Return to main results Retrieve Phyre Job Id

Job DescriptionP27870
Confidence100.00%DateTue Jul 30 13:02:10 BST 2013
Rank5Aligned Residues350
% Identity23%Templatec2dx1A_
PDB info PDB header:signaling proteinChain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef
Resolution2.36 Å
Model Dimensions (Å)X:60.979 Y:79.757 Z:51.875

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   139140.........150.........160.........170... ......180.........190
Predicted Secondary structure 



















........








Query SS confidence 


































. . . . . . . .
















Query Sequence  EDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEI. . . . . . . . YEDLMRLESVPTPPKMT
Query Conservation        
                            ........                 
Alig confidence 


































........
















Template Conservation   
         


 
  
  
 
       

 
      



  

           
Template Sequence  EALWDHVTXDDQELGFKAGDVIEVXDATNREWWWGRVADGEGWFPASFVRLRVNQDAQSS
Template Known Secondary structure  SS
B



TTB

B
TT


SSS
SS
GGG
S




Template Predicted Secondary structure 








































Template SS confidence 



























































   129130.........140.........150.........160.........170.........180........
 
   191........200.........210.........220...... ...230.........240.......
Predicted Secondary structure  ...



Query SS confidence 



































. . .




















Query Sequence  EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQR. . . FLKPQDMETIFVNIEELFSVH
Query Conservation     

  

 


 

  

  
  
       
  ... 
       

 

  
    
Alig confidence 



































...




















Template Conservation   
  
  

 


 

  

  
  
   
  

      

      

 

  
   
Template Sequence  KDQXRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADXFSEEQLRTIFGNIEDIYRCQ
Template Known Secondary structure  TTT
TTT

TT
Template Predicted Secondary structure 








Template SS confidence 



























































   210.........220.........230.........240.........250.........260.........
 
   248.250.........260..... ....270.........280.........290.........300.....
Predicted Secondary structure 




..



Query SS confidence 

















. .







































Query Sequence  THFLKELKDALAGPGATT. . LYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQ
Query Conservation    

  
           ..

  
      
  
  
  
   
   
           
Alig confidence 

















..
































.





Template Conservation    

  

            

  
         
  
      
   
    .      
Template Sequence  KAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLT. KLSKYV
Template Known Secondary structure  TT

SSSGGG


TT.T
Template Predicted Secondary structure 









.
Template SS confidence 



























































   270.........280.........290.........300.........310.........320.. ......
 
   306...310.........320.........330.........340........ .350.........360....
Predicted Secondary structure 










.

Query SS confidence 










































.















Query Sequence  MKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQ. DATEKENLRLALDAMR
Query Conservation                  
   
  




 

 


  
 
 
 .   
   
  
     
Alig confidence 










































.















Template Conservation                
 
   
  




 

 


 



 
   
 
   
  

    
Template Sequence  YFFEACRLLQKXIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAXK
Template Known Secondary structure  T

S

TS
TT
TT
Template Predicted Secondary structure 












Template SS confidence 



























































   329330.........340.........350.........360.........370.........380........
 
   365....370.........380.........390...... ...400.........410.........420..
Predicted Secondary structure 





..











Query SS confidence 































. .

























Query Sequence  DLAQCVNEVKRDNETLRQITNFQLSIENLDQS. . LANYGRPKIDGELKITSVERRSKTDR
Query Conservation   
   


     
       
   
      ..
   
 
   
   
          
Alig confidence 































..

























Template Conservation   
   


  
  
    
  
   
       
      

  
               
Template Sequence  NVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQR
Template Known Secondary structure  SBS

SS




SSSS
Template Predicted Secondary structure 


















Template SS confidence 



























































   389390.........400.........410.........420.........430.........440........
 
   423......430..... ....440.........450.........460.........470.........
Predicted Secondary structure 

...






























Query SS confidence 












. . .











































Query Sequence  YAFLLDKALLICK. . . RRGDSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGA
Query Conservation    


   

  
...        
    
    
                         
Alig confidence 












...



















.................






Template Conservation    


 
 

  
    
      
  
        .................  
   
Template Sequence  XFFLFDHQLIYCKKDLLRRDVLYYKGRLDXDGLEVV. . . . . . . . . . . . . . . . . IKNAFRL
Template Known Secondary structure  TT
TT
TT
TTT

.................

Template Predicted Secondary structure 













.................

Template SS confidence 



























































   449450.........460.........470.........480.... .....490.
 
   480.........490.........500......
Predicted Secondary structure 


Query SS confidence 


























Query Sequence  QGYELFFKTRELKKKWMEQFEMAISNI
Query Conservation      
       
  
   
  
    
Alig confidence 


























Template Conservation      
   
  

  
   
       
Template Sequence  HSHLLCTRKPEQKQRWLKAFAREREQV
Template Known Secondary structure 


S
Template Predicted Secondary structure 

Template SS confidence 


























   505....510.........520.........530.
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D