Job Description P27870 Confidence 100.00% Date Tue Jul 30 13:02:10 BST 2013 Rank 1 Aligned Residues 540 % Identity 95% Template c3ky9B_ PDB info PDB header:apoptosis Chain: B: PDB Molecule:proto-oncogene vav; PDBTitle: autoinhibited vav1 Resolution 2.73 Å Model Dimensions (Å) X:73.769 Y:83.896 Z:59.702

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	W	R	Q	C	T	H	W	L	I	Q	C	R	V	L	P	P	S	H	R	V	T	W	E	G	A	Q	V	C	E	L	A	Q	A	L	R	D	G	V	L	L	C	Q	L	L	N	N	L	L	P	Q	A	I	N	L	R	E	V	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	L	W	R	Q	C	T	H	W	L	I	Q	C	R	V	L	P	P	S	H	R	V	T	W	E	G	A	Q	V	C	E	L	A	Q	A	L	R	D	G	V	L	L	C	Q	L	L	N	N	L	L	P	H	A	I	N	L	R	E	V	N
Template Known Secondary structure														T	T		S		T	T	S	T	T	T	S	T	T											S	S	T											S	T	T	S	S		G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.
		62	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	P	Q	M	S	Q	F	L	C	L	K	N	I	R	T	F	L	S	T	C	C	E	K	F	G	L	K	R	S	E	L	F	E	A	F	D	L	F	D	V	Q	D	F	G	K	V	I	Y	T	L	S	A	L	S	W	T	P	I	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	R	P	Q	M	S	Q	F	L	C	L	K	N	I	R	T	F	L	S	T	C	C	E	K	F	G	L	K	R	S	E	L	F	E	A	F	D	L	F	D	V	Q	D	F	G	K	V	I	Y	T	L	S	A	L	S	W	T	P	I	A
Template Known Secondary structure		S	S		T	T	B																		T	T				T	T	S	S								T		S															S	T	T	T
Template Predicted Secondary structure
Template SS confidence
		62	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	N	K	G	I	M	P	F	P	T	E	D	S	A	L	N	D	E	D	I	Y	S	G	L	S	D	Q	I	D	D	T	A	E	E	D	E	D	L	Y	D	C	V	E	N	E	E	A	E	G	D	E	I	Y	E	D	L	M	R	L	E
Query Conservation
Alig confidence											.	.	.	.	.	.	.	.														.	.	.	.	.																								.	.
Template Conservation											.	.	.	.	.	.	.	.														.	.	.	.	.																								.	.
Template Sequence		Q	N	R	G	I	M	P	F	D	.	.	.	.	.	.	.	.	E	D	I	Y	S	G	L	S	D	Q	I	D	D	.	.	.	.	.	E	D	L	Y	D	C	V	E	N	E	E	A	E	G	D	E	I	Y	E	D	L	M	R	.	.
Template Known Secondary structure		G	G	G	T						.	.	.	.	.	.	.	.			G	G	G	G								.	.	.	.	.	T	T	G	G	G	G	S			T	T													.	.
Template Predicted Secondary structure											.	.	.	.	.	.	.	.														.	.	.	.	.																								.	.
Template SS confidence
		122	.	.	.	.	.	.	.	130									.	.	.	.	.	.	.	.	.	140	.	.	.						.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	V	P	T	P	P	K	M	T	E	Y	D	K	R	C	C	C	L	R	E	I	Q	Q	T	E	E	K	Y	T	D	T	L	G	S	I	Q	Q	H	F	M	K	P	L	Q	R	F	L	K	P	Q	D	M	E	T	I	F	V	N	I	E
Query Conservation
Alig confidence		.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	S	M	T	E	Y	D	K	R	C	C	C	L	R	E	I	Q	Q	T	E	E	K	Y	T	D	T	L	G	S	I	Q	Q	H	F	L	K	P	L	Q	R	F	L	K	P	Q	D	I	E	I	I	F	I	N	I	E
Template Known Secondary structure		.	.	.	.	.	.				T	T																												T						T	T	S		T	T	T	S
Template Predicted Secondary structure		.	.	.	.	.	.
Template SS confidence
								180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	F	S	V	H	T	H	F	L	K	E	L	K	D	A	L	A	G	P	G	A	T	T	L	Y	Q	V	F	I	K	Y	K	E	R	F	L	V	Y	G	R	Y	C	S	Q	V	E	S	A	S	K	H	L	D	Q	V	A	T	A	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	L	L	R	V	H	T	H	F	L	K	E	M	K	E	A	L	G	T	P	G	A	A	N	L	Y	Q	V	F	I	K	Y	K	E	R	F	L	V	Y	G	R	Y	C	S	Q	V	E	S	A	S	K	H	L	D	R	V	A	A	A	R
Template Known Secondary structure																				S	S	T	T		S								T	T	G	G	G	G																						T
Template Predicted Secondary structure
Template SS confidence
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.
		302	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	D	V	Q	M	K	L	E	E	C	S	Q	R	A	N	N	G	R	F	T	L	R	D	L	L	M	V	P	M	Q	R	V	L	K	Y	H	L	L	L	Q	E	L	V	K	H	T	Q	D	A	T	E	K	E	N	L	R	L	A	L	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	D	V	Q	M	K	L	E	E	C	S	Q	R	A	N	N	G	R	F	T	L	R	D	L	L	M	V	P	M	Q	R	V	L	K	Y	H	L	L	L	Q	E	L	V	K	H	T	Q	E	A	M	E	K	E	N	L	R	L	A	L	D
Template Known Secondary structure						T	T	T	T								T	T	S																											T
Template Predicted Secondary structure
Template SS confidence
		302	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	M	R	D	L	A	Q	C	V	N	E	V	K	R	D	N	E	T	L	R	Q	I	T	N	F	Q	L	S	I	E	N	L	D	Q	S	L	A	N	Y	G	R	P	K	I	D	G	E	L	K	I	T	S	V	E	R	R	S	K	T	D
Query Conservation
Alig confidence																																																					.	.	.
Template Conservation																																																					.	.	.
Template Sequence		A	M	R	D	L	A	Q	C	V	N	E	V	K	R	D	N	E	T	L	R	Q	I	T	N	F	Q	L	S	I	E	N	L	D	Q	S	L	A	H	Y	G	R	P	K	I	D	G	E	L	K	I	T	.	.	.	S	V	E	R	M	D
Template Known Secondary structure																																T			S		G	G	G	G													.	.	.		S
Template Predicted Secondary structure																																																					.	.	.
Template SS confidence
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.				.	.	.	.	.	.
		422	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Y	A	F	L	L	D	K	A	L	L	I	C	K	R	R	G	D	S	Y	D	L	K	A	S	V	N	L	H	S	F	Q	V	R	D	D	S	S	G	E	R	D	N	K	K	W	S	H	M	F	L	L	I	E	D	Q	G	A	Q	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	Y	A	F	L	L	D	K	A	L	L	I	C	K	R	R	G	D	S	Y	D	L	K	D	F	V	N	L	H	S	F	Q	V	R	D	D	S	S	G	D	R	D	N	K	K	W	S	H	M	F	L	L	I	E	D	Q	G	A	Q	G
Template Known Secondary structure								T	T									T	T										G	G	G								S	S	T	T	T	T		T	T									T	T	S	S
Template Predicted Secondary structure
Template SS confidence
		422	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.
		482	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	E	L	F	F	K	T	R	E	L	K	K	K	W	M	E	Q	F	E	M	A	I	S	N	I	Y	P	E	N	A	T	A	N	G	H	D	F	Q	M	F	S	F	E	E	T	T	S	C	K	A	C	Q	M	L	L	R	G	T	F	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	E	L	F	F	K	T	R	E	L	K	K	K	W	M	E	Q	F	E	M	A	I	S	N	I	Y	P	E	N	A	T	A	N	G	H	D	F	Q	M	F	S	F	E	E	T	T	S	C	K	A	C	Q	M	L	L	R	G	T	F	Y
Template Known Secondary structure							S	S																			S		T	T	T	T	G	G	G									S	S			B		T	T	T		S	B			S	S	S
Template Predicted Secondary structure
Template SS confidence
		482	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.
		542	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	G	Y	R	C	Y	R	C	R	A	P	A	H	K	E	C	L	G	R	V	P	P	C	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	G	Y	R	C	H	R	C	R	A	S	A	H	K	E	C	L	G	R	V	P	P	C	G
Template Known Secondary structure							T	T	T						S	G	G	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		542	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.