Phyre 2 Results for P24604

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | P24604
Date | Tue Jul 30 13:00:36 BST 2013
Unique Job ID | 0c49007f439466a0
Sequence | MNFNTILEEI ... Download FASTA

Summary |

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å): | X:65.399 Y:72.172 Z:59.391
| Close Jmol

Model (left) based on template c2fo0A_
Top template information
PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
Confidence and coverage
Confidence: | 100.0% | Coverage: | 72%
453 residues ( 72% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
570 residues ( 90%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol
For other options to view your downloaded structure offline see the FAQ

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | N | F | N | T | I | L | E | E | I | L | I | K | R | S | Q | Q | K | K | K | T | S | L | L | N | Y | K | E | R | L | C | V | L | P | K | S | V | L | S | Y | Y | E | G | R | A | E | K | K | Y | R | K | G | V | I | D | I | S | K | I | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | C | V | E | I | V | K | N | D | D | G | V | I | P | C | Q | N | K | F | P | F | Q | V | V | H | D | A | N | T | L | Y | I | F | A | P | S | P | Q | S | R | D | R | W | V | K | K | L | K | E | E | I | K | N | N | N | N | I | M | I | K | Y
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | H | P | K | F | W | A | D | G | S | Y | Q | C | C | R | Q | T | E | K | L | A | P | G | C | E | K | Y | N | L | F | E | S | S | I | R | K | T | L | P | P | A | P | E | I | K | K | R | R | P | P | P | P | I | P | P | E | E | E | N | T | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | E | I | V | V | A | M | Y | D | F | Q | A | T | E | A | H | D | L | R | L | E | R | G | Q | E | Y | I | I | L | E | K | N | D | L | H | W | W | R | A | R | D | K | Y | G | S | E | G | Y | I | P | S | N | Y | V | T | G | K | K | S | N | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | L | D | Q | Y | E | W | Y | C | R | N | T | N | R | S | K | A | E | Q | L | L | R | T | E | D | K | E | G | G | F | M | V | R | D | S | S | Q | P | G | L | Y | T | V | S | L | Y | T | K | F | G | G | E | G | S | S | G | F | R | H | Y | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | I | K | E | T | A | T | S | P | K | K | Y | Y | L | A | E | K | H | A | F | G | S | I | P | E | I | I | E | Y | H | K | H | N | A | A | G | L | V | T | R | L | R | Y | P | V | S | T | K | G | K | N | A | P | T | T | A | G | F | S | Y | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | K | W | E | I | N | P | S | E | L | T | F | M | R | E | L | G | S | G | L | F | G | V | V | R | L | G | K | W | R | A | Q | Y | K | V | A | I | K | A | I | R | E | G | A | M | C | E | E | D | F | I | E | E | A | K | V | M | M | K | L | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | H | P | K | L | V | Q | L | Y | G | V | C | T | Q | Q | K | P | I | Y | I | V | T | E | F | M | E | R | G | C | L | L | N | F | L | R | Q | R | Q | G | H | F | S | R | D | M | L | L | S | M | C | Q | D | V | C | E | G | M | E | Y | L | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | R | N | S | F | I | H | R | D | L | A | A | R | N | C | L | V | N | E | A | G | V | V | K | V | S | D | F | G | M | A | R | Y | V | L | D | D | Q | Y | T | S | S | S | G | A | K | F | P | V | K | W | C | P | P | E | V | F | N | Y | S | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | F | S | S | K | S | D | V | W | S | F | G | V | L | M | W | E | I | F | T | E | G | R | M | P | F | E | K | N | T | N | Y | E | V | V | T | M | V | T | R | G | H | R | L | H | R | P | K | L | A | T | K | Y | L | Y | E | V | M | L | R | C
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630
Sequence |  | W | Q | E | R | P | E | G | R | P | S | L | E | D | L | L | R | T | I | D | E | L | V | E | C | E | E | T | F | G | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)
? | Disordered ( 21%)
| Alpha helix ( 24%)
| Beta strand ( 25%)

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c2fo0A_ |

### PDB 2fo0 chain A

Region: 166 - 629
Aligned: 453
Modelled: 458
Confidence: 100.0%
Identity: 39%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2
2 |
| c1oplA_ |

### PDB 1opl chain A

Region: 179 - 630
Aligned: 441
Modelled: 446
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2
3 |
| c1y57A_ |

### PDB 1y57 chain A

Region: 180 - 621
Aligned: 433
Modelled: 442
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2
4 |
| c2h8hA_ |

### PDB 2h8h chain A

Region: 182 - 620
Aligned: 430
Modelled: 439
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2
5 |
| c1k9aB_ |

### PDB 1k9a chain B

Region: 176 - 625
Aligned: 427
Modelled: 449
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2
6 |
| c2c0iA_ |

### PDB 2c0i chain A

Region: 182 - 627
Aligned: 422
Modelled: 442
Confidence: 100.0%
Identity: 39%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2
7 |
| c4fl2A_ |

### PDB 4fl2 chain A

Region: 242 - 621
Aligned: 370
Modelled: 380
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2
8 |
| c2ozoA_ |

### PDB 2ozo chain A

Region: 242 - 627
Aligned: 365
Modelled: 380
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2
9 |
| c3cblA_ |

### PDB 3cbl chain A

Region: 233 - 625
Aligned: 351
Modelled: 379
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide

Phyre2
10 |
| c2j0kB_ |

### PDB 2j0k chain B

Region: 279 - 626
Aligned: 332
Modelled: 348
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.

Phyre2
11 |
| d1qcfa3 |

### PDB 1qcf chain A domain 3

Region: 353 - 621
Aligned: 268
Modelled: 269
Confidence: 100.0%
Identity: 43%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
12 |
| d1opja_ |

### PDB 1opj chain A

Region: 351 - 623
Aligned: 273
Modelled: 273
Confidence: 100.0%
Identity: 44%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
13 |
| c4im2A_ |

### PDB 4im2 chain A

Region: 364 - 622
Aligned: 238
Modelled: 241
Confidence: 100.0%
Identity: 24%
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1

Phyre2
14 |
| c3zzwA_ |

### PDB 3zzw chain A

Region: 363 - 619
Aligned: 256
Modelled: 257
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2

Phyre2
15 |
| d1qpca_ |

### PDB 1qpc chain A

Region: 356 - 622
Aligned: 265
Modelled: 267
Confidence: 100.0%
Identity: 43%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
16 |
| d1k2pa_ |

### PDB 1k2p chain A

Region: 364 - 621
Aligned: 258
Modelled: 258
Confidence: 100.0%
Identity: 62%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2
17 |
| c3qa8H_ |

### PDB 3qa8 chain H

Region: 370 - 611
Aligned: 239
Modelled: 242
Confidence: 100.0%
Identity: 25%
PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2
18 |
| c2ivsA_ |

### PDB 2ivs chain A

Region: 360 - 623
Aligned: 264
Modelled: 264
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain

Phyre2
19 |
| c3pfqA_ |

### PDB 3pfq chain A

Region: 333 - 615
Aligned: 278
Modelled: 283
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii

Phyre2
20 |
| c3g0eA_ |

### PDB 3g0e chain A

Region: 360 - 624
Aligned: 265
Modelled: 265
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: A: PDB Molecule:mast/stem cell growth factor receptor;
PDBTitle: kit kinase domain in complex with sunitinib

Phyre2
21 |
22 |
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117 |
118 |
119 |
| c3o96A_ |

### PDB 3o96 chain A

Region: 2 - 616
Aligned: 333
Modelled: 333
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase;
PDBTitle: crystal structure of human akt1 with an allosteric inhibitor

Phyre2
120 |
121 |
122 |
123 |
124 |
125 |
126 |
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2fo0A_ |
|  | 100.0 | 39 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
2 | c1oplA_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
3 | c1y57A_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
4 | c2h8hA_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
5 | c1k9aB_ |
|  | 100.0 | 40 | PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
6 | c2c0iA_ |
|  | 100.0 | 39 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
7 | c4fl2A_ |
|  | 100.0 | 34 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
8 | c2ozoA_ |
|  | 100.0 | 32 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
9 | c3cblA_ |
|  | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
10 | c2j0kB_ |
|  | 100.0 | 30 | PDB header:transferase Chain: B: PDB Molecule:focal adhesion kinase 1; PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.
11 | d1qcfa3 |
|  | 100.0 | 43 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
12 | d1opja_ |
|  | 100.0 | 44 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
13 | c4im2A_ |
|  | 100.0 | 24 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1; PDBTitle: structure of tank-binding kinase 1
14 | c3zzwA_ |
|  | 100.0 | 35 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2; PDBTitle: crystal structure of the kinase domain of ror2
15 | d1qpca_ |
|  | 100.0 | 43 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
16 | d1k2pa_ |
|  | 100.0 | 62 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
17 | c3qa8H_ |
|  | 100.0 | 25 | PDB header:immune system, signaling protein Chain: H: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta
18 | c2ivsA_ |
|  | 100.0 | 36 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
19 | c3pfqA_ |
|  | 100.0 | 24 | PDB header:transferase Chain: A: PDB Molecule:protein kinase c beta type; PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
20 | c3g0eA_ |
|  | 100.0 | 35 | PDB header:transferase Chain: A: PDB Molecule:mast/stem cell growth factor receptor; PDBTitle: kit kinase domain in complex with sunitinib
21 | c2acxB_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: B: PDB Molecule:g protein-coupled receptor kinase 6; PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp
22 | d1u59a_ |
| not modelled | 100.0 | 34 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
23 | c3nyoB_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: B: PDB Molecule:g protein-coupled receptor kinase 6; PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp
24 | d1lufa_ |
| not modelled | 100.0 | 35 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
25 | c1lufA_ |
| not modelled | 100.0 | 35 | PDB header:transferase Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk; PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation
26 | c2pvfA_ |
| not modelled | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:fibroblast growth factor receptor 2; PDBTitle: crystal structure of tyrosine phosphorylated activated fgf receptor 22 (fgfr2) kinase domain in complex with atp analog and substrate3 peptide
27 | c3c4wB_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: B: PDB Molecule:rhodopsin kinase; PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a
28 | c2vwiC_ |
| not modelled | 100.0 | 28 | PDB header:transferase Chain: C: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structure of the osr1 kinase, a hypertension drug target
29 | c1ym7C_ |
| not modelled | 100.0 | 20 | PDB header:transferase Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1; PDBTitle: g protein-coupled receptor kinase 2 (grk2)
30 | c3ckxA_ |
| not modelled | 100.0 | 28 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 24; PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine
31 | c1koaA_ |
| not modelled | 100.0 | 23 | PDB header:kinase Chain: A: PDB Molecule:twitchin; PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains
32 | c3qa8A_ |
| not modelled | 100.0 | 24 | PDB header:immune system, signaling protein Chain: A: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta
33 | c3c4yA_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:rhodopsin kinase; PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
34 | c3dpkA_ |
| not modelled | 100.0 | 36 | PDB header:transferase Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor; PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor
35 | d2psqa1 |
| not modelled | 100.0 | 36 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
36 | c2psqA_ |
| not modelled | 100.0 | 36 | PDB header:transferase Chain: A: PDB Molecule:fibroblast growth factor receptor 2; PDBTitle: crystal structure of unphosphorylated unactivated wild type2 fgf receptor 2 (fgfr2) kinase domain
37 | c3tkuB_ |
| not modelled | 100.0 | 21 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta; PDBTitle: mrck beta in complex with fasudil
38 | d3bu3a1 |
| not modelled | 100.0 | 36 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
39 | d2j4za1 |
| not modelled | 100.0 | 27 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
40 | c3kulB_ |
| not modelled | 100.0 | 41 | PDB header:transferase Chain: B: PDB Molecule:ephrin type-a receptor 8; PDBTitle: kinase domain of human ephrin type-a receptor 8 (epha8)
41 | d1fmka3 |
| not modelled | 100.0 | 45 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
42 | c4dn5A_ |
| not modelled | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 14; PDBTitle: crystal structure of nf-kb-inducing kinase (nik)
43 | c2c30A_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6; PDBTitle: crystal structure of the human p21-activated kinase 6
44 | d1sm2a_ |
| not modelled | 100.0 | 64 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
45 | c3q5iA_ |
| not modelled | 100.0 | 26 | PDB header:transferase Chain: A: PDB Molecule:protein kinase; PDBTitle: crystal structure of pbanka_031420
46 | c4ebwA_ |
| not modelled | 100.0 | 37 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:focal adhesion kinase 1; PDBTitle: structure of focal adhesion kinase catalytic domain in complex with2 novel allosteric inhibitor
47 | d1t46a_ |
| not modelled | 100.0 | 35 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
48 | c3soaA_ |
| not modelled | 100.0 | 20 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit PDBTitle: full-length human camkii
49 | c3lxkA_ |
| not modelled | 100.0 | 33 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
50 | c4aojA_ |
| not modelled | 100.0 | 40 | PDB header:transferase Chain: A: PDB Molecule:high affinity nerve growth factor receptor; PDBTitle: human trka in complex with the inhibitor az-23
51 | c3plsA_ |
| not modelled | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:macrophage-stimulating protein receptor; PDBTitle: ron in complex with ligand amp-pnp
52 | d1mp8a_ |
| not modelled | 100.0 | 36 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
53 | c4fijA_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4; PDBTitle: catalytic domain of human pak4
54 | c3sxrA_ |
| not modelled | 100.0 | 57 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib
55 | d1p4oa_ |
| not modelled | 100.0 | 38 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
56 | c3lvpD_ |
| not modelled | 100.0 | 41 | PDB header:transferase Chain: D: PDB Molecule:insulin-like growth factor 1 receptor; PDBTitle: crystal structure of bisphosphorylated igf1-r kinase domain (2p) in2 complex with a bis-azaindole inhibitor
57 | d1fgka_ |
| not modelled | 100.0 | 36 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
58 | d1jpaa_ |
| not modelled | 100.0 | 39 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
59 | c3l9pA_ |
| not modelled | 100.0 | 41 | PDB header:transferase Chain: A: PDB Molecule:anaplastic lymphoma kinase; PDBTitle: crystal structure of the anaplastic lymphoma kinase catalytic domain
60 | c4fieB_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase pak 4; PDBTitle: full-length human pak4
61 | c2bujA_ |
| not modelled | 100.0 | 20 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 16; PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine
62 | c3eygA_ |
| not modelled | 100.0 | 32 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
63 | c1yvjA_ |
| not modelled | 100.0 | 31 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: crystal structure of the jak3 kinase domain in complex with2 a staurosporine analogue
64 | c2jamB_ |
| not modelled | 100.0 | 25 | PDB header:transferase Chain: B: PDB Molecule:calcium/calmodulin-dependent protein kinase type PDBTitle: crystal structure of human calmodulin-dependent protein2 kinase i g
65 | c3cc6A_ |
| not modelled | 100.0 | 34 | PDB header:transferase Chain: A: PDB Molecule:protein tyrosine kinase 2 beta; PDBTitle: crystal structure of kinase domain of protein tyrosine kinase 2 beta2 (ptk2b)
66 | c2wtkC_ |
| not modelled | 100.0 | 23 | PDB header:transferase/metal-binding protein Chain: C: PDB Molecule:serine/threonine-protein kinase 11; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
67 | d1xbba_ |
| not modelled | 100.0 | 37 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
68 | c3fupB_ |
| not modelled | 100.0 | 31 | PDB header:transferase Chain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
69 | d1yhwa1 |
| not modelled | 100.0 | 24 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
70 | c3lijA_ |
| not modelled | 100.0 | 26 | PDB header:transferase Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp
71 | c2a1aB_ |
| not modelled | 100.0 | 24 | PDB header:protein synthesis/transferase Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein PDBTitle: pkr kinase domain-eif2alpha complex
72 | d1mqba_ |
| not modelled | 100.0 | 40 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
73 | c2w1iB_ |
| not modelled | 100.0 | 31 | PDB header:transferase Chain: B: PDB Molecule:jak2; PDBTitle: structure determination of aurora kinase in complex with2 inhibitor
74 | c3fbvL_ |
| not modelled | 100.0 | 22 | PDB header:transferase, hydrolase Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1
75 | d1uwha_ |
| not modelled | 100.0 | 32 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
76 | c3d9vA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:rho-associated protein kinase 1; PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil
77 | c3vw6B_ |
| not modelled | 100.0 | 28 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
78 | c2j51A_ |
| not modelled | 100.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
79 | d1phka_ |
| not modelled | 100.0 | 21 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
80 | c4eutA_ |
| not modelled | 100.0 | 24 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1; PDBTitle: structure of bx-795 complexed with unphosphorylated human tbk1 kinase-2 uld domain
81 | c3d4qA_ |
| not modelled | 100.0 | 32 | PDB header:transferase Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
82 | c2clqA_ |
| not modelled | 100.0 | 27 | PDB header:transferase Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5
83 | c2bmcD_ |
| not modelled | 100.0 | 29 | PDB header:transferase Chain: D: PDB Molecule:serine threonine-protein kinase 6; PDBTitle: aurora-2 t287d t288d complexed with pha-680632
84 | c3p23B_ |
| not modelled | 100.0 | 21 | PDB header:hydrolase, transferase Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp
85 | c2y7jB_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain, PDBTitle: structure of human phosphorylase kinase, gamma 2
86 | c3v5qB_ |
| not modelled | 100.0 | 37 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
87 | d2jfla1 |
| not modelled | 100.0 | 25 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
88 | d1fvra_ |
| not modelled | 100.0 | 38 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
89 | c3lxnA_ |
| not modelled | 100.0 | 30 | PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
90 | c3dfaA_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920; PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum
91 | c2qg5D_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase; PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840
92 | c2qobA_ |
| not modelled | 100.0 | 39 | PDB header:transferase Chain: A: PDB Molecule:ephrin receptor; PDBTitle: human epha3 kinase domain, base structure
93 | c2vd5A_ |
| not modelled | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:dmpk protein; PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii
94 | c2a27B_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: B: PDB Molecule:death-associated protein kinase 2; PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit
95 | c3hztA_ |
| not modelled | 100.0 | 27 | PDB header:transferase Chain: A: PDB Molecule:calcium-dependent protein kinase 3; PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860
96 | c3k54A_ |
| not modelled | 100.0 | 62 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
97 | c1xkkA_ |
| not modelled | 100.0 | 34 | PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
98 | d1xkka_ |
| not modelled | 100.0 | 34 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
99 | d1rjba_ |
| not modelled | 100.0 | 39 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
100 | d1ckia_ |
| not modelled | 100.0 | 18 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
101 | d1jksa_ |
| not modelled | 100.0 | 24 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
102 | c3comB_ |
| not modelled | 100.0 | 27 | PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase 4; PDBTitle: crystal structure of mst1 kinase
103 | c2wqmA_ |
| not modelled | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase nek7; PDBTitle: structure of apo human nek7
104 | c2pziA_ |
| not modelled | 100.0 | 14 | PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
105 | c2cgvA_ |
| not modelled | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase chk1; PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening
106 | c1mruB_ |
| not modelled | 100.0 | 26 | PDB header:transferase Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb; PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb.
107 | d1koba_ |
| not modelled | 100.0 | 24 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
108 | c2chlA_ |
| not modelled | 100.0 | 18 | PDB header:transferase Chain: A: PDB Molecule:casein kinase i isoform gamma-3; PDBTitle: structure of casein kinase 1 gamma 3
109 | d1o6ya_ |
| not modelled | 100.0 | 26 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
110 | c4g3dE_ |
| not modelled | 100.0 | 25 | PDB header:transferase Chain: E: PDB Molecule:nf-kappa-beta-inducing kinase; PDBTitle: crystal structure of human nf-kappab inducing kinase (nik)
111 | c4e1zA_ |
| not modelled | 100.0 | 31 | PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor
112 | c2bdwB_ |
| not modelled | 100.0 | 24 | PDB header:transferase Chain: B: PDB Molecule:hypothetical protein k11e8.1d; PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii
113 | c2x4fA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:myosin light chain kinase family member 4; PDBTitle: the crystal structure of the human myosin light chain2 kinase loc340156.
114 | d1nvra_ |
| not modelled | 100.0 | 21 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
115 | c2ya9A_ |
| not modelled | 100.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:death-associated protein kinase 2; PDBTitle: crystal structure of the autoinhibited form of mouse dapk2
116 | c1xjdA_ |
| not modelled | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:protein kinase c, theta type; PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution
117 | d1xjda_ |
| not modelled | 100.0 | 22 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
118 | c3zosA_ |
| not modelled | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:epithelial discoidin domain-containing receptor 1; PDBTitle: structure of the ddr1 kinase domain in complex with ponatinib
119 | c3o96A_ |
|  | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
120 | d1koaa2 |
| not modelled | 100.0 | 23 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit

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