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Job DescriptionP24604
Confidence100.00%DateTue Jul 30 13:00:36 BST 2013
Rank18Aligned Residues264
% Identity36%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å
Model Dimensions (Å)X:49.618 Y:57.755 Z:41.529

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   360.........370.........380......... 390.........400...... ...410.
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Query Sequence  DKWEINPSELTFMRELGSGLFGVVRLGKWR. . . . . . AQYKVAIKAIREGAMCE. . EDFIE
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Template Sequence  PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLS
Template Known Secondary structure  TTTB

GGG
SSSTGGG
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TT

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   715....720.........730.........740.........750.........760.........770....
 
   412.......420.........430.........440.........450....... ..460....
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Query Sequence  EAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQ. . . . . . . GHFSRDM
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Template Sequence  EFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGD
Template Known Secondary structure  TT


TTB


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TT
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   775....780.........790.........800.........810.........820.........830....
 
   465....470.........480.........490.........500.........510.. .......520...
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Query Sequence  LLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARY. VLDDQYTSSSG
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Template Sequence  LISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQ
Template Known Secondary structure  TT



SGGGTTT


TT

TTTS

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   851........860.........870.........880.........890.........900.........910
 
   524.....530.........540.........550.........560.........570.........580...
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Query Sequence  AKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRL
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Template Sequence  GRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRM
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   911........920.........930.........940.........950.........960.........970
 
   584.....590.........600.........610.........620...
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Query Sequence  HRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDELVE
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Template Sequence  ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMV
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TT

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   971........980.........990.........1000.........1010
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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