Job Description Q62270 Confidence 100.00% Date Tue Jul 30 13:00:53 BST 2013 Rank 72 Aligned Residues 251 % Identity 34% Template c3d4qA_ PDB info PDB header:transferase Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase Resolution 2.80 Å

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		225	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.				.	.	.	.	.	.	.	280	.
Predicted Secondary structure																																																		.	.	.
Query SS confidence																																																		.	.	.
Query Sequence		D	E	W	E	R	P	R	S	E	F	V	L	R	R	K	L	G	E	G	F	F	G	E	V	W	E	G	L	W	L	G	S	I	P	V	A	V	K	V	I	K	S	A	D	M	K	L	A	.	.	.	D	L	T	K	E	I	E	A	L
Query Conservation																																																		.	.	.
Alig confidence																																		.	.															.	.	.
Template Conservation																																		.	.
Template Sequence		D	D	W	E	I	P	D	G	Q	I	T	V	G	Q	R	I	G	S	G	S	F	G	T	V	Y	K	G	K	W	H	G	D	.	.	V	A	V	K	M	L	N	V	T	A	P	T	P	Q	Q	L	Q	A	F	K	N	E	V	G	V	L
Template Known Secondary structure					B			T	T												T	T								S	S	S		.	.								S	S	S
Template Predicted Secondary structure																																		.	.
Template SS confidence
		448	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.			480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.
		282	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	S	L	R	H	E	R	L	I	R	L	H	A	I	C	S	L	G	E	P	V	Y	I	V	T	E	L	M	G	K	G	N	L	Q	V	Y	L	G	S	S	E	G	K	A	L	S	L	P	H	L	L	G	F	A	C	Q	V	A	E	G
Query Conservation
Alig confidence																		.																								.
Template Conservation																		.																								.
Template Sequence		R	K	T	R	H	V	N	I	L	L	F	M	G	Y	S	T	.	K	P	Q	L	A	I	V	T	Q	W	C	E	G	S	S	L	Y	H	H	L	H	I	I	.	E	T	K	F	E	M	I	K	L	I	D	I	A	R	Q	T	A	Q	G
Template Known Secondary structure		T	T				T	T	B									.	S	S	S									S	S		B							T	S	.
Template Predicted Secondary structure																		.																								.
Template SS confidence
		506	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.		.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.		.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.
		342	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	S	Y	L	E	E	R	R	V	V	H	R	D	L	A	A	R	N	V	L	V	G	D	D	L	T	C	K	V	A	D	F	G	L	A	R	L	L	K	D	D	V	Y	S	P	S	S	G	S	K	I	P	V	K	W	T	A	P	E	A
Query Conservation
Alig confidence																																								.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																								.	.	.	.	.	.	.	.	.	.	.
Template Sequence		M	D	Y	L	H	A	K	S	I	I	H	R	D	L	K	S	N	N	I	F	L	H	E	D	L	T	V	K	I	G	D	F	G	L	A	T	V	L	.	.	.	.	.	.	.	.	.	.	.	S	G	S	I	L	W	M	A	P	E	V
Template Known Secondary structure								T	T		B		S			S	G	G	G					T	T	T								T	T		B			.	.	.	.	.	.	.	.	.	.	.					T	T
Template Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		564	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.												.	.	.	.	.	.	.	.	610	.	.
		402	.	.	.	.				.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.		.	440	.	.	.	.	.	.	.	.	.	450					.	.	.
Predicted Secondary structure							.	.	.																																	.													.	.	.	.
Query SS confidence							.	.	.																																	.													.	.	.	.
Query Sequence		A	N	Y	R	V	.	.	.	F	S	Q	K	S	D	V	W	S	F	G	I	L	L	Y	E	V	F	T	Y	G	Q	C	P	Y	E	G	M	T	N	H	E	.	T	L	Q	Q	I	S	R	G	Y	R	L	P	.	.	.	.	R	P	A
Query Conservation							.	.	.																																	.													.	.	.	.
Alig confidence							.	.	.																				.													.													.	.	.	.
Template Conservation																													.
Template Sequence		I	R	M	Q	D	K	N	P	Y	S	F	Q	S	D	V	Y	A	F	G	I	V	L	Y	E	L	M	T	.	G	Q	L	P	Y	S	N	I	N	N	R	D	Q	I	I	F	M	V	G	R	G	Y	L	S	P	D	L	S	K	V	R	S
Template Known Secondary structure			T	T		S	S				S																		.	S	S		T	T	T	T														T	S					G	G	G	S		T
Template Predicted Secondary structure																													.
Template SS confidence
		625	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.		.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.
		454	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	C	P	A	E	V	Y	V	L	M	V	E	C	W	K	G	S	P	E	E	R	P	T	F	A	I	L	R	E	K	L	N	A	I	N	R	R	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	C	P	K	A	M	K	R	L	M	A	E	C	L	K	K	K	R	D	E	R	P	L	F	P	Q	I	L	A	S	I	E	L	L	A	R	S	L
Template Known Secondary structure		T	S												T		S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		684	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D