|   |   |
362 | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | |
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | |
|
. | . | . | 410 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
| . |
|
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|
|
|
|
|
| . |
. |
|
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|
|
|
|
| Query Sequence |   |
W | E | I | N | P | S | E | L | T | F | M | R | E | L | G | S | G | L | F | G | V | V | R | L | G | K | W | R | . |
A | Q | Y | K | V | A | I | K | A | I | R | E | G | A | M | C | E | . |
. |
E | D | F | I | E | E | A | K | V | M | M | K |
| Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   | . |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   | . | . |   |   |
|   |   |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
| . |
|
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|
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|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| Template Sequence |   |
W | S | I | N | R | D | D | Y | E | L | Q | E | V | I | G | S | G | A | T | A | V | V | Q | A | A | Y | C | A | P | K | K | E | K | V | A | I | K | R | I | N | L | E | K | C | Q | T | S | M | D | E | L | L | K | E | I | Q | A | M | S | Q |
| Template Known Secondary structure |   |
|
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  | T | T | T | T | T |
|
| T | T | T | T |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
|   |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
419 | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
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|
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|
|
|
|
| Query Sequence |   |
L | T | H | P | K | L | V | Q | L | Y | G | V | C | T | Q | Q | K | P | I | Y | I | V | T | E | F | M | E | R | G | C | L | L | N | F | L | R | . |
. |
. |
. |
. |
. |
. |
Q | R | Q | G | H | F | S | R | D | M | L | L | S | M | C | Q | D |
| Query Conservation |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
C | H | H | P | N | I | V | S | Y | Y | T | S | F | V | V | K | D | E | L | W | L | V | M | K | L | L | S | G | G | S | V | L | D | I | I | K | H | I | V | A | K | G | E | H | K | S | G | V | L | D | E | S | T | I | A | T | I | L | R | E |
| Template Known Secondary structure |   |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
| S | S |
|  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
472 | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | C | E | G | M | E | Y | L | E | R | N | S | F | I | H | R | D | L | A | A | R | N | C | L | V | N | E | A | G | V | V | K | V | S | D | F | G | M | A | R | Y | V | L | D | D | Q | Y | T | S | S | S | G | A | K | F | P | V | K | W | C |
| Query Conservation |   |
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |
|   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |
|
|   |   |
|   |
| Template Sequence |   |
V | L | E | G | L | E | Y | L | H | K | N | G | Q | I | H | R | D | V | K | A | G | N | I | L | L | G | E | D | G | S | V | Q | I | A | D | F | G | V | S | A | F | L | A | T | G | G | D | I | T | R | . |
N | K | V | G | T | P | C | W | M |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
| S | G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
| T | T |  |  |  |  |  |  | T | T | S | S |
| B | T | . | T |
|
|
|
| G | G | G |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | |
180 | . | . | . | . | . | . | . | . |
|   |
|   |   |
532 | . | . | . | . | . | . | . | |
540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | |
. | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| Query Sequence |   |
P | P | E | V | F | N | Y | S | . |
R | F | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | I | F | T | E | G | R | M | P | F | E | K | N | T | N | Y | E | V | V | T | M | V | T | R | G | H | R | . |
L | H | R | P | K | L | A |
| Query Conservation |   |
|
|
|   |
|   |   |   | . |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |
|   |   |
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
A | P | E | V | M | E | Q | V | R | G | Y | D | F | K | A | D | I | W | S | F | G | I | T | A | I | E | L | A | T | . |
G | A | A | P | Y | H | K | Y | P | P | M | K | V | L | M | L | T | L | Q | N | D | P | P | S | L | E | T | K | K | Y |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S |
|
|
|
| T | T |
|
|
|
|
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
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|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
194 | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | |
. | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
|   |
|   |   |
590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | K | Y | L | Y | E | V | M | L | R | C | W | Q | E | R | P | E | G | R | P | S | L | E | D | L | L | R |
| Query Conservation |   |
  |   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |
|
|
|   |
| Template Sequence |   |
G | K | S | F | R | K | M | I | S | L | C | L | Q | K | D | P | E | K | R | P | T | A | A | E | L | L | R |
| Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |
|
| S | S | T | T | T | S |
|
|  |  |  |  | T | S |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
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