Job Description Q62270 Confidence 100.00% Date Tue Jul 30 13:00:53 BST 2013 Rank 216 Aligned Residues 275 % Identity 27% Template c3h9rA_ PDB info PDB header:isomerase/protein kinase Chain: A: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the kinase domain of type i activin receptor2 (acvr1) in complex with fkbp12 and dorsomorphin Resolution 2.35 Å

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		192	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	S	L	D	A	L	L	A	Y	Y	K	T	N	W	K	L	I	Q	N	P	L	L	Q	P	C	I	P	Q	I	P	L	V	Q	D	E	W	E	R	P	R	S	E	F	V	L	R	R	K	L	G	E	G	F	F	G	E	V	W	E	G
Query Conservation
Alig confidence																										.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																										.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		S	T	L	A	D	L	L	D	H	S	C	T	S	G	S	G	S	G	L	P	F	L	V	Q	.	.	.	.	.	.	.	.	.	.	.	.	R	T	V	A	R	Q	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G
Template Known Secondary structure										T			S	T	T			S	S	S						.	.	.	.	.	.	.	.	.	.	.	.					T	T											T	T
Template Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		178	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.													.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.
		252	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.		.	300	.	.	.	.	.	.	.	.	.	310
Predicted Secondary structure																																																	.
Query SS confidence																																																	.
Query Sequence		L	W	L	G	S	I	P	V	A	V	K	V	I	K	S	A	D	M	K	L	A	D	L	T	K	E	I	E	A	L	K	S	L	R	H	E	R	L	I	R	L	H	A	I	C	S	L	.	G	E	P	V	Y	I	V	T	E	L	M	G
Query Conservation																																																	.
Alig confidence						.																																											.
Template Conservation						.
Template Sequence		S	W	Q	G	.	E	N	V	A	V	K	I	F	S	S	R	D	E	K	S	W	F	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L	G	F	I	A	S	D	M	T	S	S	T	Q	L	W	L	I	T	H	Y	H	E
Template Known Secondary structure				T	T	.										G	G	G														S					T	T	B																						T
Template Predicted Secondary structure						.
Template SS confidence
		226	.	.	.		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.
		311	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.									.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.
Predicted Secondary structure																																						.	.	.	.	.	.	.	.
Query SS confidence																																						.	.	.	.	.	.	.	.
Query Sequence		K	G	N	L	Q	V	Y	L	G	S	S	E	G	K	A	L	S	L	P	H	L	L	G	F	A	C	Q	V	A	E	G	M	S	Y	L	E	.	.	.	.	.	.	.	.	E	R	R	V	V	H	R	D	L	A	A	R	N	V	L	V
Query Conservation																																						.	.	.	.	.	.	.	.
Alig confidence													.	.	.																							.	.	.	.	.	.	.	.
Template Conservation													.	.	.
Template Sequence		M	G	S	L	Y	D	Y	L	Q	L	T	.	.	.	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V
Template Known Secondary structure		T		B									.	.	.		B																							B		S	T	T		B						S				G	G	G
Template Predicted Secondary structure													.	.	.
Template SS confidence
		288	.	290	.	.	.	.	.	.	.	.				.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
		363	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	D	D	L	T	C	K	V	A	D	F	G	L	A	R	L	L	K	D	D	V	Y	S	P	S	S	G	S	K	I	P	V	K	W	T	A	P	E	A	A	N	Y	R	V	F	S	Q	K	S	D	V	W	S	F	G	I	L	L	Y	E
Query Conservation
Alig confidence																		.	.	.	.
Template Conservation																		.	.	.	.
Template Sequence		K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V	M	.	.	.	.	H	R	V	G	T	K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E
Template Known Secondary structure			T	T	S								T	T				.	.	.	.						G	G	G							T	T				T	T
Template Predicted Secondary structure																		.	.	.	.
Template SS confidence
		345	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360					.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
		423	.	.	.	.	.	.	430	.	.	.	.	.	.	.																.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.							.	.	.	.	.	460	.
Predicted Secondary structure																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Query SS confidence																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Query Sequence		V	F	T	Y	G	Q	C	P	Y	E	G	M	T	N	H	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	T	L	Q	Q	I	S	R	G	Y	R	L	P	R	P	A	V	.	.	.	.	.	.	C	P	A	E	V	Y	V
Query Conservation																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Alig confidence					.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Template Conservation					.
Template Sequence		V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V	V	P	N	D	P	S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K
Template Known Secondary structure				T	.	T	B		B	T	T	B							T	T	T	T	T	S		S	S											T	T	S								G	G	G	G	G	S
Template Predicted Secondary structure					.
Template SS confidence
		414	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.
		462	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	M	V	E	C	W	K	G	S	P	E	E	R	P	T	F	A	I	L	R	E	K	L	N	A	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T	L	T	K	I
Template Known Secondary structure					T	T			S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		473	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D