Job Description P24604 Confidence 100.00% Date Tue Jul 30 13:00:36 BST 2013 Rank 3 Aligned Residues 433 % Identity 40% Template c1y57A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor Resolution 1.91 Å Model Dimensions (Å) X:62.343 Y:96.126 Z:45.890

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		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220		.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Predicted Secondary structure																																											.
Query SS confidence																																											.
Query Sequence		E	E	I	V	V	A	M	Y	D	F	Q	A	T	E	A	H	D	L	R	L	E	R	G	Q	E	Y	I	I	L	E	K	N	D	L	H	W	W	R	A	R	D	.	K	Y	G	S	E	G	Y	I	P	S	N	Y	V	T	G	K	K	S
Query Conservation																																											.
Alig confidence																																											.															.	.
Template Conservation																																																										.	.
Template Sequence		V	T	T	F	V	A	L	Y	D	Y	E	S	R	T	E	T	D	L	S	F	K	K	G	E	R	L	Q	I	V	N	N	T	E	G	D	W	W	L	A	H	S	L	S	T	G	Q	T	G	Y	I	P	S	N	Y	V	A	.	.	P	S
Template Known Secondary structure		T	T					S	S		B				S	S	S	B			B		T	T						S			S	S	S	S							T	T	T								G	G	G			.	.		T
Template Predicted Secondary structure																																																										.	.
Template SS confidence
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.			.	140
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.		.	.	.	.	.	270	.	.	.	.		.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure																												.											.
Query SS confidence																												.											.
Query Sequence		N	N	L	D	Q	Y	E	W	Y	C	R	N	T	N	R	S	K	A	E	Q	L	L	R	T	E	D	.	K	E	G	G	F	M	V	R	D	S	.	S	Q	P	G	L	Y	T	V	S	L	Y	T	K	F	G	G	E	G	S	S	G	F
Query Conservation																												.											.
Alig confidence																												.											.																		.
Template Conservation																																																									.
Template Sequence		D	S	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	N	A	K	.	G	L	N	V
Template Known Secondary structure		T	S	G	G	G	S	T	T				S											T		T	T			T	T								S	S	S	T	T											T	T	T	.
Template Predicted Secondary structure																																																									.
Template SS confidence
		141	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.		.	.	.	.
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	H	Y	H	I	K	E	T	A	T	S	P	K	K	Y	Y	L	A	E	K	H	A	F	G	S	I	P	E	I	I	E	Y	H	K	H	N	A	A	G	L	V	T	R	L	R	Y	P	V	S	T	K	G	K	N	A	P	T	T	A	G
Query Conservation
Alig confidence														.	.																																					.	.	.
Template Conservation														.	.																																					.	.	.
Template Sequence		K	H	Y	K	I	R	K	L	D	S	G	G	.	.	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	T	.	.	.	S	K	P	Q	T	Q	G
Template Known Secondary structure										S	S	S		.	.			S	S	T	T	S			S	S													T	T	S	S	S					B				.	.	.						S	S
Template Predicted Secondary structure														.	.																																					.	.	.
Template SS confidence
		200	.	.	.	.	.	.	.	.	.	210	.			.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.				.	.	250	.	.	.	.
		357	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	S	Y	D	K	W	E	I	N	P	S	E	L	T	F	M	R	E	L	G	S	G	L	F	G	V	V	R	L	G	K	W	R	A	Q	Y	K	V	A	I	K	A	I	R	E	G	A	M	C	E	E	D	F	I	E	E	A	K	V	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q	V	M
Template Known Secondary structure						T	T	B			G	G	G											T	T									T	T	T										T	T	S	S
Template Predicted Secondary structure
Template SS confidence
		255	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.
		417	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.		460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
Predicted Secondary structure																																													.
Query SS confidence																																													.
Query Sequence		M	K	L	T	H	P	K	L	V	Q	L	Y	G	V	C	T	Q	Q	K	P	I	Y	I	V	T	E	F	M	E	R	G	C	L	L	N	F	L	R	Q	R	Q	G	H	.	F	S	R	D	M	L	L	S	M	C	Q	D	V	C	E	G
Query Conservation																																													.
Alig confidence																		.																											.
Template Conservation																		.
Template Sequence		K	K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G
Template Known Secondary structure							T	T	B									.	S	S	S									T	T									S
Template Predicted Secondary structure																		.
Template SS confidence
		315	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
		476	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	E	Y	L	E	R	N	S	F	I	H	R	D	L	A	A	R	N	C	L	V	N	E	A	G	V	V	K	V	S	D	F	G	M	A	R	Y	V	L	D	D	Q	Y	T	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A
Template Known Secondary structure								T	T				S			S	G	G	G					G	G	G								T	T						S	S						T	T	T	T		S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		374	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.
		536	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	N	Y	S	R	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	I	F	T	E	G	R	M	P	F	E	K	N	T	N	Y	E	V	V	T	M	V	T	R	G	H	R	L	H	R	P	K	L	A	T	K	Y	L	Y	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D
Template Known Secondary structure																									T	T	S			S	S	T	T												T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		434	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	M	L	R	C	W	Q	E	R	P	E	G	R	P	S	L	E	D	L	L	R	T	I	D	E	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y
Template Known Secondary structure							T		S	S	G	G	G	S												T
Template Predicted Secondary structure
Template SS confidence
		494	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.