Job Description P27870 Confidence 100.00% Date Tue Jul 30 13:02:10 BST 2013 Rank 3 Aligned Residues 372 % Identity 93% Template c3bjiA_ PDB info PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1 Resolution 2.60 Å Model Dimensions (Å) X:72.158 Y:77.478 Z:45.939

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		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	T	E	Y	D	K	R	C	C	C	L	R	E	I	Q	Q	T	E	E	K	Y	T	D	T	L	G	S	I	Q	Q	H	F	M	K	P	L	Q	R	F	L	K	P	Q	D	M	E	T	I	F	V	N	I	E	E	L	F	S	V	H	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	T	E	Y	D	K	R	C	C	C	L	R	E	I	Q	Q	T	E	E	K	Y	T	D	T	L	G	S	I	Q	Q	H	F	L	K	P	L	Q	R	F	L	K	P	Q	D	I	E	I	I	F	I	N	I	E	D	L	L	R	V	H	T
Template Known Secondary structure																																T	T					T	T	T	S										T	T
Template Predicted Secondary structure
Template SS confidence
		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	F	L	K	E	L	K	D	A	L	A	G	P	G	A	T	T	L	Y	Q	V	F	I	K	Y	K	E	R	F	L	V	Y	G	R	Y	C	S	Q	V	E	S	A	S	K	H	L	D	Q	V	A	T	A	R	E	D	V	Q	M	K	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	F	L	K	E	M	K	E	A	L	G	T	P	G	A	A	N	L	Y	Q	V	F	I	K	Y	K	E	R	F	L	V	Y	G	R	Y	C	S	Q	V	E	S	A	S	K	H	L	D	R	V	A	A	A	R	E	D	V	Q	M	K	L
Template Known Secondary structure													T	T	T	S	T	T	S								T	T	G	G	G
Template Predicted Secondary structure
Template SS confidence
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.
		309	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	E	C	S	Q	R	A	N	N	G	R	F	T	L	R	D	L	L	M	V	P	M	Q	R	V	L	K	Y	H	L	L	L	Q	E	L	V	K	H	T	Q	D	A	T	E	K	E	N	L	R	L	A	L	D	A	M	R	D	L	A	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	E	C	S	Q	R	A	N	N	G	R	F	T	L	R	D	L	L	M	V	P	M	Q	R	V	L	K	Y	H	L	L	L	Q	E	L	V	K	H	T	Q	E	A	M	E	K	E	N	L	R	L	A	L	D	A	M	R	D	L	A	Q
Template Known Secondary structure										T	T	S	S							T							T	T										T	T				S
Template Predicted Secondary structure
Template SS confidence
		309	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	V	N	E	V	K	R	D	N	E	T	L	R	Q	I	T	N	F	Q	L	S	I	E	N	L	D	Q	S	L	A	N	Y	G	R	P	K	I	D	G	E	L	K	I	T	S	V	E	R	R	S	K	T	D	R	Y	A	F	L	L	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	V	N	E	V	K	R	D	N	E	T	L	R	Q	I	T	N	F	Q	L	S	I	E	N	L	D	Q	S	L	A	H	Y	G	R	P	K	I	D	G	E	L	K	I	T	S	V	E	R	R	S	K	M	D	R	Y	A	F	L	L	D
Template Known Secondary structure																						S			S			S		G	G	G	G														S	S			S										S
Template Predicted Secondary structure
Template SS confidence
		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.
		429	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	A	L	L	I	C	K	R	R	G	D	S	Y	D	L	K	A	S	V	N	L	H	S	F	Q	V	R	D	D	S	S	G	E	R	D	N	K	K	W	S	H	M	F	L	L	I	E	D	Q	G	A	Q	G	Y	E	L	F	F	K	T
Query Conservation
Alig confidence																																			.	.	.	.	.
Template Conservation																																			.	.	.	.	.
Template Sequence		K	A	L	L	I	C	K	R	R	G	D	S	Y	D	L	K	D	F	V	N	L	H	S	F	Q	V	R	D	D	D	N	K	K	.	.	.	.	.	W	S	H	M	F	L	L	I	E	D	Q	G	A	Q	G	Y	E	L	F	F	K	T
Template Known Secondary structure		S									S	S										G	G	G									S	T	.	.	.	.	.	T									S	S	S	S								S	S
Template Predicted Secondary structure																																			.	.	.	.	.
Template SS confidence
		429	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.						.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.
		489	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	E	L	K	K	K	W	M	E	Q	F	E	M	A	I	S	N	I	Y	P	E	N	A	T	A	N	G	H	D	F	Q	M	F	S	F	E	E	T	T	S	C	K	A	C	Q	M	L	L	R	G	T	F	Y	Q	G	Y	R	C	Y	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	E	L	K	K	K	W	M	E	Q	F	E	M	A	I	S	N	I	Y	P	E	N	A	T	A	N	G	H	D	F	Q	M	F	S	F	E	E	T	T	S	C	K	A	C	Q	M	L	L	R	G	T	F	Y	Q	G	Y	R	C	H	R
Template Known Secondary structure																				S		T	T	T	T	G	G	G										S			B		T	T	T		S	B			S	S	S							T	T
Template Predicted Secondary structure
Template SS confidence
		489	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.
		549	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	R	A	P	A	H	K	E	C	L	G	R	V	P	P	C	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	R	A	S	A	H	K	E	C	L	G	R	V	P	P	C	G
Template Known Secondary structure		T						G	G	G	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		549	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D