Job Description Q64143 Confidence 100.00% Date Wed Jul 10 14:20:57 BST 2013 Rank 3 Aligned Residues 200 % Identity 34% Template c2b3oA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1 Resolution 2.80 Å Model Dimensions (Å) X:44.932 Y:68.420 Z:32.160

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		64	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.		.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		E	W	Y	W	G	D	I	S	R	E	E	V	N	D	K	L	R	D	M	.	P	D	G	T	F	L	V	R	D	A	S	T	K	M	Q	G	D	Y	T	L	T	L	R	K	G	G	N	N	K	L	I	K	I	Y	H	R	D	G	K	Y
Query Conservation																					.
Alig confidence																					.										.
Template Conservation																															.
Template Sequence		R	W	F	H	R	D	L	S	G	L	D	A	E	T	L	L	K	G	R	G	V	H	G	S	F	L	A	R	P	.	S	R	K	N	Q	G	D	F	S	L	S	V	R	V	G	D	Q	V	T	H	I	R	I	Q	N	S	G	D	F	Y
Template Known Secondary structure		T	T	B		S	S																T	T							.		S	S	S	S	S									T	T										S	S	S
Template Predicted Secondary structure																															.
Template SS confidence
		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.		.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.
		123	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	F	S	E	P	L	T	F	T	S	V	V	E	L	I	N	H	Y	H	H	E	S	L	A	Q	Y	N	P	K	L	D	V	K	L	T	Y	P	V	S	R	F	Q	Q	D	Q	L	V	K	E	D	N	I	D	A	V	G	K	N	L	Q
Query Conservation
Alig confidence																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	L	Y	G	G	E	K	F	A	T	L	T	E	L	V	E	Y	Y	T	Q	Q	Q	G	V	L	Q	D	R	D	G	T	I	I	H	L	K	Y	P	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure				T	T	S				S											T	T		S		B			S	S	S			B							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		62	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100
		183	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	F	H	S	Q	Y	Q	E	K	S	K	E	Y	D	R	L	Y	E	E	Y	T	R	T	S	Q	E	I	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	C	H	T	Q	E	Q	H	S	K	D	Y	I	E
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		243	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	F	R	R	E	G	N	E	K	E	I	E	R	I	M	M	N	Y	D	K	L	K	S	R	L	G	E	I	H	D	S	K	L	R	L	E	Q	D	L	K	K	Q	A	L	D	N	R	E	I	D	K	K	M	N	S	I	K	P	D	L
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		303	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	Q	L	R	K	I	R	D	Q	H	L	V	W	L	N	H	R	G	V	R	Q	R	R	L	N	A	W	L	G	I	K	N	E	D	S	D	E	S	Y	F	I	N	E	E	D	E	N	L	P	H	Y	D	E	K	T	W	F	V	E	D
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	C	S	D	P	T	S	E	R	W	Y	H	G	H
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					G	G	G		T	T	B		T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																																																101	.	.	.	.	.	.	.	.	110	.	.	.	.
		363	.	.	.	.	.	.	370	.	.	.	.	.	.		.	.	.	380	.	.	.	.	.		.	.	.	.	390	.	.	.	.	.	.	.						.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Predicted Secondary structure																.										.													.	.	.	.	.
Query SS confidence																.										.													.	.	.	.	.
Query Sequence		I	N	R	V	Q	A	E	D	L	L	Y	G	K	P	.	D	G	A	F	L	I	R	E	S	.	S	K	K	G	C	Y	A	C	S	V	V	A	.	.	.	.	.	D	G	E	V	K	H	C	V	I	Y	S	T	A	R	G	Y	G	F
Query Conservation																.										.													.	.	.	.	.
Alig confidence																.										.													.	.	.	.	.										.
Template Conservation																																																					.
Template Sequence		M	S	G	G	Q	A	E	T	L	L	Q	A	K	G	E	P	W	T	F	L	V	R	E	S	L	S	Q	P	G	D	F	V	L	S	V	L	S	D	Q	P	K	S	P	L	R	V	T	H	I	K	V	.	M	C	E	G	G	R	Y	T
Template Known Secondary structure																	T	T								S	S	S	T	T																							.	B			T	T	S	B	B
Template Predicted Secondary structure																																																					.
Template SS confidence
		115	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.		.	.	.	.	170	.	.	.
		416	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	E	P	Y	N	L	Y	S	S	L	K	E	L	V	L	H	Y	Q	Q	T	S	L	V	Q	H	N	D	S	L	N	V	R	L	A	Y	P	V	H
Query Conservation
Alig confidence																														.
Template Conservation																														.
Template Sequence		V	G	G	L	E	T	F	D	S	L	T	D	L	V	E	H	F	K	K	T	G	I	E	E	A	S	G	A	.	F	V	Y	L	R	Q	P	Y	Y
Template Known Secondary structure		S	S	S	S			B	S	S																S	S	S		.
Template Predicted Secondary structure																														.
Template SS confidence
		178	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.		.	.	.	.	210	.	.	.	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D