Job Description Q62270 Confidence 100.00% Date Tue Jul 30 13:00:53 BST 2013 Rank 1 Aligned Residues 442 % Identity 37% Template c2fo0A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase Resolution 2.27 Å Model Dimensions (Å) X:77.340 Y:71.887 Z:47.364

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		41	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100
Predicted Secondary structure
Query SS confidence
Query Sequence		P	E	Q	A	A	A	V	E	P	C	S	F	P	A	P	R	A	R	L	F	R	A	L	Y	D	F	T	A	R	C	A	E	E	L	S	V	S	R	G	D	R	L	Y	A	L	K	E	E	G	D	Y	I	F	A	Q	R	L	S	G	P
Query Conservation
Alig confidence																																																												.
Template Conservation																																																												.
Template Sequence		A	R	W	N	K	E	N	L	L	A	G	P	S	E	N	D	P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	T	.	K
Template Known Secondary structure							T	T	T	T			G	G	G	S		T	T					S	S		B				S	T	T	B			B		T	T										T	T	S	S							.	T
Template Predicted Secondary structure																																																												.
Template SS confidence
		65	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.		.
		101	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
Predicted Secondary structure
Query SS confidence
Query Sequence		P	S	T	G	L	V	P	V	T	Y	L	A	K	A	T	P	E	P	P	S	D	Q	P	W	Y	F	S	G	I	S	R	A	Q	A	Q	Q	L	L	L	S	P	A	N	A	P	G	A	F	L	I	R	P	S	E	S	S	I	G	G	Y
Query Conservation
Alig confidence																	.	.																									.	.
Template Conservation																	.	.																									.	.
Template Sequence		N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	.	.	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	.	.	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R
Template Known Secondary structure		T							G	G	G				T	T	.	.	S	G	G	G	S	T	T														T	S	S	S	.	.		T	T								S	S	S	T	T
Template Predicted Secondary structure																	.	.																									.	.
Template SS confidence
		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.			140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.			.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220
Predicted Secondary structure
Query SS confidence
Query Sequence		S	L	S	V	R	A	Q	A	K	V	C	H	Y	R	I	C	M	A	P	S	G	S	L	Y	L	Q	E	G	Q	L	F	P	S	L	D	A	L	L	A	Y	Y	K	T	N	W	K	L	I	Q	N	P	L	L	Q	P	C	I	P	Q	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	I	S	L	R	Y	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N
Template Known Secondary structure								T	T											T	T	S				S	S	T	T			B	S	S													T	T	S	S	S
Template Predicted Secondary structure
Template SS confidence
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
									221	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.		.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.
Predicted Secondary structure		.	.	.	.	.	.	.																																				.
Query SS confidence		.	.	.	.	.	.	.																																				.
Query Sequence		.	.	.	.	.	.	.	P	L	V	Q	D	E	W	E	R	P	R	S	E	F	V	L	R	R	K	L	G	E	G	F	F	G	E	V	W	E	G	L	W	L	G	.	S	I	P	V	A	V	K	V	I	K	S	A	D	M	K	L	A
Query Conservation		.	.	.	.	.	.	.																																				.
Alig confidence		.	.	.	.	.	.	.																																				.
Template Conservation
Template Sequence		K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	E
Template Known Secondary structure						S	S	S		S	S	T	T			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T										T	T	S
Template Predicted Secondary structure
Template SS confidence
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
		273	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	L	T	K	E	I	E	A	L	K	S	L	R	H	E	R	L	I	R	L	H	A	I	C	S	L	G	E	P	V	Y	I	V	T	E	L	M	G	K	G	N	L	Q	V	Y	L	G	S	S	E	G	K	A	L	S	L	P	H	L	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L
Template Known Secondary structure																T	T	B									S	S	S	S									T	T		B								S		T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		301	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
		333	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	F	A	C	Q	V	A	E	G	M	S	Y	L	E	E	R	R	V	V	H	R	D	L	A	A	R	N	V	L	V	G	D	D	L	T	C	K	V	A	D	F	G	L	A	R	L	L	K	D	D	V	Y	S	P	S	S	G	S	K	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F
Template Known Secondary structure																	T	T				S			S	G	G	G					G	G	G							T	T						S	S							T	T
Template Predicted Secondary structure
Template SS confidence
		361	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	V	K	W	T	A	P	E	A	A	N	Y	R	V	F	S	Q	K	S	D	V	W	S	F	G	I	L	L	Y	E	V	F	T	Y	G	Q	C	P	Y	E	G	M	T	N	H	E	T	L	Q	Q	I	S	R	G	Y	R	L	P	R	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M	E	R	P
Template Known Secondary structure			G	G	G																													T	T	S			S	S	T	T												T	T
Template Predicted Secondary structure
Template SS confidence
		421	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
		453	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	V	C	P	A	E	V	Y	V	L	M	V	E	C	W	K	G	S	P	E	E	R	P	T	F	A	I	L	R	E	K	L	N	A	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M
Template Known Secondary structure		T	T													T		S	S	G	G	G	S												T	S
Template Predicted Secondary structure
Template SS confidence
		481	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.