Job Description P24604 Confidence 100.00% Date Tue Jul 30 13:00:36 BST 2013 Rank 212 Aligned Residues 252 % Identity 26% Template c3zonA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: human tyk2 pseudokinase domain bound to a kinase inhibitor Resolution 2.15 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.		.	.	.	410	.	.	.	.	.	.	.	.	.	420
Predicted Secondary structure																																															.
Query SS confidence																																															.
Query Sequence		W	E	I	N	P	S	E	L	T	F	M	R	E	L	G	S	G	L	F	G	V	V	R	L	G	K	W	R	A	Q	Y	K	V	A	I	K	A	I	R	E	G	A	M	C	E	.	E	D	F	I	E	E	A	K	V	M	M	K	L	T
Query Conservation																																															.
Alig confidence																																															.
Template Conservation
Template Sequence		H	R	V	D	Q	K	E	I	T	Q	L	S	H	L	G	Q	G	T	R	T	N	V	Y	E	G	R	L	R	V	E	L	R	V	V	L	K	V	L	D	P	S	H	H	D	I	A	L	A	F	Y	E	T	A	S	L	M	S	Q	V	S
Template Known Secondary structure						G	G	G											T	T																					S																	T	T
Template Predicted Secondary structure
Template SS confidence
		582	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.
		421	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Predicted Secondary structure
Query SS confidence
Query Sequence		H	P	K	L	V	Q	L	Y	G	V	C	T	Q	Q	K	P	I	Y	I	V	T	E	F	M	E	R	G	C	L	L	N	F	L	R	Q	R	Q	G	H	F	S	R	D	M	L	L	S	M	C	Q	D	V	C	E	G	M	E	Y	L	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	T	H	L	A	F	V	H	G	V	C	V	R	G	P	E	N	I	M	V	T	E	Y	V	E	H	G	P	L	D	V	W	L	R	R	E	R	G	H	V	P	M	A	W	K	M	V	V	A	Q	Q	L	A	S	A	L	S	Y	L	E
Template Known Secondary structure			T	T	B										T	T										T	T		B								T	T	T
Template Predicted Secondary structure
Template SS confidence
		667	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.
		481	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510			.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.
Predicted Secondary structure																																.	.
Query SS confidence																																.	.
Query Sequence		R	N	S	F	I	H	R	D	L	A	A	R	N	C	L	V	N	E	A	G	V	V	K	V	S	D	F	G	M	A	.	.	R	Y	V	L	D	D	Q	Y	T	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E	V	F	N	Y
Query Conservation																																.	.
Alig confidence																																.	.																											.	.
Template Conservation																																																												.	.
Template Sequence		N	K	N	L	V	H	G	N	V	C	G	R	N	I	L	L	A	R	L	G	L	A	E	G	T	S	P	F	I	K	L	S	D	P	G	V	G	L	G	A	L	S	R	E	E	R	V	E	R	I	P	W	L	A	P	E	C	L	.	.
Template Known Secondary structure			T	T							S	G	G	G									S	T	T												S		G	G	G	S								T	T	T	T	S		G	G	G		.	.
Template Predicted Secondary structure																																																												.	.
Template SS confidence
		727	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.
		539	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	R	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	I	F	T	E	G	R	M	P	F	E	K	N	T	N	Y	E	V	V	T	M	V	T	R	G	H	R	L	H	R	P	K	L	A	T	K	Y	L	Y	E	V	M	L
Query Conservation
Alig confidence		.																																																	.	.	.	.	.
Template Conservation		.																																																	.	.	.	.	.
Template Sequence		.	P	L	S	T	A	M	D	K	W	G	F	G	A	T	L	L	E	I	C	F	D	G	E	A	P	L	Q	S	R	S	P	S	E	K	E	H	F	Y	Q	R	Q	H	R	L	P	E	P	Q	.	.	.	.	.	L	A	T	L	T	S
Template Known Secondary structure		.				T	T															T	T	T			T	T	T	T	S											T	T								.	.	.	.	.
Template Predicted Secondary structure		.																																																	.	.	.	.	.
Template SS confidence
			785	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.						.	.	.	.	.	.
		599	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	C	W	Q	E	R	P	E	G	R	P	S	L	E	D	L	L	R	T	I	D	E	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	C	L	T	Y	E	P	T	Q	R	P	S	F	R	T	I	L	R	D	L	T	R	L
Template Known Secondary structure				T		S	S	G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		847	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D