Job Description Q62270 Confidence 100.00% Date Tue Jul 30 13:00:53 BST 2013 Rank 6 Aligned Residues 412 % Identity 45% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:57.690 Y:71.766 Z:50.892

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		59	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	F	R	A	L	Y	D	F	T	A	R	C	A	E	E	L	S	V	S	R	G	D	R	L	Y	A	L	K	E	E	G	D	Y	I	F	A	Q	R	L	S	G	P	P	S	T	G	L	V	P	V	T	Y	L	A	K	A	T	P	E	P
Query Conservation
Alig confidence																																										.																	.	.
Template Conservation																																										.																	.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	S	G	E	W	W	K	A	R	S	L	A	.	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	.	.	S
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T										T	T							T	T	.	T								G	G	G				T	T	.	.	S
Template Predicted Secondary structure																																										.																	.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100		.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.			.
		119	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.						.	.	.	.	170	.	.	.
Predicted Secondary structure																																																	.	.	.	.	.
Query SS confidence																																																	.	.	.	.	.
Query Sequence		P	S	D	Q	P	W	Y	F	S	G	I	S	R	A	Q	A	Q	Q	L	L	L	S	P	A	N	A	P	G	A	F	L	I	R	P	S	E	S	S	I	G	G	Y	S	L	S	V	R	.	.	.	.	.	A	Q	A	K	V	C	H	Y
Query Conservation																																																	.	.	.	.	.
Alig confidence																																																	.	.	.	.	.
Template Conservation
Template Sequence		L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y
Template Known Secondary structure		G	G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T											T	T	T
Template Predicted Secondary structure
Template SS confidence
		118	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.
		174	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.				.	.	.	.	.	.	.	230
Predicted Secondary structure																																																			.	.	.
Query SS confidence																																																			.	.	.
Query Sequence		R	I	C	M	A	P	S	G	S	L	Y	L	Q	E	G	Q	L	F	P	S	L	D	A	L	L	A	Y	Y	K	T	N	W	K	L	I	Q	N	P	L	L	Q	P	C	I	P	Q	I	P	L	.	.	.	V	Q	D	E	W	E	R	P
Query Conservation																																																			.	.	.
Alig confidence																																																			.	.	.
Template Conservation
Template Sequence		K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	W	E	K	D	A	W	E	I	P
Template Known Secondary structure				B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B												T	T		S	B
Template Predicted Secondary structure
Template SS confidence
		178	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
Predicted Secondary structure
Query SS confidence
Query Sequence		R	S	E	F	V	L	R	R	K	L	G	E	G	F	F	G	E	V	W	E	G	L	W	L	G	S	I	P	V	A	V	K	V	I	K	S	A	D	M	K	L	A	D	L	T	K	E	I	E	A	L	K	S	L	R	H	E	R	L	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V
Template Known Secondary structure		G	G	G											T	T									T	T	T												S	S														T				T	T	B
Template Predicted Secondary structure
Template SS confidence
		238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.
		291	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Predicted Secondary structure
Query SS confidence
Query Sequence		R	L	H	A	I	C	S	L	G	E	P	V	Y	I	V	T	E	L	M	G	K	G	N	L	Q	V	Y	L	G	S	S	E	G	K	A	L	S	L	P	H	L	L	G	F	A	C	Q	V	A	E	G	M	S	Y	L	E	E	R	R	V
Query Conservation
Alig confidence								.
Template Conservation								.
Template Sequence		K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y
Template Known Secondary structure								.		S	S	S									T	T		B							S	T	T	G	G	G																							T	T
Template Predicted Secondary structure								.
Template SS confidence
		298	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410
Predicted Secondary structure
Query SS confidence
Query Sequence		V	H	R	D	L	A	A	R	N	V	L	V	G	D	D	L	T	C	K	V	A	D	F	G	L	A	R	L	L	K	D	D	V	Y	S	P	S	S	G	S	K	I	P	V	K	W	T	A	P	E	A	A	N	Y	R	V	F	S	Q	K
Query Conservation
Alig confidence																													.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																													.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K
Template Known Secondary structure				S			S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S
Template Predicted Secondary structure																													.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		357	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
		411	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470
Predicted Secondary structure
Query SS confidence
Query Sequence		S	D	V	W	S	F	G	I	L	L	Y	E	V	F	T	Y	G	Q	C	P	Y	E	G	M	T	N	H	E	T	L	Q	Q	I	S	R	G	Y	R	L	P	R	P	A	V	C	P	A	E	V	Y	V	L	M	V	E	C	W	K	G	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R
Template Known Secondary structure																T	T	T			S	S	T	T												T	T							T	T													T		S	S
Template Predicted Secondary structure
Template SS confidence
		417	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.
		471	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	E	E	R	P	T	F	A	I	L	R	E	K	L	N	A	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F
Template Known Secondary structure		G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		477	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.