|   |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | |
. | . | . | . | 260 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | R | P | R | S | E | F | V | L | R | R | K | L | G | E | G | F | F | G | E | V | W | E | G | L | W | L | G | . |
S | I | P | V | A | V | K | V | I | . |
. |
. |
. |
. |
. |
. |
K | S | A | D | M | K | L | A | D | L | T | K | E | I | E |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   | . |   |   |   |
|
|
|
|   |
| . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| Template Sequence |   |
H | L | T | M | N | D | F | S | V | H | R | I | I | G | R | G | G | F | G | E | V | Y | G | C | R | K | A | D | T | G | K | M | Y | A | M | K | C | L | D | K | K | R | I | K | M | K | Q | G | E | T | L | A | L | N | E | R | I | M | L | S |
| Template Known Secondary structure |   |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
|   |
|   |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | L | K | S | L | R | H | E | R | L | I | R | L | H | A | I | C | S | L | G | E | P | V | Y | I | V | T | E | L | M | G | K | G | N | L | Q | V | Y | L | G | S | S | E | G | K | A | L | S | L | P | H | L | L | G | F | A | C | Q | V | A |
| Query Conservation |   |
  |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |   | . | . |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |
| Template Sequence |   |
L | V | S | T | G | D | C | P | F | I | V | C | M | S | Y | A | F | H | T | P | D | K | L | S | F | I | L | D | L | M | N | G | G | D | L | H | Y | H | L | S | Q | H | G | . |
. |
V | F | S | E | A | D | M | R | F | Y | A | A | E | I | I |
| Template Known Secondary structure |   |
 |  | S | S | S |
|
| S | S | B |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  |  |  |
| . | . | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | |
|
. | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
|   |
|   |   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | G | M | S | Y | L | E | E | R | R | V | V | H | R | D | L | A | A | R | N | V | L | V | G | D | D | L | T | C | K | V | A | D | F | G | L | A | R | L | L | K | D | D | V | Y | S | P | S | S | G | S | K | I | P | V | K | W | T | A | P |
| Query Conservation |   |
  |
|
|   |
|
|
|   |   |   |   |
|
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   | . | . | . |
|   |
|
|
| Template Sequence |   |
L | G | L | E | H | M | H | N | R | F | V | V | Y | R | D | L | K | P | A | N | I | L | L | D | E | H | G | H | V | R | I | S | D | L | G | L | A | C | D | F | S | K | K | K | P | H | A | S | V | G | T | H | G | . |
. |
. |
Y | M | A | P |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |
| S | S |
|
|
|
|
|
|
| S |
| T | T | . | . | . | S |
|
|  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
| . | . | . |
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | |
|
|
. | . | . | . |
|   |
|   |   |
400 | . | . | . | . | . | . | |
. | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | |
|
. | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | A | A | N | Y | R | V | . |
F | S | Q | K | S | D | V | W | S | F | G | I | L | L | Y | E | V | F | T | Y | G | Q | C | P | Y | E | G | . |
. |
M | T | N | H | E | T | L | Q | Q | I | S | R | G | Y | R | L | P | R | P | A | V | C | P |
| Query Conservation |   |
|   |
|   |   |   |   | . |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   | . | . |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
| Template Sequence |   |
E | V | L | Q | K | G | V | A | Y | D | S | S | A | D | W | F | S | L | G | C | M | L | F | K | L | L | R | . |
G | H | S | P | F | R | Q | H | K | T | K | D | K | H | E | I | D | R | M | T | L | T | M | A | V | E | L | P | D | S | F | S |
| Template Known Secondary structure |   |
 |  |  | S | S | S |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
| S | S |
| S | S |
| T |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| T | T | S |
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
. | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . |
|   |
|   |   |
457 | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 480 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
| . | . | . | . | . |
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
| Query Sequence |   |
A | E | V | Y | V | L | M | V | E | C | W | K | G | S | P | E | E | R | P | . |
. |
. |
. |
. |
T | F | A | I | L | R | E |
| Query Conservation |   |
  |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
| . | . | . | . | . |
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |
| Template Sequence |   |
P | E | L | R | S | L | L | E | G | L | L | Q | R | D | V | N | R | R | L | G | C | L | G | R | G | A | Q | E | V | K | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
| S | S | S | T | T | S | T | T | T | S | S | S | S |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
419 | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . |
|   |