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Job DescriptionP24604
Confidence100.00%DateTue Jul 30 13:00:36 BST 2013
Rank119Aligned Residues333
% Identity21%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å
Model Dimensions (Å)X:55.128 Y:63.172 Z:44.813

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.
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Query Sequence  NFNTILEEILIKRSQQKKKTSLLNYKERLCVLPKSVLSYYEGRAEKKYRKGVIDISKIKC
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Template Sequence  DVAIVKEGWLHKRGE. . . . . YIKTWRPRYFLLKNDGTFIG. YKERPQDVEAPLNNFSVAQ
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S.....SS

TTSB.SS

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GGGB
TT
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   3......10....... ..20.........30....... ..40.........50......
 
   62.......70.........80.........90.. .......100.........110.........120
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Query Sequence  VEIVKNDDGVIPCQNKFPFQVVHDANTLYIF. APSPQSRDRWVKKLKEEIKNNNNIMIKY
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Template Sequence  CQLMKTE. . . . . RPRPNTFIIRCLQWTTVIERTFTPEEREEWTTAIQTVADGLKKQVTM.
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B

.....SSSSS
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TTGGGTT


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   60...... ...70.........80.........90.........100.........110...
 
   121........130.........140.........150.........160.........170.........180
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Query Sequence  HPKFWADGSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAPEIKKRRPPPPIPPEEENTE
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   181........190.........200.........210.........220.........230.........240
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Query Sequence  EIVVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGSEGYIPSNYVTGKKSNN
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   241........250.........260.........270.........280.........290.........300
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Query Sequence  LDQYEWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYH
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   301........310.........320.........330.........340.........350.........360
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Query Sequence  IKETATSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYD
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   361........370.........380.........390 .........400.........410.........
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Query Sequence  KWEINPSELTFMRELGSGLFGVVRLGKWRA. QYKVAIKAIREGAMCEEDFIEEAKVMMKL
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Template Sequence  . . . . . . NEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNS
Template Known Secondary structure  ......TSTTTTT

......GGGS



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   148.150.........160.........170.........180.. .......190.....
 
   420.........430.........440.........450.........460.........470.........
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Query Sequence  THPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLSMCQDVCEGMEYL
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Template Sequence  RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER. VFSEDRARFYGAEIVSALDYL
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TTB


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   206...210.........220.........230.........240... ......250.........260....
 
   480.. .......490.........500.........510.........520.........530........
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Query Sequence  ERN. SFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNY
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Template Sequence  HSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEP. . . . . . . . . . . . . . . EYLAPEVLED
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GGG
TTS




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   265....270.........280.........290......... 300.........
 
   539540.........550.........560.........570.........580.........590........
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Query Sequence  SRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLHRPKLATKYLYEVML
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Template Sequence  NDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLS
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   324.....330.........340.... .....350.........360..... ....370.........380.
 
   599600........ .610......
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Query Sequence  RCWQERPEGR. . . . . PSLEDLLR
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Template Conservation    
  

  
     

  
 
 
Template Sequence  GLLKKDPKQRLGGGSEDAKEIMQ
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SSTTTSTT
STTTT
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   382.......390.........400....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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