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Job DescriptionQ62270
Confidence100.00%DateTue Jul 30 13:00:53 BST 2013
Rank138Aligned Residues238
% Identity21%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   231........240.........250... ......260..... ....270.........280.....
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Query Sequence  RSEFVLRRKLGEGFFGEVWEGLW. LGSIPVAVKVIK. . . . SADMKLADLTKEIEALKSLR
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Template Sequence  PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD
Template Known Secondary structure  GGG
SS
TTT

TT
T

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   7980.........90.........100.........110.........120.........130........
 
   286...290.........300.........310.........320.........330.........340.....
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Query Sequence  HERLIRLHAICSLGEPVYIVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYL
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Template Sequence  HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIG. . SFDETCTRFYTAEIVSALEYL
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TTB


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   139140.........150.........160.........170..... ....180.........190......
 
   346...350.........360.........370.........380.........390.........400.....
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Query Sequence  EERRVVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWTAPEAANYR
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Template Sequence  HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . . . . . . FVGTAQYVSPELLTEK
Template Known Secondary structure  TT




TTT
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   197..200.........210.........220.........230 .........240......
 
   406...410.........420.........430.........440.........450.........460.....
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Query Sequence  VFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQISRGYRLPRPAVCPAEVYVLMVE
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Template Sequence  SACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVEK
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   258.260.........270....... ..280.........290........ .300.........310.....
 
   466...470.........480..
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Query Sequence  CWKGSPEERPTFAILRE
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Template Sequence  LLVLDATKRLGCEEMEG
Template Known Secondary structure  TS
SSTTSSTTSGGGTT
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   316...320.........330..
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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