Email l.a.kelley@imperial.ac.uk Description P47941 Date Wed Jul 10 14:10:41 BST 2013 Unique Job ID 1079477ba5b26207

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2lqnA_ 100.0 97 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl 2 c2eyzA_ 100.0 61 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii 3 c2dvjA_ 100.0 59 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii 4 c3qwxX_ 100.0 37 PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174 5 c2eyyA_ 100.0 65 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i 6 c3qwyA_ 100.0 37 PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 7 c2l3sA_ 100.0 56 PDB header:structural protein Chain: A: PDB Molecule:autoinhibited crk protein; PDBTitle: structure of the autoinhibited crk 8 c1griA_ 100.0 24 PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2 9 c1ng2A_ 100.0 19 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosolic factor 1; PDBTitle: structure of autoinhibited p47phox 10 c1ov3A_ 100.0 19 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 1; PDBTitle: structure of the p22phox-p47phox complex 11 c2eo3A_ 100.0 99 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of the sh2 domain from human crk-like2 protein 12 d2oq1a1 100.0 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 13 c2gsbA_ 99.9 27 PDB header:signaling protein Chain: A: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1 14 d2eyva1 99.9 80 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 15 c2dlyA_ 99.9 27 PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase 16 c2oq1A_ 99.9 25 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide 17 c2hdxB_ 99.9 26 PDB header:signaling protein Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1 PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide 18 c3gqiB_ 99.9 26 PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:phospholipase c-gamma-1; PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates 19 c3hizB_ 99.9 27 PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha 20 c2shpA_ 99.9 24 PDB header:tyrosine phosphatase Chain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2 21 d1blja_ not modelled 99.9 30 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 22 c2fo0A_ not modelled 99.9 32 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase 23 d2oq1a2 not modelled 99.9 33 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 24 c2crhA_ not modelled 99.9 26 PDB header:signaling protein Chain: A: PDB Molecule:vav proto-oncogene; PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1 25 c2ablA_ not modelled 99.9 33 PDB header:transferase Chain: A: PDB Molecule:abl tyrosine kinase; PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase 26 d3c7ia1 not modelled 99.9 25 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 27 d1fhsa_ not modelled 99.9 21 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 28 d1a81a2 not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 29 d1a81e1 not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 30 d1a81e2 not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 31 d1a81a1 not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 32 c2y3aB_ not modelled 99.9 29 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941 33 c2eo6A_ not modelled 99.9 25 PDB header:signaling protein Chain: A: PDB Molecule:b-cell linker protein; PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk 34 d1csya_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 35 d2izva2 not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 36 c2dlzA_ not modelled 99.9 26 PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the sh2 domain of human protein vav-2 37 d2shpa2 not modelled 99.9 28 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 38 d1rjaa_ not modelled 99.9 33 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 39 d1opka2 not modelled 99.9 33 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 40 c1ka6A_ not modelled 99.9 22 PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py 41 d1jwoa_ not modelled 99.9 32 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 42 d1k9aa2 not modelled 99.9 32 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 43 c2ysxA_ not modelled 99.9 31 PDB header:signaling protein Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase PDBTitle: solution structure of the human ship sh2 domain 44 d1nrva_ not modelled 99.9 25 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 45 c2ozoA_ not modelled 99.9 27 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70 46 c1oplA_ not modelled 99.9 32 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase 47 c2b3oA_ not modelled 99.9 26 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1 48 c2augB_ not modelled 99.9 30 PDB header:signaling protein Chain: B: PDB Molecule:growth factor receptor-bound protein 14; PDBTitle: crystal structure of the grb14 sh2 domain 49 d1pica_ not modelled 99.9 29 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 50 c2eobA_ not modelled 99.9 25 PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2 51 d1r1qa_ not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 52 c1k9aB_ not modelled 99.9 31 PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution 53 d1d4ta_ not modelled 99.9 22 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 54 d1lkka_ not modelled 99.9 33 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 55 d1jyra_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 56 c1x27F_ not modelled 99.9 32 PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas 57 c2vifA_ not modelled 99.9 21 PDB header:signaling protein Chain: A: PDB Molecule:suppressor of cytokine signalling 6; PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide 58 c4fl2A_ not modelled 99.9 25 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch 59 c2ge9A_ not modelled 99.9 26 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase 60 d1o48a_ not modelled 99.9 36 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 61 c3nhnA_ not modelled 99.9 36 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region 62 c1y57A_ not modelled 99.9 30 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor 63 d1g83a2 not modelled 99.9 33 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 64 d1i3za_ not modelled 99.9 31 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 65 c2c9wA_ not modelled 99.9 24 PDB header:transcription regulation Chain: A: PDB Molecule:suppressor of cytokine signaling 2; PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution 66 d1qcfa2 not modelled 99.9 35 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 67 d2cs0a1 not modelled 99.9 28 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 68 c2lctA_ not modelled 99.9 24 PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide 69 c1a81E_ not modelled 99.9 26 PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam 70 d2qmsa1 not modelled 99.9 31 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 71 c2kk6A_ not modelled 99.9 30 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer; PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d 72 c1x6cA_ not modelled 99.9 37 PDB header:signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1 73 c2ci8A_ not modelled 99.9 31 PDB header:translation Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed 74 d1f2fa_ not modelled 99.9 37 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 75 d1bkla_ not modelled 99.9 35 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 76 c2knoA_ not modelled 99.9 27 PDB header:hydrolase Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase; PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1) 77 c2dcrA_ not modelled 99.9 28 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: fully automated solution structure determination of the fes2 sh2 domain 78 d1ayaa_ not modelled 99.9 27 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 79 c3ps5A_ not modelled 99.9 22 PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6; PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1 80 d1fu6a_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 81 c2izvA_ not modelled 99.9 22 PDB header:transcription Chain: A: PDB Molecule:suppressor of cytokine signaling 4; PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution 82 c2c0iA_ not modelled 99.9 31 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 83 d1mila_ not modelled 99.9 30 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 84 d1luia_ not modelled 99.9 29 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 85 d2fcia1 not modelled 99.9 28 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 86 c2h8hA_ not modelled 99.9 30 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor 87 c2hmhA_ not modelled 99.9 25 PDB header:cytokine regulator Chain: A: PDB Molecule:suppressor of cytokine signaling 3; PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide. 88 d1qada_ not modelled 99.9 28 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 89 d2shpa3 not modelled 99.9 34 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 90 c2ekxA_ not modelled 99.9 25 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: solution structure of the human bmx sh2 domain 91 d2c9wa2 not modelled 99.9 27 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 92 c2dm0A_ not modelled 99.9 26 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase txk; PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk 93 c2el8A_ not modelled 99.9 20 PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 2; PDBTitle: solution structure of the human stap2 sh2 domain 94 c1g83A_ not modelled 99.9 35 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: crystal structure of fyn sh3-sh2 95 d1rpya_ not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 96 c1rqqC_ not modelled 99.9 24 PDB header:transferase/signaling protein Chain: C: PDB Molecule:adaptor protein aps; PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps 97 d1xa6a2 not modelled 99.9 17 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 98 c3mazA_ not modelled 99.9 15 PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 1; PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide 99 d1cwea_ not modelled 99.9 36 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 100 c2cr4A_ not modelled 99.8 20 PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain-binding protein 2; PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein 101 c2dbkA_ not modelled 99.8 91 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structures of the sh3 domain of human crk-like2 protein 102 c3gxxB_ not modelled 99.8 17 PDB header:transcription Chain: B: PDB Molecule:transcription elongation factor spt6; PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b 103 d1udla_ not modelled 99.8 33 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 104 c1mv3A_ not modelled 99.8 16 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:myc box dependent interacting protein 1; PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc 105 c2eyxA_ not modelled 99.8 69 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: c-terminal sh3 domain of ct10-regulated kinase 106 c2dx0B_ not modelled 99.8 35 PDB header:hydrolase Chain: B: PDB Molecule:phospholipase c, gamma 2; PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2 107 c2bzxA_ not modelled 99.8 100 PDB header:sh3 domain Chain: A: PDB Molecule:crk-like protein; PDBTitle: atomic model of crkl-sh3c monomer 108 c2ebpA_ not modelled 99.8 27 PDB header:cell adhesion Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1 109 c2dybA_ not modelled 99.8 21 PDB header:oxidoreductase Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: the crystal structure of human p40(phox) 110 c2dx1A_ not modelled 99.8 27 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef 111 c3or8A_ not modelled 99.8 20 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: a tandem sh2 domain in transcription elongation factor spt6 112 c2xp1A_ not modelled 99.8 14 PDB header:transcription Chain: A: PDB Molecule:spt6; PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6 113 c3jv3A_ not modelled 99.7 32 PDB header:protein binding Chain: A: PDB Molecule:intersectin-1; PDBTitle: structure of sh3e-dh unit of murine intersectin-1l 114 c3nmzD_ not modelled 99.7 20 PDB header:cell adhesion/cell cycle Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crytal structure of apc complexed with asef 115 c2cubA_ not modelled 99.7 24 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1 116 c2jxbA_ not modelled 99.7 24 PDB header:signaling protein complex Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain, PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex 117 c2ysqA_ not modelled 99.7 26 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9; PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9 118 c2nwmA_ not modelled 99.7 30 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin 119 d1ng2a2 not modelled 99.7 17 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 120 c2ed0A_ not modelled 99.7 22 PDB header:signaling protein Chain: A: PDB Molecule:abl interactor 2; PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)