Job Description Q64434 Confidence 100.00% Date Wed Jul 10 14:13:37 BST 2013 Rank 71 Aligned Residues 256 % Identity 34% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.						.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure																																.	.	.	.	.
Query SS confidence																																.	.	.	.	.
Query Sequence		D	D	W	E	R	P	R	E	E	F	T	L	C	K	K	L	G	A	G	Y	F	G	E	V	F	E	A	L	W	K	.	.	.	.	.	G	Q	V	H	V	A	V	K	V	I	S	R	D	N	L	L	H	Q	H	T	F	Q	A	E	I
Query Conservation																																.	.	.	.	.
Alig confidence																																.	.	.	.	.												.	.	.	.
Template Conservation																																																.	.	.	.
Template Sequence		D	P	T	H	F	E	K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	.	.	.	.	P	H	I	A	D	L	K	K	E	I
Template Known Secondary structure			T	T	S			G	G	G											S	S										T	T	S	S	S		S										.	.	.	.
Template Predicted Secondary structure																																																.	.	.	.
Template SS confidence
		866	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.					.	.	.	.	.	.	.	.	920	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	A	M	K	K	L	R	H	K	H	I	L	S	L	Y	A	V	A	T	A	G	D	P	V	Y	I	I	T	E	L	M	P	K	G	N	L	L	Q	L	L	R	D	S	D	E	K	A	L	P	I	L	E	L	V	D	F	A	S	Q	V
Query Conservation
Alig confidence																								.																								.
Template Conservation																								.																								.
Template Sequence		E	I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	G	I	C	T	E	N	G	.	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	.	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I
Template Known Secondary structure						T				T	T	B												.									T	T		B					T	G	G	G	T	T	T	.
Template Predicted Secondary structure																								.																								.
Template SS confidence
		927	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.		.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.		.	.	.	.	.	.	.	.	980	.	.	.	.
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.		.	.	350	.	.	.	.	.
Predicted Secondary structure																																																					.
Query SS confidence																																																					.
Query Sequence		A	E	G	M	C	Y	L	E	S	Q	N	Y	I	H	R	D	L	A	A	R	N	V	L	V	T	E	N	N	L	C	K	V	G	D	F	G	L	A	R	L	V	K	E	D	I	Y	L	S	H	E	H	.	N	V	P	Y	K	W	T	A
Query Conservation																																																					.
Alig confidence																																																					.
Template Conservation
Template Sequence		C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A	I	E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A
Template Known Secondary structure											T	T				S			S	G	G	G						T	T								T	T						T	T					S			T	T			G	G	G
Template Predicted Secondary structure
Template SS confidence
		988	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.
		356	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.																.	390	.	.	.	.	.	.	.	.	.	400
Predicted Secondary structure																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		P	E	A	L	S	R	G	H	Y	S	I	K	S	D	V	W	S	F	G	V	L	L	H	E	I	F	S	R	G	Q	M	P	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	G	M	S	N	H	E	T	F	L	R	V
Query Conservation																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																													.						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																													.
Template Sequence		P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	.	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T	R	L	V	N	T	L
Template Known Secondary structure																												T	.	T	T		G	G	G												S			G	G	G
Template Predicted Secondary structure																													.
Template SS confidence
		1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.		.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	A	G	Y	R	M	P	C	P	L	E	C	P	P	N	I	H	K	L	M	L	S	C	W	S	R	D	P	K	Q	R	P	C	F	K	D	L	C	E	K	L	T	G	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L
Template Known Secondary structure			T	T							T	T												T			S	S	G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		1109	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D