Job Description Q62270 Confidence 100.00% Date Tue Jul 30 13:00:53 BST 2013 Rank 99 Aligned Residues 264 % Identity 37% Template c4e1zA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor Resolution 2.50 Å

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		224	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.						.	.	.	.	260	.	.	.	.	.	.	.	.	.	270			.	.	.	.	.	.
Predicted Secondary structure																																		.	.	.	.	.																.	.
Query SS confidence																																		.	.	.	.	.																.	.
Query Sequence		Q	D	E	W	E	R	P	R	S	E	F	V	L	R	R	K	L	G	E	G	F	F	G	E	V	W	E	G	L	W	L	G	.	.	.	.	.	S	I	P	V	A	V	K	V	I	K	S	A	D	M	K	.	.	L	A	D	L	T	K
Query Conservation																																		.	.	.	.	.																.	.
Alig confidence																																		.	.	.	.	.																.	.
Template Conservation
Template Sequence		S	D	P	T	V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	E	G	C	G	P	Q	L	R	S	G	W	Q	R
Template Known Secondary structure				T	T	B			G	G	G											S	S										T	T			S	S											T	T
Template Predicted Secondary structure
Template SS confidence
		883	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.
		277	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	I	E	A	L	K	S	L	R	H	E	R	L	I	R	L	H	A	I	C	S	L	G	E	P	V	Y	I	V	T	E	L	M	G	K	G	N	L	Q	V	Y	L	G	S	S	E	G	K	A	L	S	L	P	H	L	L	G	F	A	C
Query Conservation
Alig confidence																																			.												.	.	.
Template Conservation																																			.												.	.	.
Template Sequence		E	I	E	I	L	R	T	L	Y	H	E	H	I	V	K	Y	K	G	C	C	E	D	K	S	V	Q	L	V	M	E	Y	V	P	.	L	G	S	L	R	D	Y	L	P	R	H	.	.	.	C	V	G	L	A	Q	L	L	L	F	A	Q
Template Known Secondary structure												T	T	B																				T	.	T							G	G	G	S	.	.	.
Template Predicted Secondary structure																																			.												.	.	.
Template SS confidence
		943	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.		.	.	.	.	980	.	.	.	.	.	.				.	.	.	990	.	.	.	.	.	.	.	.
		337	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.			.	.	.
Predicted Secondary structure																																																									.	.
Query SS confidence																																																									.	.
Query Sequence		Q	V	A	E	G	M	S	Y	L	E	E	R	R	V	V	H	R	D	L	A	A	R	N	V	L	V	G	D	D	L	T	C	K	V	A	D	F	G	L	A	R	L	L	K	D	D	V	Y	S	P	S	S	G	S	K	.	.	I	P	V
Query Conservation																																																									.	.
Alig confidence																																																									.	.
Template Conservation
Template Sequence		Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	A	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	Y	R	V	R	E	D	G	D	S	P	V
Template Known Secondary structure													T	T				S			S	G	G	G					G	G	G								T	T						T	T		S								S	S	S		G
Template Predicted Secondary structure
Template SS confidence
		1002	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.
		395	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.																.	.	.	.	.	.
Predicted Secondary structure																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	W	T	A	P	E	A	A	N	Y	R	V	F	S	Q	K	S	D	V	W	S	F	G	I	L	L	Y	E	V	F	T	Y	G	Q	C	P	Y	E	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	T	N	H	E	T
Query Conservation																																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																	.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																	.
Template Sequence		F	W	Y	A	P	E	C	L	K	E	C	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	Y	C	D	S	N	Q	S	P	H	T	K	F	T	E	L	I	G	H	T	Q	G	Q	M	T	V	L	R	L
Template Known Secondary structure		G	G								S																					T	.	T	T		T	T	S	S											S
Template Predicted Secondary structure																																	.
Template SS confidence
		1062	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120
		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	Q	Q	I	S	R	G	Y	R	L	P	R	P	A	V	C	P	A	E	V	Y	V	L	M	V	E	C	W	K	G	S	P	E	E	R	P	T	F	A	I	L	R	E	K	L	N	A	I	N	R	R	L	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	E	L	L	E	R	G	E	R	L	P	R	P	D	R	C	P	C	E	I	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	Q	N	L	V	P	I	L	Q	T	A	Q	E	K	Y	Q
Template Known Secondary structure								T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1121	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D