Job Description P27870 Confidence 100.00% Date Tue Jul 30 13:02:10 BST 2013 Rank 9 Aligned Residues 310 % Identity 23% Template c1x86A_ PDB info PDB header:signaling protein/membrane protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12; PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa Resolution 3.22 Å Model Dimensions (Å) X:72.527 Y:76.225 Z:42.624

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		194	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.			.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.
Predicted Secondary structure																																			.	.
Query SS confidence																																			.	.
Query Sequence		K	R	C	C	C	L	R	E	I	Q	Q	T	E	E	K	Y	T	D	T	L	G	S	I	Q	Q	H	F	M	K	P	L	Q	R	.	.	F	L	K	P	Q	D	M	E	T	I	F	V	N	I	E	E	L	F	S	V	H	T	H	F	L
Query Conservation																																			.	.
Alig confidence																																			.	.
Template Conservation
Template Sequence		K	R	Q	E	V	I	N	E	L	F	Y	T	E	R	A	H	V	R	T	L	K	V	L	D	Q	V	F	Y	Q	R	V	S	R	E	G	I	L	S	P	S	E	L	R	K	I	F	S	N	L	E	D	I	L	Q	L	H	I	G	L	N
Template Known Secondary structure																												T								S		S										T	T
Template Predicted Secondary structure
Template SS confidence
		787	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.
		252	.	.	.	.	.	.	.	260	.	.	.				.	.	.	.	.	.	270	.	.	.	.							.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.
Predicted Secondary structure														.	.	.												.	.	.	.	.	.
Query SS confidence														.	.	.												.	.	.	.	.	.
Query Sequence		K	E	L	K	D	A	L	A	G	P	G	A	.	.	.	T	T	L	Y	Q	V	F	I	K	Y	K	.	.	.	.	.	.	E	R	F	L	V	Y	G	R	Y	C	S	Q	V	E	S	A	S	K	H	L	D	Q	V	A	T	A	R	E
Query Conservation														.	.	.												.	.	.	.	.	.
Alig confidence														.	.	.												.	.	.	.	.	.
Template Conservation
Template Sequence		E	Q	M	K	A	V	R	K	R	N	E	T	S	V	I	D	Q	I	G	E	D	L	L	T	W	F	S	G	P	G	E	E	K	L	K	H	A	A	A	T	F	C	S	N	Q	P	F	A	L	E	M	I	K	S	R	Q	K	K	D	S
Template Known Secondary structure												S	S	S	S													S																	T
Template Predicted Secondary structure
Template SS confidence
		847	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.
		303	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	V	Q	M	K	L	E	E	C	S	Q	R	A	N	N	G	R	F	T	L	R	D	L	L	M	V	P	M	Q	R	V	L	K	Y	H	L	L	L	Q	E	L	V	K	H	T	Q	D	A	T	E	K	E	N	L	R	L	A	L	D	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	F	Q	T	F	V	Q	D	A	E	S	N	P	L	C	R	R	L	Q	L	K	D	I	I	P	T	Q	M	Q	R	L	T	K	Y	P	L	L	L	D	N	I	A	K	Y	T	E	W	P	T	E	R	E	K	V	K	K	A	A	D	H
Template Known Secondary structure												T	S	G	G	G	T	T							T	T																			T
Template Predicted Secondary structure
Template SS confidence
		907	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.
		363	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.														400	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																							.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																							.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		M	R	D	L	A	Q	C	V	N	E	V	K	R	D	N	E	T	L	R	Q	I	T	N	F	Q	L	S	I	E	N	L	D	Q	S	L	A	N	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	G	R	P	K	I	D	G	E	L
Query Conservation																																							.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																							.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		C	R	Q	I	L	N	F	V	N	Q	A	V	K	E	A	E	N	K	Q	R	L	E	D	Y	Q	R	R	L	D	T	S	S	L	K	L	S	E	Y	P	N	V	E	E	L	R	N	L	D	L	T	K	R	K	M	I	H	E	G	P	L
Template Known Secondary structure																												T				S	S			S	S	S		G	G	G					S			G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		967	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.
		410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440							.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.
Predicted Secondary structure																																	.	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.	.
Query Sequence		K	I	T	S	V	E	R	R	S	K	T	D	R	Y	A	F	L	L	D	K	A	L	L	I	C	K	R	R	G	D	S	.	.	.	.	.	.	Y	D	L	K	A	S	V	N	L	H	S	F	Q	V	R	D	D	S	S	G	E	R	D
Query Conservation																																	.	.	.	.	.	.
Alig confidence									.																								.	.	.	.	.	.																						.	.
Template Conservation									.																																																			.	.
Template Sequence		V	W	K	V	N	R	D	.	K	T	I	D	L	Y	T	L	L	L	E	D	I	L	V	L	L	Q	K	Q	D	D	R	L	V	L	R	C	H	S	T	F	S	P	V	I	K	L	S	T	V	L	V	R	Q	V	A	T	D	N	.	.
Template Known Secondary structure					S		T	T	.											S	S							B		S	S												S				T	T	S							S	S	S	T	.	.
Template Predicted Secondary structure									.																																																			.	.
Template SS confidence
		1027	.	.	1030	.	.	.		.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.
		464	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	K	K	W	S	H	M	F	L	L	I	E	D	Q	G	A	Q	G	Y	E	L	F	F	K	T	R	E	L	K	K	K	W	M	E	Q	F	E	M	A	I	S	N	I	Y	P	E
Query Conservation
Alig confidence		.	.	.
Template Conservation		.	.	.
Template Sequence		.	.	.	K	A	L	F	V	I	S	M	S	D	N	G	A	Q	I	Y	E	L	V	A	Q	T	V	S	E	K	T	V	W	Q	D	L	I	C	R	M	A	A	S	V	K	E	Q
Template Known Secondary structure		.	.	.	T							B		S	S		B								S	S																				T
Template Predicted Secondary structure		.	.	.
Template SS confidence
					1095	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D