Job Description Q64434 Confidence 100.00% Date Wed Jul 10 14:13:37 BST 2013 Rank 226 Aligned Residues 251 % Identity 31% Template c3c1xA_ PDB info PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor Resolution 2.17 Å

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		179	180	.	.	.	.	.	.	.	.	.	190			.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.					.	.	.	.	.	220	.		.	.	.	.	.	.	.	.	230	.
Predicted Secondary structure														.	.																									.	.	.	.								.
Query SS confidence														.	.																									.	.	.	.								.
Query Sequence		P	H	W	D	D	W	E	R	P	R	E	E	.	.	F	T	L	C	K	K	L	G	A	G	Y	F	G	E	V	F	E	A	L	W	K	G	Q	V	.	.	.	.	H	V	A	V	K	V	I	.	S	R	D	N	L	L	H	Q	H	T
Query Conservation														.	.																									.	.	.	.								.
Alig confidence														.	.																									.	.	.	.								.
Template Conservation
Template Sequence		Q	A	V	Q	H	V	V	I	G	P	S	S	L	I	V	H	F	N	E	V	I	G	R	G	H	F	G	C	V	Y	H	G	T	L	L	D	N	D	G	K	K	I	H	C	A	V	K	S	L	N	R	I	T	D	I	G	E	V	S	Q
Template Known Secondary structure			T	T	T	T	T	B			S	T	T													S	S	S										T	T	T												S		S		S
Template Predicted Secondary structure
Template SS confidence
		1064	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.
		232	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	Q	A	E	I	Q	A	M	K	K	L	R	H	K	H	I	L	S	L	Y	A	V	A	T	A	G	D	P	V	Y	I	I	T	E	L	M	P	K	G	N	L	L	Q	L	L	R	D	S	D	E	K	A	L	P	I	L	E	L	V	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	L	T	E	G	I	I	M	K	D	F	S	H	P	N	V	L	S	L	L	G	I	C	L	R	S	E	G	S	P	L	V	V	L	P	Y	M	K	H	G	D	L	R	N	F	I	R	N	E	T	H	N	P	T	V	K	D	L	I	G
Template Known Secondary structure							T	T	S	T	T				T	T	B											S	S										T	T		B								T	T				B
Template Predicted Secondary structure
Template SS confidence
		1124	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.
		292	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	A	S	Q	V	A	E	G	M	C	Y	L	E	S	Q	N	Y	I	H	R	D	L	A	A	R	N	V	L	V	T	E	N	N	L	C	K	V	G	D	F	G	L	A	R	L	V	K	E	D	I	Y	L	S	H	E	H	N	V	P	Y
Query Conservation
Alig confidence																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		F	G	L	Q	V	A	K	G	M	K	F	L	A	S	K	K	F	V	H	R	D	L	A	A	R	N	C	M	L	D	E	K	F	T	V	K	V	A	D	F	L	P	V	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure																T	T				S				G	G	G					T	T											G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1184	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	W	T	A	P	E	A	L	S	R	G	H	Y	S	I	K	S	D	V	W	S	F	G	V	L	L	H	E	I	F	S	R	G	Q	M	P	Y	P	G	M	S	N	H	E	T	F	L	R	V	D	A	G	Y	R	M	P	C	P	L	E
Query Conservation
Alig confidence		.
Template Conservation		.
Template Sequence		.	W	M	A	L	E	S	L	Q	T	Q	K	F	T	T	K	S	D	V	W	S	F	G	V	L	L	W	E	L	M	T	R	G	A	P	P	Y	P	D	V	N	T	F	D	I	T	V	Y	L	L	Q	G	R	R	L	L	Q	P	E	Y
Template Known Secondary structure		.	G	S																												T	T	S			S		T	T	S		S	S								T	T							T	T
Template Predicted Secondary structure		.
Template SS confidence
			1249	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.
		412	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	P	P	N	I	H	K	L	M	L	S	C	W	S	R	D	P	K	Q	R	P	C	F	K	D	L	C	E	K	L	T	G	I	T	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	P	D	P	L	Y	E	V	M	L	K	C	W	H	P	K	A	E	M	R	P	S	F	S	E	L	V	S	R	I	S	A	I	F	S
Template Known Secondary structure														T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1308	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D