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Job DescriptionQ62270
Confidence100.00%DateTue Jul 30 13:00:53 BST 2013
Rank109Aligned Residues265
% Identity37%Templatec3zosA_
PDB info PDB header:transferaseChain: A: PDB Molecule:epithelial discoidin domain-containing receptor 1; PDBTitle: structure of the ddr1 kinase domain in complex with ponatinib
Resolution1.92 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   226...230.........240.........250..... ....260........
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Query Sequence  EWERPRSEFVLRRKLGEGFFGEVWEGLWLG. . . . . . . . . . . . . . . . . SIPVAVKVIKSAD
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Template Sequence  RVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDA
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GGGTTSSGGGG
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   602.......610.........620.........630.........640.........650.........660.
 
   269270.. .......280.........290.........300.........310.........320.
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Query Sequence  MKLA. . DLTKEIEALKSLRHERLIRLHAICSLGEPVYIVTELMGKGNLQVYLGSS. . . . .
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Template Sequence  TKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDA
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   662.......670.........680.........690.........700.........710.........720.
 
   322.......330.........340.........350.........360.........370.........
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Query Sequence  . EGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLVGDDLTCKVADFGLARLL.
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Template Sequence  AQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLY
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   733......740.........750.........760.........770.........780.........790..
 
   380.........390.........400.........410.........420..... ....430........
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Query Sequence  KDDVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFT. YGQCPYEGMTNHE
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Template Sequence  AGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQ
Template Known Secondary structure  GGG
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   793......800.........810.........820.........830.........840.........850..
 
   439440...... ...450.........460.........470.........480.........490
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Query Sequence  TLQQISRG. . . . . . . YRLPRPAVCPAEVYVLMVECWKGSPEERPTFAILREKLNAINRR
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Template Sequence  VIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALN
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   853......860.........870.........880.........890.........900.........910.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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