|   |   |
181 | . | . | . | . | . | . | . | . | 190 | . | . | . | . | |
|
. | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
|
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
. | 230 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| Query Sequence |   |
W | D | D | W | E | R | P | R | E | E | F | T | L | C | . |
. |
K | K | L | G | A | G | Y | F | G | E | V | F | E | A | L | W | K | G | Q | V | . |
. |
. |
. |
H | V | A | V | K | V | I | S | R | D | N | L | L | H | . |
Q | H | T | F | Q |
| Query Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |   |   |   | . | . |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . |   |
|
|
|
|   |
|   |   |   |   |   |   |   | . |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
V | K | D | V | L | I | P | H | E | R | V | V | T | H | S | D | R | V | I | G | K | G | H | F | G | V | V | Y | H | G | E | Y | I | D | Q | A | Q | N | R | I | Q | C | A | I | K | S | L | S | R | I | T | E | M | Q | Q | V | E | A | F | L |
| Template Known Secondary structure |   |
T | G | G | G | B |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | |
. | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | E | I | Q | A | M | K | K | L | R | H | K | H | I | L | S | L | Y | A | V | A | T | . |
A | G | D | P | V | Y | I | I | T | E | L | M | P | K | G | N | L | L | Q | L | L | R | D | S | D | E | K | A | L | P | I | L | E | L | V | D | F |
| Query Conservation |   |
  |
|   |   |
|
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   | . |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
R | E | G | L | L | M | R | G | L | N | H | P | N | V | L | A | L | I | G | I | M | L | P | P | E | G | L | P | H | V | L | L | P | Y | M | C | H | G | D | L | L | Q | F | I | R | S | P | Q | R | N | . |
P | T | V | K | D | L | I | S | F |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  | T |
|
|
| T | T | B |
|
|
|
|  |  |  |
|
| S | S | S |
|
|  |  |  |  |
|
|
| T | T |
| B |  |  |  |  |  |  |
| T | T |
|
| . |
| B |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | |
1180 | . | . | . | . | . | . | . | . |
|   |
|   |   |
293 | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | |
|
|
|
. |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
| Query Sequence |   |
A | S | Q | V | A | E | G | M | C | Y | L | E | S | Q | N | Y | I | H | R | D | L | A | A | R | N | V | L | V | T | E | N | N | L | C | K | V | G | D | F | G | L | A | R | L | V | K | E | D | I | Y | L | S | H | E | H | . |
. |
. |
. |
N |
| Query Conservation |   |
  |   |   |
|
|   |
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
| Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
G | L | Q | V | A | R | G | M | E | Y | L | A | E | Q | K | F | V | H | R | D | L | A | A | R | N | C | M | L | D | E | S | F | T | V | K | V | A | D | F | G | L | A | R | D | I | L | D | R | E | Y | Y | S | V | Q | Q | H | R | H | A | R |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
| T | T | S | S |
| T | T | T | T | G | G | G | G |
| S |
|
| S | S |
| T | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1189 | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . |
|   |
|   |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | P | Y | K | W | T | A | P | E | A | L | S | R | G | H | Y | S | I | K | S | D | V | W | S | F | G | V | L | L | H | E | I | F | S | R | G | Q | M | P | Y | P | G | M | S | N | H | E | T | F | L | R | V | D | A | G | Y | R | M | P | C |
| Query Conservation |   |
  |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | P | V | K | W | T | A | L | E | S | L | Q | T | Y | R | F | T | T | K | S | D | V | W | S | F | G | V | L | L | W | E | L | L | T | R | G | A | P | P | Y | R | H | I | D | P | F | D | L | T | H | F | L | A | Q | G | R | R | L | P | Q |
| Template Known Secondary structure |   |
| G | G | G | G | S |
|  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
| T | T | T | T | S |
| G | G | G |  |  |  |  |  |  | T | T |
|
|
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1249 | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . |
|   |
|   |   |
409 | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | L | E | C | P | P | N | I | H | K | L | M | L | S | C | W | S | R | D | P | K | Q | R | P | C | F | K | D | L | C | E | K | L | T | G | I | T | R |
| Query Conservation |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |   |
|
|   |   |
|   |   |
|   |   |
| Template Sequence |   |
P | E | Y | C | P | D | S | L | Y | Q | V | M | Q | Q | C | W | E | A | D | P | A | V | R | P | T | F | R | V | L | V | G | E | V | E | Q | I | V | S |
| Template Known Secondary structure |   |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1309 | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . | . | . | . | 1330 | . | . | . | . | . | . | . | . | . | 1340 | . | . | . | . | . | . |
|   |