|   |   |
254 | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | G | S | I | P | V | A | V | K | V | I | K | S | A | D | M | K | L | A | D | L | T | K | E | I | E | A | L | K | S | L | . |
R | H | E | R | L | I | R | L | H | A | I | C | S | L | G | E | P | V | Y | I | V | T | E | L | M | G | K | G |
| Query Conservation |   |
  |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| . |   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |
|
| . | . | . | . | . | . | . |   |   |   |   |
|
|   |
|
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   | . | . | . | . | . | . |   |
|
|
|
|   |   |   |   |
|
| Template Sequence |   |
V | H | N | M | E | Y | A | V | K | V | I | D | . |
. |
. |
. |
. |
. |
. |
K | P | S | E | E | I | E | I | L | L | R | Y | G | Q | H | P | N | I | I | T | L | K | D | V | Y | . |
. |
. |
. |
. |
. |
D | L | V | T | E | L | M | R | G | G |
| Template Known Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  | T | T | S | T | T | B |
|
|  |  |  |
|
| . | . | . | . | . | . |
|
|  |  |
|
|
|
| S |
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
436 | . | . | . | 440 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 480 | . | . |
|   |
|   |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | L | Q | V | Y | L | G | S | S | E | G | K | A | L | S | L | P | H | L | L | G | F | A | C | Q | V | A | E | G | M | S | Y | L | E | E | R | R | V | V | H | R | D | L | A | A | R | N | V | L | V | G | D | D | L | T | C | K | V | A | D |
| Query Conservation |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |   |
|
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
| Alig confidence |   |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | L | L | D | K | I | . |
. |
L | R | Q | K | F | F | S | E | R | E | A | S | F | V | L | H | T | I | G | K | T | V | E | Y | L | H | S | Q | G | V | V | H | R | D | L | K | P | S | N | I | L | Y | V | D | E | S | G | N | P | E | C | L |
| Template Known Secondary structure |   |
B |  |  |  |  |  | . | . | T | S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
|
| G | G | G |  |  |  | S | S | T | T |
|
| G | G | G |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
496 | . | . | . | 500 | . | |
|
. | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . |
|   |
|   |   |
373 | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | |
| Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| Query Sequence |   |
F | G | L | A | R | L | L | K | D | D | V | Y | S | P | S | S | G | S | K | I | P | V | K | W | T | A | P | E | A | A | N | Y | R | V | F | S | Q | K | S | D | V | W | S | F | G | I | L | L | Y | E | V | F | T | Y | G | Q | C | P | Y | . |
| Query Conservation |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   | . |
| Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
| Template Conservation |   |
  |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   | . |
|   |   |
|   |   |
| Template Sequence |   |
R | I | C | D | F | . |
. |
. |
G | F | A | K | Q | L | R | A | E | N | G | L | L | M | T | P | C | Y | T | E | V | L | K | R | Q | G | Y | D | E | G | C | D | I | W | S | L | G | I | L | L | Y | T | M | L | A | . |
G | Y | T | P | F | A |
| Template Known Secondary structure |   |
 |  |
|
|
| . | . | . | T | T |
|  |  |
| B |
| S | S |
|
| B |
|
| G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| Template Predicted Secondary structure |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
554 | . | . | . | . | |
|
|
. | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | |
. | . | . | . | . | . |
|   |
|   |   |
|
|
432 | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | |
|
|
. | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . |
| Predicted Secondary structure |   |
. | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
E | G | M | T | N | H | E | T | L | Q | Q | I | S | R | G | Y | R | L | P | R | P | . |
. |
. |
A | V | C | P | A | E | V | Y | V | L | M | V | E | C | W | K | G | S | P | E | E | R | P | T | F | A | I | L | R | E |
| Query Conservation |   |
. | . |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |
| . | . | . |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
N | G | P | S | D | T | P | E | E | I | L | T | R | I | G | S | G | K | F | T | L | S | G | G | N | W | N | T | V | S | E | T | A | K | D | L | V | S | K | M | L | H | V | D | P | H | Q | R | L | T | A | K | Q | V | L | Q |
| Template Known Secondary structure |   |
S | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
| S | G | G | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  | S |
| S | S | T | T | S | S |
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
616 | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . |
|   |