Job Description Q64434 Confidence 100.00% Date Wed Jul 10 14:13:37 BST 2013 Rank 8 Aligned Residues 368 % Identity 35% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:89.250 Y:61.134 Z:49.855

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		74	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	S	E	P	W	F	F	G	C	I	S	R	S	E	A	M	H	R	L	Q	A	E	D	N	S	K	G	A	F	L	I	R	V	S	Q	K	P	G	A	D	Y	V	L	S	V	R	D	A	Q	A	V	R	H	Y	R	I	W	K	N	N
Query Conservation
Alig confidence																																					.
Template Conservation																																					.
Template Sequence		E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	.	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K
Template Known Secondary structure		G	G	S	T	T	B			S												S	S	S			T	T									.	T	T	T									T	T											T
Template Predicted Secondary structure																																					.
Template SS confidence
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.		.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
		134	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.												.	180	.	.
Predicted Secondary structure																																															.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																															.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	G	R	L	H	L	N	E	A	V	S	F	S	N	L	S	E	L	V	D	Y	H	K	T	Q	S	L	S	H	G	L	Q	L	S	M	P	C	W	K	H	K	T	E	P	L	.	.	.	.	.	.	.	.	.	.	.	P	H	W	D
Query Conservation																																															.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																															.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A	L	P	M	D	T	E	V	Y	E	S	P	Y	A	D
Template Known Secondary structure		T	S				S	T	T				B	S	S									T	T	B		T	T	S	S	S				S	B				S				T	T			G	G	G	S	G	G	G	S		G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		223	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.
		183	.	.	.	.	.	.	190	.	.	.	.	.	.									.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.				.	.	.	.	.	.	220	.	.	.	.	.			.	.	.	.
Predicted Secondary structure																.	.	.	.	.	.	.	.																		.	.	.													.	.
Query SS confidence																.	.	.	.	.	.	.	.																		.	.	.													.	.
Query Sequence		D	W	E	R	P	R	E	E	F	T	L	C	K	K	.	.	.	.	.	.	.	.	L	G	A	G	Y	F	G	E	V	F	E	A	L	W	K	G	Q	.	.	.	V	H	V	A	V	K	V	I	S	R	D	N	.	.	L	L	H	Q
Query Conservation																.	.	.	.	.	.	.	.																		.	.	.													.	.
Alig confidence																.	.	.	.	.	.	.	.																		.	.	.													.	.
Template Conservation
Template Sequence		P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K
Template Known Secondary structure		T	T	S				S	S	S	B			G	G	G												T	T											T	T												S	G	G	G		G	G	G
Template Predicted Secondary structure
Template SS confidence
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.
		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	T	F	Q	A	E	I	Q	A	M	K	K	L	R	H	K	H	I	L	S	L	Y	A	V	A	T	A	G	D	P	V	Y	I	I	T	E	L	M	P	K	G	N	L	L	Q	L	L	R	D	S	D	E	K	A	L	P	I	L	E	L
Query Conservation
Alig confidence																											.																									.	.
Template Conservation																											.																									.	.
Template Sequence		D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	.	.	R	H	V	K	D	K	N	I
Template Known Secondary structure																	T	T	B								.		S	S	S									T	T		B									.	.	T	T	S
Template Predicted Secondary structure																											.																									.	.
Template SS confidence
		415	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.			.	.	.	.	.	.	470	.
		290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340				.	.	.	.	.	.
Predicted Secondary structure																																																					.	.	.
Query SS confidence																																																					.	.	.
Query Sequence		V	D	F	A	S	Q	V	A	E	G	M	C	Y	L	E	S	Q	N	Y	I	H	R	D	L	A	A	R	N	V	L	V	T	E	N	N	L	C	K	V	G	D	F	G	L	A	R	L	V	K	E	D	.	.	.	I	Y	L	S	H	E
Query Conservation																																																					.	.	.
Alig confidence																																																					.	.	.
Template Conservation
Template Sequence		I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H
Template Known Secondary structure																		T	T				S			S	G	G	G						T	T							T	T					T	T								S		B	T
Template Predicted Secondary structure
Template SS confidence
		472	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.
		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	N	V	P	Y	K	W	T	A	P	E	A	L	S	R	G	H	Y	S	I	K	S	D	V	W	S	F	G	V	L	L	H	E	I	F	S	R	G	Q	M	P	Y	P	G	M	S	N	H	E	T	F	L	R	V	D	A	G	Y	R	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M
Template Known Secondary structure		T	B		G	G	G	G																													T	T	T			S	S	T	T												T	T
Template Predicted Secondary structure
Template SS confidence
		532	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.
		407	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	C	P	L	E	C	P	P	N	I	H	K	L	M	L	S	C	W	S	R	D	P	K	Q	R	P	C	F	K	D	L	C	E	K	L	T	G	I	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y	Y
Template Known Secondary structure					T	T													T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		592	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D