|   |   |
193 | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | K | R | C | C | C | L | R | E | I | Q | Q | T | E | E | K | Y | T | D | T | L | G | S | I | Q | Q | H | F | M | K | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
Q | R | F | L | K | P | Q | D | M | E | T | I | F | V | N | I | E | E | L |
| Query Conservation |   |
  |
|
|   |   |
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
| Template Sequence |   |
S | R | A | L | V | I | A | Q | E | L | L | S | S | E | K | A | Y | V | E | X | L | Q | H | L | N | L | D | F | H | G | A | V | X | R | A | L | D | D | X | D | H | E | D | T | L | A | R | E | E | L | R | Q | G | L | S | E | L | P | A | I |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
891 | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 |
|   |
|   |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
F | S | V | H | T | H | F | L | K | E | L | K | D | A | L | A | G | P | G | A | T | T | . |
L | Y | Q | V | F | I | K | Y | K | E | R | F | L | V | Y | G | R | Y | C | S | Q | V | E | S | A | S | K | H | L | D | Q | V | A | T | A | R | E |
| Query Conservation |   |
  |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   | . |
|
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
| Template Sequence |   |
H | D | L | H | Q | G | I | L | E | E | L | E | E | R | L | S | N | W | E | S | Q | Q | K | V | A | D | V | F | L | A | R | E | Q | G | F | D | H | H | A | T | H | I | L | Q | F | D | R | Y | L | G | L | L | S | E | N | C | L | H | S | P |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|
|
|
| T |  |  |  |  | T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
953 | . | . | . | . | . | . | 960 | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . |
|   |
|   |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | |
. | 350 | . | . | . | . | . | . | . | . | . | 360 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | V | Q | M | K | L | E | E | C | S | Q | R | A | N | N | G | R | F | T | L | R | D | L | L | M | V | P | M | Q | R | V | L | K | Y | H | L | L | L | Q | E | L | V | K | H | T | Q | . |
D | A | T | E | K | E | N | L | R | L | A | L | D |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|
|
|   |
|
|   |
|
|
|   |   |
|   |
|   |
|   | . |   |   |   |
|   |   |   |
|   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |
|   |
|
|   |   |
|
|   |
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
| Template Sequence |   |
R | L | A | A | A | V | R | E | F | E | . |
. |
. |
. |
. |
. |
Q | S | T | A | K | H | R | L | L | R | V | V | Q | R | L | F | Q | Y | Q | V | L | L | T | D | Y | L | N | N | L | C | P | D | S | A | E | Y | D | N | T | Q | G | A | L | S |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1013 | . | . | . | . | . | . | 1020 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . |
|   |
|   |   |
362 | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | M | R | D | L | A | Q | C | V | N | E | V | K | R | D | N | E | T | L | R | Q | I | T | N | F | Q | L | S | I | E | N | L | D | Q | S | L | A | N | Y | G | R | P | K | I | D | G | E | L | K | I | T | S | V | E | R | R | S | K | T | D |
| Query Conservation |   |
  |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
| Template Sequence |   |
L | I | S | K | V | T | D | R | A | N | D | S | X | E | Q | G | E | N | L | Q | K | L | V | H | I | E | H | S | V | R | G | Q | G | D | L | L | Q | P | G | R | E | F | L | K | E | G | T | L | X | K | V | T | . |
. |
G | K | N | R | R | P |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
| T | T |
|
|  |  |  |
|
|  |  |  |  |  |  | . | . | T | T |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1073 | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | |
|
. | . | . | . | . | 1130 |
|   |
|   |   |
422 | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | |
. | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | Y | A | F | L | L | D | K | A | L | L | I | C | K | R | R | G | D | S | . |
Y | D | L | K | A | S | V | N | L | H | S | F | Q | V | R | D | D | S | S | G | E | R | D | N | K | K | W | S | H | M | F | L | L | I | E | D | Q | G | A | Q |
| Query Conservation |   |
|   |   |
|
|
|   |   |   |
|
|   |   |
|   |   |   |   |   | . |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
| Template Conservation |   |
  |   |   |   |
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   | . | . |   |
| Template Sequence |   |
R | H | L | F | L | X | N | D | V | L | L | Y | T | Y | P | Q | K | D | G | K | Y | R | L | K | N | T | L | A | V | S | R | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | X | E | K | V | P | Y | A | L | K | I | E | T | S | E | . |
. |
S |
| Template Known Secondary structure |   |
 |  |  |  |  |  | S | S |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
| T | T | S |
| S |  |  |  |  |  |
| S | S | . | . |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . | . |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1131 | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | |
|
. |
|   |
|   |   |
481 | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | Y | E | L | F | F | K | T | R | E | L | K | K | K | W | M | E | Q | F | E | M | A |
| Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|
| Template Sequence |   |
C | L | X | L | S | A | S | S | C | A | E | R | D | E | W | Y | G | C | L | S | R | A |
| Template Known Secondary structure |   |
 |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1184 | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . |
|   |