|   |   |
359 | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | |
390 | . | . | . | . | . | . | . | . | . | |
|
|
|
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | K | W | V | I | Q | P | S | E | L | T | F | V | Q | E | I | G | S | G | Q | F | G | L | V | H | L | G | Y | W | L | N | . |
K | D | K | V | A | I | K | T | I | Q | . |
. |
. |
. |
E | G | A | M | S | E | E | D | F | I | E | E | A | E |
| Query Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   | . |   |   |   |
|
|
|
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| Template Sequence |   |
E | R | Q | P | V | T | K | N | T | F | R | Q | Y | R | V | L | G | K | G | G | F | G | E | V | C | A | C | Q | V | R | A | T | G | K | M | Y | A | C | K | K | L | E | K | K | R | I | K | K | R | K | G | E | A | M | A | L | N | E | K | Q |
| Template Known Secondary structure |   |
 | T | S |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
177 | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
|   |
|   |   |
414 | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | M | M | K | L | S | H | P | K | L | V | Q | L | Y | G | V | C | L | E | Q | A | P | I | C | L | V | F | E | F | M | E | H | G | C | L | S | D | Y | L | R | S | Q | R | G | L | F | A | A | E | T | L | L | G | M | C | L | D | V | C | E |
| Query Conservation |   |
  |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   | . |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |
| Template Sequence |   |
I | L | E | K | V | N | S | R | F | V | V | S | L | A | Y | A | Y | E | T | K | D | A | L | C | L | V | L | T | L | M | N | G | G | D | L | K | F | H | I | Y | H | M | A | G | . |
F | P | E | A | R | A | V | F | Y | A | A | E | I | C | C |
| Template Known Secondary structure |   |
 |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |
|
|
|
| S |
| B |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | |
. | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . |
|   |
|   |   |
474 | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | M | A | Y | L | E | K | A | C | V | I | H | R | D | L | A | A | R | N | C | L | V | G | E | N | Q | V | I | K | V | S | D | F | G | M | T | R | F | V | L | D | D | Q | Y | T | S | S | T | G | T | K | F | P | V | K | W | A | S | P | E |
| Query Conservation |   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |
|
|   |   |
|   |
|
|
|
| Template Sequence |   |
G | L | E | D | L | H | R | E | R | I | V | Y | R | D | L | K | P | E | N | I | L | L | D | D | H | G | H | I | R | I | S | D | L | G | L | A | V | H | V | P | E | G | Q | T | I | K | G | R | . |
. |
V | G | T | V | G | Y | M | A | P | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |
|
| T | T |
|
|  |  |
|
| . | . |
| S |
| G | G | G |
|
|  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
|
. | . | . | . | 350 | . | . | . | . | . |
|   |
|   |   |
534 | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | F | S | F | S | R | Y | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | V | F | S | E | G | K | I | P | Y | E | N | R | S | N | S | E | V | V | E | D | I | S | T | G | F | R | L | Y | K | P | R | L | A | S | C | H | V | Y |
| Query Conservation |   |
  |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Template Sequence |   |
V | V | K | N | E | R | Y | T | F | S | P | D | W | W | A | L | G | C | L | L | Y | E | M | I | A | . |
G | Q | S | P | F | Q | Q | K | I | K | R | E | E | V | E | R | L | V | K | E | V | P | E | E | Y | S | E | R | F | S | P | Q | A | R |
| Template Known Secondary structure |   |
 |  | T | T |
|  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| T | T | S |
|  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
356 | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | |
. | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . |
|   |
|   |   |
594 | . | . | . | . | . | 600 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 610 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
| . | . | . | . | . |
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | I | M | N | H | C | W | K | E | K | P | E | D | R | . |
. |
. |
. |
. |
P | P | F | S | Q | L | L | S |
| Query Conservation |   |
  |
|
|   |   |
|   |   |   |
|
|   |   |
| . | . | . | . | . |
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |
|   |   |
|   |   |
| Template Sequence |   |
S | L | C | S | Q | L | L | C | K | D | P | A | E | R | L | G | C | R | G | G | S | A | R | E | V | K | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  | S |
| S | S | G | G | G | S | T | T | S | S | S | S | T |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
418 | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . |
|   |