Job Description P24604 Confidence 100.00% Date Tue Jul 30 13:00:36 BST 2013 Rank 118 Aligned Residues 262 % Identity 37% Template c3zosA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epithelial discoidin domain-containing receptor 1; PDBTitle: structure of the ddr1 kinase domain in complex with ponatinib Resolution 1.92 Å

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		361	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390																		.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	W	E	I	N	P	S	E	L	T	F	M	R	E	L	G	S	G	L	F	G	V	V	R	L	G	K	W	R	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	Y	K	V	A	I	K	A	I	R	E	G	A
Query Conservation																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		R	V	D	F	P	R	S	R	L	R	F	K	E	K	L	G	E	G	Q	F	G	E	V	H	L	C	E	V	D	S	P	Q	D	L	V	S	L	D	F	P	L	N	V	R	K	G	H	P	L	L	V	A	V	K	I	L	R	P	D	A
Template Known Secondary structure							G	G	G											T	T									S	S	G	G	G	G		S	S	S	S						T	T	S											T	T
Template Predicted Secondary structure
Template SS confidence
		602	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.
		404	.	.			.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.
Predicted Secondary structure					.	.																																																			.	.	.	.	.
Query SS confidence					.	.																																																			.	.	.	.	.
Query Sequence		M	C	E	.	.	E	D	F	I	E	E	A	K	V	M	M	K	L	T	H	P	K	L	V	Q	L	Y	G	V	C	T	Q	Q	K	P	I	Y	I	V	T	E	F	M	E	R	G	C	L	L	N	F	L	R	Q	R	.	.	.	.	.
Query Conservation					.	.																																																			.	.	.	.	.
Alig confidence					.	.																																																			.	.	.	.	.
Template Conservation
Template Sequence		T	K	N	A	R	N	D	F	L	K	E	V	K	I	M	S	R	L	K	D	P	N	I	I	R	L	L	G	V	C	V	Q	D	D	P	L	C	M	I	T	D	Y	M	E	N	G	D	L	N	Q	F	L	S	A	H	Q	L	E	D	A
Template Known Secondary structure																						T	T	B									S	S	S	S									T	T		B							T
Template Predicted Secondary structure
Template SS confidence
		662	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.
				457	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.
Predicted Secondary structure		.	.
Query SS confidence		.	.
Query Sequence		.	.	Q	G	H	F	S	R	D	M	L	L	S	M	C	Q	D	V	C	E	G	M	E	Y	L	E	R	N	S	F	I	H	R	D	L	A	A	R	N	C	L	V	N	E	A	G	V	V	K	V	S	D	F	G	M	A	R	Y	V	L
Query Conservation		.	.
Alig confidence		.	.
Template Conservation
Template Sequence		A	Q	G	P	T	I	S	Y	P	M	L	L	H	V	A	A	Q	I	A	S	G	M	R	Y	L	A	T	L	N	F	V	H	R	D	L	A	T	R	N	C	L	V	G	E	N	F	T	I	K	I	A	D	F	G	M	S	R	N	L	Y
Template Known Secondary structure				S																									T	T				S			S	G	G	G					G	G	G								T	T	S
Template Predicted Secondary structure
Template SS confidence
		733	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.
		515	.	.		.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.		560	.	.	.	.	.	.	.	.	.	570	.	.
Predicted Secondary structure					.																																											.
Query SS confidence					.																																											.
Query Sequence		D	D	Q	.	Y	T	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E	V	F	N	Y	S	R	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	I	F	T	.	E	G	R	M	P	F	E	K	N	T	N	Y	E
Query Conservation					.																																											.
Alig confidence					.																																											.
Template Conservation
Template Sequence		A	G	D	Y	Y	R	V	Q	G	R	A	V	L	P	I	R	W	M	A	W	E	C	I	L	M	G	K	F	T	T	A	S	D	V	W	A	F	G	V	T	L	W	E	V	L	M	L	C	R	A	Q	P	F	G	Q	L	T	D	E	Q
Template Known Secondary structure		G	G	G						T	T					G	G	G	S																												T	T	T		S		T	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		793	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.
		573	.	.	.	.	.	.	580								.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.
Predicted Secondary structure										.	.	.	.	.	.	.
Query SS confidence										.	.	.	.	.	.	.
Query Sequence		V	V	T	M	V	T	R	G	.	.	.	.	.	.	.	H	R	L	H	R	P	K	L	A	T	K	Y	L	Y	E	V	M	L	R	C	W	Q	E	R	P	E	G	R	P	S	L	E	D	L	L	R	T	I	D	E	L	V
Query Conservation										.	.	.	.	.	.	.
Alig confidence										.	.	.	.	.	.	.
Template Conservation
Template Sequence		V	I	E	N	A	G	E	F	F	R	D	Q	G	R	Q	V	Y	L	S	R	P	P	A	C	P	Q	G	L	Y	E	L	M	L	R	C	W	S	R	E	S	E	Q	R	P	P	F	S	Q	L	H	R	F	L	A	E	D	A
Template Known Secondary structure												T	S	S									T	T													T		S	S	G	G	G	S												T
Template Predicted Secondary structure
Template SS confidence
		853	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D