Job Description Q64143 Confidence 100.00% Date Wed Jul 10 14:20:57 BST 2013 Rank 9 Aligned Residues 233 % Identity 74% Template c2y3aB_ PDB info PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941 Resolution 3.30 Å Model Dimensions (Å) X:62.650 Y:136.003 Z:59.902

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		184	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	H	S	Q	Y	Q	E	K	S	K	E	Y	D	R	L	Y	E	E	Y	T	R	T	S	Q	E	I	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	C	H	T	Q	E	Q	H	S	K	D	Y	I	E	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	H	Q	Q	Y	Q	D	K	S	R	E	Y	D	Q	L	Y	E	E	Y	T	R	T	S	Q	E	L	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	G	Q	T	Q	E	K	C	S	K	E	Y	L	G	N
Template Known Secondary structure			S	S							T	T	T																																											T					T
Template Predicted Secondary structure
Template SS confidence
		443	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.
		244	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	R	R	E	G	N	E	K	E	I	E	R	I	M	M	N	Y	D	K	L	K	S	R	L	G	E	I	H	D	S	K	L	R	L	E	Q	D	L	K	K	Q	A	L	D	N	R	E	I	D	K	K	M	N	S	I	K	P	D	L	I
Query Conservation
Alig confidence		.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	E	K	E	M	Q	R	I	L	L	N	S	E	R	L	K	S	R	I	A	E	I	H	E	S	R	T	K	L	E	Q	D	L	R	A	Q	A	S	D	N	R	E	I	D	K	R	M	N	S	L	K	P	D	L	M
Template Known Secondary structure		.	.	.	.	.	.	T	T																																																T
Template Predicted Secondary structure		.	.	.	.	.	.
Template SS confidence
								509	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.
		304	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	L	R	K	I	R	D	Q	H	L	V	W	L	N	H	R	G	V	R	Q	R	R	L	N	A	W	L	G	I	K	N	E	D	S	D	E	S	Y	F	I	N	E	E	D	E	N	L	P	H	Y	D	E	K	T	W	F	V	E	D	I
Query Conservation
Alig confidence																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	L	R	K	I	R	D	Q	Y	L	V	W	L	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	H	H	E	E	R	T	W	Y	V	G	K	I
Template Known Secondary structure								T	T			S				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	G	S	S	T	T	T	B			S
Template Predicted Secondary structure																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		563	.	.	.	.	.	.	570	.	.	.	.	.	.																																		.	.	.	580	.	.	.	.	.	.	.	.	.
		364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	R	V	Q	A	E	D	L	L	Y	G	K	P	D	G	A	F	L	I	R	E	S	S	K	K	G	C	Y	A	C	S	V	V	A	D	G	E	V	K	H	C	V	I	Y	S	T	A	R	G	Y	G	F	A	E	P	Y	N	L	Y	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	R	T	Q	A	E	E	M	L	S	G	K	R	D	G	T	F	L	I	R	E	S	S	Q	R	G	C	Y	A	C	S	V	V	V	D	G	D	T	K	H	C	V	I	Y	R	T	A	T	G	F	G	F	A	E	P	Y	N	L	Y	G
Template Known Secondary structure											T	T	S		T	T	B			B				S	S	T	T									S	S	S										T	T				S	B	T	T	B				S
Template Predicted Secondary structure
Template SS confidence
		622	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.
		424	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	L	K	E	L	V	L	H	Y	Q	Q	T	S	L	V	Q	H	N	D	S	L	N	V	R	L	A	Y	P	V	H	A	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	L	K	E	L	V	L	H	Y	Q	H	A	S	L	V	Q	H	N	D	A	L	T	V	T	L	A	H	P	V	R	A	P
Template Known Secondary structure		S							T	T	S	S	S		S	T	T	T		S	S						S	B		S
Template Predicted Secondary structure
Template SS confidence
		682	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D