Job Description P24604 Confidence 100.00% Date Tue Jul 30 13:00:36 BST 2013 Rank 201 Aligned Residues 242 % Identity 21% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		368	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.		390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.
Predicted Secondary structure																								.																																	.	.	.	.	.
Query SS confidence																								.																																	.	.	.	.	.
Query Sequence		E	L	T	F	M	R	E	L	G	S	G	L	F	G	V	V	R	L	G	K	W	R	.	A	Q	Y	K	V	A	I	K	A	I	R	E	G	A	M	C	E	E	D	F	I	E	E	A	K	V	M	M	K	L	T	H	.	.	.	.	.
Query Conservation																								.																																	.	.	.	.	.
Alig confidence																								.																																	.	.	.	.	.
Template Conservation
Template Sequence		R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	H	K	V	H	Q	H	V	A	L	K	M	V	R	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K	Q	D	K	D	N
Template Known Secondary structure		T										S	S	S									T	T	T	T										S																				T	T		T	T	S
Template Predicted Secondary structure
Template SS confidence
		148	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
			422	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.		460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.																																							.
Query SS confidence		.																																							.
Query Sequence		.	P	K	L	V	Q	L	Y	G	V	C	T	Q	Q	K	P	I	Y	I	V	T	E	F	M	E	R	G	C	L	L	N	F	L	R	Q	R	Q	G	H	.	F	S	R	D	M	L	L	S	M	C	Q	D	V	C	E	G	M	E	Y	L
Query Conservation		.																																							.
Alig confidence		.																								.															.
Template Conservation																										.
Template Sequence		T	M	N	V	I	H	M	L	E	N	F	T	F	R	N	H	I	C	M	T	F	E	L	L	.	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C	L	D	A	L
Template Known Secondary structure			S		B										T	T										.			B								T	T	T
Template Predicted Secondary structure																										.
Template SS confidence
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.		.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
		480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500			.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.
Predicted Secondary structure																							.	.
Query SS confidence																							.	.
Query Sequence		E	R	N	S	F	I	H	R	D	L	A	A	R	N	C	L	V	N	E	A	G	.	.	V	V	K	V	S	D	F	G	M	A	R	Y	V	L	D	D	Q	Y	T	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E	V	F	N
Query Conservation																							.	.
Alig confidence																							.	.																							.	.	.	.	.
Template Conservation																																															.	.	.	.	.
Template Sequence		H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S	S	C	Y	E	H	Q	R	V	Y	T	I	Q	S	.	.	.	.	.	R	F	Y	R	A	P	E	V	I	L
Template Known Secondary structure					T				S			S	G	G	G				S	S	T	T	S									T	T				T	T									.	.	.	.	.	G	G	G
Template Predicted Secondary structure																																															.	.	.	.	.
Template SS confidence
		267	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.						.	.	.	.	.	.	.	.	320	.
		538	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.
Predicted Secondary structure																																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		Y	S	R	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	I	F	T	E	G	R	M	P	F	E	K	N	T	N	Y	E	V	V	T	M	V	T	R	G	H	R	L	H	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																								.																									.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																								.
Template Sequence		G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K	L	L	D	A	S	K	R	A	K	N
Template Known Secondary structure		T	B				T																	.	S	S		S	S			S	S																						T	B	T	T
Template Predicted Secondary structure																								.
Template SS confidence
		323	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.		.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
																																												585	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	P	K	L	A	T	K	Y	L	Y	E	V	M	L	R	C	W	Q
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	L	K	Q	C	L	E
Template Known Secondary structure			B					B	T	T	S																T	T						S	T	T		S						T	T	T														T
Template Predicted Secondary structure
Template SS confidence
		382	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.
		603	.	.	.	.	.	.	610	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	R	P	E	G	R	P	S	L	E	D	L	L	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		W	D	P	A	V	R	M	T	P	G	Q	A	L	R
Template Known Secondary structure		S	S	T	T	T	S								T
Template Predicted Secondary structure
Template SS confidence
		445	.	.	.	.	450	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D