Job Description P24604 Confidence 100.00% Date Tue Jul 30 13:00:36 BST 2013 Rank 137 Aligned Residues 238 % Identity 24% Template c2r7bA_ PDB info PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor Resolution 2.70 Å

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		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.		390	.	.	.	.	.	.	.	.	.	400					.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Predicted Secondary structure																										.												.	.	.	.
Query SS confidence																										.												.	.	.	.
Query Sequence		P	S	E	L	T	F	M	R	E	L	G	S	G	L	F	G	V	V	R	L	G	K	W	R	.	A	Q	Y	K	V	A	I	K	A	I	R	.	.	.	.	E	G	A	M	C	E	E	D	F	I	E	E	A	K	V	M	M	K	L	T
Query Conservation																										.												.	.	.	.
Alig confidence																										.												.	.	.	.
Template Conservation
Template Sequence		P	E	D	F	K	F	G	K	I	L	G	E	G	S	F	S	T	V	V	L	A	R	E	L	A	T	S	R	E	Y	A	I	K	I	L	E	K	R	H	I	I	K	E	N	K	V	P	Y	V	T	R	E	R	D	V	M	S	R	L	D
Template Known Secondary structure		G	G	G											S	S									T	T	T																	T	T														T
Template Predicted Secondary structure
Template SS confidence
		79	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.
		421	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Predicted Secondary structure
Query SS confidence
Query Sequence		H	P	K	L	V	Q	L	Y	G	V	C	T	Q	Q	K	P	I	Y	I	V	T	E	F	M	E	R	G	C	L	L	N	F	L	R	Q	R	Q	G	H	F	S	R	D	M	L	L	S	M	C	Q	D	V	C	E	G	M	E	Y	L	E
Query Conservation
Alig confidence																																							.
Template Conservation																																							.
Template Sequence		H	P	F	F	V	K	L	Y	F	T	F	Q	D	D	E	K	L	Y	F	G	L	S	Y	A	K	N	G	E	L	L	K	Y	I	R	K	I	G	.	S	F	D	E	T	C	T	R	F	Y	T	A	E	I	V	S	A	L	E	Y	L	H
Template Known Secondary structure			T	T	B										S	S										T	T		B								S	S	.	S
Template Predicted Secondary structure																																							.
Template SS confidence
		139	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.		.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.
		481	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Predicted Secondary structure
Query SS confidence
Query Sequence		R	N	S	F	I	H	R	D	L	A	A	R	N	C	L	V	N	E	A	G	V	V	K	V	S	D	F	G	M	A	R	Y	V	L	D	D	Q	Y	T	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E	V	F	N	Y	S	R
Query Conservation
Alig confidence																																.	.	.	.	.	.	.	.	.	.
Template Conservation																																.	.	.	.	.	.	.	.	.	.
Template Sequence		G	K	G	I	I	H	R	D	L	K	P	E	N	I	L	L	N	E	D	M	H	I	Q	I	T	D	F	G	T	A	.	.	.	.	.	.	.	.	.	.	K	V	L	F	V	G	T	A	Q	Y	V	S	P	E	L	L	T	E	K	S
Template Known Secondary structure			T	T								T	T	T					T	T	S								T	T		.	.	.	.	.	.	.	.	.	.								G	G	G								S	S
Template Predicted Secondary structure																																.	.	.	.	.	.	.	.	.	.
Template SS confidence
		198	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.											.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.
		541	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Predicted Secondary structure
Query SS confidence
Query Sequence		F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	I	F	T	E	G	R	M	P	F	E	K	N	T	N	Y	E	V	V	T	M	V	T	R	G	H	R	L	H	R	P	K	L	A	T	K	Y	L	Y	E	V	M	L	R	C
Query Conservation
Alig confidence																					.																						.
Template Conservation																					.																						.
Template Sequence		A	C	K	S	S	D	L	W	A	L	G	C	I	I	Y	Q	L	V	A	.	G	L	P	P	F	R	A	G	N	E	Y	L	I	F	Q	K	I	I	K	L	E	.	Y	D	F	P	E	K	F	F	P	K	A	R	D	L	V	E	K	L
Template Known Secondary structure																					.	S	S		S				S	S											T		.					S	S	S										T	T
Template Predicted Secondary structure																					.																						.
Template SS confidence
		259	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.		.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.		.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
		601	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	Q	E	R	P	E	G	R	P	S	L	E	D	L	L	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	V	L	D	A	T	K	R	L	G	C	E	E	M	E	G
Template Known Secondary structure		S		S	S	T	T	S	S	T	T	S	G	G	G	T	T
Template Predicted Secondary structure
Template SS confidence
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D