|   |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
|
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | E | W | E | R | P | R | S | E | F | V | L | R | R | K | L | G | E | G | F | F | G | E | V | W | E | G | L | W | L | G | S | I | P | V | A | V | K | V | I | K | S | . |
. |
. |
A | D | M | K | L | A | D | L | T | K | E | I | E | A | L |
| Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   | . | . |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
| Template Sequence |   |
D | D | W | E | I | P | D | G | Q | I | T | V | G | Q | R | I | G | S | G | S | F | G | T | V | Y | K | G | K | W | H | G | . |
. |
D | V | A | V | K | M | L | N | V | T | A | P | T | P | Q | Q | L | Q | A | F | K | N | E | V | G | V | L |
| Template Known Secondary structure |   |
|
|
| B |
|
| T | T |
|
|
|
|
| S |  |  |  |  |
| S | S |
|  |  |  |  |  |  | S | S | S | . | . |  |  |  |  |  |  |
|
|
| S | S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
447 | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | |
|
. | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . |
|   |
|   |   |
282 | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | S | L | R | H | E | R | L | I | R | L | H | A | I | C | S | L | G | E | P | V | Y | I | V | T | E | L | M | G | K | G | N | L | Q | V | Y | L | G | S | S | E | G | K | A | L | S | L | P | H | L | L | G | F | A | C | Q | V | A | E | G |
| Query Conservation |   |
  |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   | . |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
R | K | T | R | H | V | N | I | L | L | F | M | G | Y | S | T | A | P | Q | L | . |
A | I | V | T | Q | W | C | E | G | S | S | L | Y | H | H | L | H | I | I | . |
E | T | K | F | E | M | I | K | L | I | D | I | A | R | Q | T | A | Q | G |
| Template Known Secondary structure |   |
T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |
| S | S | S |
| . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | T | S | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
505 | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | |
. | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | |
. | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . |
|   |
|   |   |
342 | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | S | Y | L | E | E | R | R | V | V | H | R | D | L | A | A | R | N | V | L | V | G | D | D | L | T | C | K | V | A | D | F | G | L | A | R | L | L | K | D | D | V | Y | S | P | S | S | G | S | K | I | P | V | K | W | T | A | P | E | A |
| Query Conservation |   |
|   |
|
|
|   |   |   |   |
|
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|
|   |
| Template Sequence |   |
M | D | Y | L | H | A | K | S | I | I | H | R | D | L | K | S | N | N | I | F | L | H | E | D | L | T | V | K | I | G | D | F | G | L | A | T | V | L | S | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | I | L | W | M | A | P | E | V |
| Template Known Secondary structure |   |
 |  |  |  |  |  | T | T |
|
|
| S |
|
|
| G | G | G |  |  |  |  | T | T | S | S |  |  |  |
|
|
|
|
| S |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
| G | G | G |
|
|  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
563 | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 610 | . |
|   |
|   |   |
402 | . | |
|
|
. | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
. | 440 | . | . | . | . | . | . | . | . | . | 450 | . | |
|
|
|
. | . |
| Predicted Secondary structure |   |
 |  | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  | . |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
| Query SS confidence |   |
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
| Query Sequence |   |
A | N | . |
. |
. |
Y | R | V | F | S | Q | K | S | D | V | W | S | F | G | I | L | L | Y | E | V | F | T | Y | G | Q | C | P | Y | E | G | M | T | N | H | E | . |
T | L | Q | Q | I | S | R | G | Y | R | L | P | R | . |
. |
. |
. |
P | A |
| Query Conservation |   |
|   | . | . | . |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
| . |   |   |   |   |
|   |   |   |   |
|   |   |   | . | . | . | . |
|   |
| Alig confidence |   |
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|
|
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
I | R | M | Q | D | K | N | P | Y | S | F | Q | S | D | V | Y | A | F | G | I | V | L | Y | E | L | M | T | . |
G | Q | L | P | Y | S | N | I | N | N | R | D | Q | I | I | F | M | V | G | R | G | Y | L | S | P | D | L | S | K | V | R | S |
| Template Known Secondary structure |   |
 | T | T |
| S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | T | S |
|
|
|
| G | G | G | S |
| T |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
624 | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | |
. | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . |
|   |
|   |   |
454 | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | C | P | A | E | V | Y | V | L | M | V | E | C | W | K | G | S | P | E | E | R | P | T | F | A | I | L | R | E | K | L | N | A | I | N | R | R | L |
| Query Conservation |   |
  |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |
|
| Template Sequence |   |
N | C | P | K | A | M | K | R | L | M | A | E | C | L | K | K | K | R | D | E | R | P | L | F | P | Q | I | L | A | S | I | E | L | L | A | R | S | L |
| Template Known Secondary structure |   |
T |
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
683 | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 |
|   |