.	S	S		S				S	S											T		.					S	S	S										T
Template Predicted Secondary structure																						.																						.
Template SS confidence
		258	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.		.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.		.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
		599	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	W	K	E	K	P	E	D	R	P	P	F	S	Q	L	L	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	L	V	L	D	A	T	K	R	L	G	C	E	E	M	E	G
Template Known Secondary structure		T	S		S	S	T	T	S	S	T	T	S	G	G	G	T	T
Template Predicted Secondary structure
Template SS confidence
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D