Job Description Q03526 Confidence 100.00% Date Wed Jul 10 14:09:50 BST 2013 Rank 6 Aligned Residues 419 % Identity 38% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:73.901 Y:75.143 Z:52.039

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		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.		220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																									.
Query SS confidence																																									.
Query Sequence		L	V	I	A	L	Y	D	Y	Q	T	N	D	P	Q	E	L	A	L	R	C	D	E	E	Y	Y	L	L	D	S	S	E	I	H	W	W	R	V	Q	D	.	K	N	G	H	E	G	Y	A	P	S	S	Y	L	V	E	K	S	P	N	N
Query Conservation																																									.
Alig confidence																															.										.																		.	.
Template Conservation																															.																												.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	.	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	.	.	S
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T									.		T	T							T	T	T								G	G	G				T	T	.	.	S
Template Predicted Secondary structure																															.																												.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.		90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.			.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.		.	.	.	.	.	270	.	.	.	.	.		.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.
Predicted Secondary structure																											.												.
Query SS confidence																											.												.
Query Sequence		L	E	T	Y	E	W	Y	N	K	S	I	S	R	D	K	A	E	K	L	L	L	D	T	G	K	.	E	G	A	F	M	V	R	D	S	R	T	.	P	G	T	Y	T	V	S	V	F	T	K	A	I	I	S	E	N	P	C	I	K	H
Query Conservation																											.												.
Alig confidence																											.												.												.
Template Conservation																																																			.
Template Sequence		L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	.	D	P	R	Q	G	D	T	V	K	H
Template Known Secondary structure		G	G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T										.		T	T	T
Template Predicted Secondary structure																																																			.
Template SS confidence
		118	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.		.	.	.	170	.	.	.	.	.	.
		298	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	H	I	K	E	T	N	D	S	P	K	R	Y	Y	V	A	E	K	Y	V	F	D	S	I	P	L	L	I	Q	Y	H	Q	Y	N	G	G	G	L	V	T	R	L	R	Y	P	V	C	S	W	R	Q	K	A	P	V	T	A	G	L	R
Query Conservation
Alig confidence												.	.																																											.	.	.	.
Template Conservation												.	.																																											.	.	.	.
Template Sequence		Y	K	I	R	T	L	D	N	G	G	.	.	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	.	.	.	.	W	E
Template Known Secondary structure					B			S	T	T		.	.			S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B										.	.	.	.
Template Predicted Secondary structure												.	.																																											.	.	.	.
Template SS confidence
		177	.	.	180	.	.	.	.	.	.			.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.					.	230
		358	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	G	K	W	V	I	Q	P	S	E	L	T	F	V	Q	E	I	G	S	G	Q	F	G	L	V	H	L	G	Y	W	L	N	K	D	K	V	A	I	K	T	I	Q	E	G	A	M	S	E	E	D	F	I	E	E	A	E	V	M	M	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T
Template Known Secondary structure		T	T		S	B			G	G	G											T	T									T	T	T												S	S														T
Template Predicted Secondary structure
Template SS confidence
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
		418	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.		.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.
Predicted Secondary structure																																											.
Query SS confidence																																											.
Query Sequence		L	S	H	P	K	L	V	Q	L	Y	G	V	C	L	E	Q	A	P	I	C	L	V	F	E	F	M	E	H	G	C	L	S	D	Y	L	R	S	Q	R	G	L	.	F	A	A	E	T	L	L	G	M	C	L	D	V	C	E	G	M	A
Query Conservation																																											.
Alig confidence															.																												.
Template Conservation															.
Template Sequence		L	Q	H	D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A
Template Known Secondary structure					T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G
Template Predicted Secondary structure															.
Template SS confidence
		291	.	.	.	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.
		477	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	L	E	K	A	C	V	I	H	R	D	L	A	A	R	N	C	L	V	G	E	N	Q	V	I	K	V	S	D	F	G	M	T	R	F	V	L	D	D	Q	Y	T	S	S	T	G	T	K	F	P	V	K	W	A	S	P	E	V	F	S
Query Conservation
Alig confidence																																				.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																				.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N
Template Known Secondary structure						T	T				S			S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S
Template Predicted Secondary structure																																				.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.
		537	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	S	R	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	S	E	G	K	I	P	Y	E	N	R	S	N	S	E	V	V	E	D	I	S	T	G	F	R	L	Y	K	P	R	L	A	S	C	H	V	Y	Q	I	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M
Template Known Secondary structure																							T	T	T			S	S	T	T												T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
		597	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	H	C	W	K	E	K	P	E	D	R	P	P	F	S	Q	L	L	S	Q	L	A	E	I	A	E	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A
Template Known Secondary structure					T		S	S	G	G	G	S												T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.