Job Description Q03526 Confidence 100.00% Date Wed Jul 10 14:09:50 BST 2013 Rank 2 Aligned Residues 435 % Identity 38% Template c1y57A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor Resolution 1.91 Å Model Dimensions (Å) X:72.506 Y:93.275 Z:44.514

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		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.		220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Predicted Secondary structure																																										.
Query SS confidence																																										.
Query Sequence		T	L	V	I	A	L	Y	D	Y	Q	T	N	D	P	Q	E	L	A	L	R	C	D	E	E	Y	Y	L	L	D	S	S	E	I	H	W	W	R	V	Q	D	.	K	N	G	H	E	G	Y	A	P	S	S	Y	L	V	E	K	S	P	N
Query Conservation																																										.
Alig confidence																																										.																.	.
Template Conservation																																																										.	.
Template Sequence		T	T	F	V	A	L	Y	D	Y	E	S	R	T	E	T	D	L	S	F	K	K	G	E	R	L	Q	I	V	N	N	T	E	G	D	W	W	L	A	H	S	L	S	T	G	Q	T	G	Y	I	P	S	N	Y	V	A	P	.	.	S	D
Template Known Secondary structure		T					S	S		B				S	S	S	B			B		T	T						S			S	S	S	S							T	T	T								G	G	G				.	.	T	T
Template Predicted Secondary structure																																																										.	.
Template SS confidence
		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.			140	.
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.		.	.	.	.	.	270	.	.	.	.	.		.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure																												.												.
Query SS confidence																												.												.
Query Sequence		N	L	E	T	Y	E	W	Y	N	K	S	I	S	R	D	K	A	E	K	L	L	L	D	T	G	K	.	E	G	A	F	M	V	R	D	S	R	T	.	P	G	T	Y	T	V	S	V	F	T	K	A	I	I	S	E	N	P	C	I	K
Query Conservation																												.												.
Alig confidence																												.												.													.
Template Conservation																																																					.
Template Sequence		S	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	.	N	A	K	G	L	N	V	K
Template Known Secondary structure		S	G	G	G	S	T	T				S											T		T	T			T	T								S	S	S	T	T											.	T	T	T
Template Predicted Secondary structure																																																					.
Template SS confidence
		142	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.		.	.	.	.	.	.	.	200
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	Y	H	I	K	E	T	N	D	S	P	K	R	Y	Y	V	A	E	K	Y	V	F	D	S	I	P	L	L	I	Q	Y	H	Q	Y	N	G	G	G	L	V	T	R	L	R	Y	P	V	C	S	W	R	Q	K	A	P	V	T	A	G	L
Query Conservation
Alig confidence													.	.																																					.	.	.
Template Conservation													.	.																																					.	.	.
Template Sequence		H	Y	K	I	R	K	L	D	S	G	G	.	.	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	T	.	.	.	S	K	P	Q	T	Q	G	L
Template Known Secondary structure									S	S	S		.	.			S	S	T	T	S			S	S													T	T	S	S	S					B				.	.	.						S	S
Template Predicted Secondary structure													.	.																																					.	.	.
Template SS confidence
		201	.	.	.	.	.	.	.	.	210	.			.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.				.	.	250	.	.	.	.	.
		357	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Y	G	K	W	V	I	Q	P	S	E	L	T	F	V	Q	E	I	G	S	G	Q	F	G	L	V	H	L	G	Y	W	L	N	K	D	K	V	A	I	K	T	I	Q	E	G	A	M	S	E	E	D	F	I	E	E	A	E	V	M	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q	V	M	K
Template Known Secondary structure					T	T	B			G	G	G											T	T									T	T	T										T	T	S	S
Template Predicted Secondary structure
Template SS confidence
		256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
		417	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.		.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
Predicted Secondary structure																																												.
Query SS confidence																																												.
Query Sequence		K	L	S	H	P	K	L	V	Q	L	Y	G	V	C	L	E	Q	A	P	I	C	L	V	F	E	F	M	E	H	G	C	L	S	D	Y	L	R	S	Q	R	G	L	.	F	A	A	E	T	L	L	G	M	C	L	D	V	C	E	G	M
Query Conservation																																												.
Alig confidence																	.																											.
Template Conservation																	.
Template Sequence		K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G	M
Template Known Secondary structure						T	T	B									.	S	S	S									T	T									S
Template Predicted Secondary structure																	.
Template SS confidence
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.
		476	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	Y	L	E	K	A	C	V	I	H	R	D	L	A	A	R	N	C	L	V	G	E	N	Q	V	I	K	V	S	D	F	G	M	T	R	F	V	L	D	D	Q	Y	T	S	S	T	G	T	K	F	P	V	K	W	A	S	P	E	V	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A
Template Known Secondary structure							T	T				S			S	G	G	G					G	G	G								T	T						S	S						T	T	T	T		S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		375	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.
		536	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	F	S	R	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	S	E	G	K	I	P	Y	E	N	R	S	N	S	E	V	V	E	D	I	S	T	G	F	R	L	Y	K	P	R	L	A	S	C	H	V	Y	Q	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L
Template Known Secondary structure																								T	T	S			S	S	T	T												T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		435	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	N	H	C	W	K	E	K	P	E	D	R	P	P	F	S	Q	L	L	S	Q	L	A	E	I	A	E	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T	S
Template Known Secondary structure						T		S	S	G	G	G	S												T
Template Predicted Secondary structure
Template SS confidence
		495	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.