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Job DescriptionQ64434
Confidence100.00%DateWed Jul 10 14:13:37 BST 2013
Rank18Aligned Residues263
% Identity39%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å
Model Dimensions (Å)X:62.535 Y:52.051 Z:41.298

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   182.......190.........200.........210 .........220.... .....230....
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Query Sequence  DDWERPREEFTLCKKLGAGYFGEVFEALW. . . . . . KGQVHVAVKVISRD. NLLHQHTFQA
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Template Sequence  PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLS
Template Known Secondary structure  TTTB

GGG
SSSTGGG
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TT

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   715....720.........730.........740.........750.........760.........770....
 
   235....240.........250.........260.........270.........280. .......
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Query Sequence  EIQAMKKLRHKHILSLYAVATAGDPVYIITELMPKGNLLQLLRDSDE. . . . . . KALPILE
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Template Sequence  EFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGD
Template Known Secondary structure  TT


TTB


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TT
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   775....780.........790.........800.........810.........820.........830....
 
   289290.........300.........310.........320.........330.........340.......
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Query Sequence  LVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVGDFGLARLVKEDIYLSHEH.
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Template Sequence  LISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQ
Template Known Secondary structure  TT



SGGGTTT


TT

TTTS

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   851........860.........870.........880.........890.........900.........910
 
   348.350.........360.........370.........380.........390.........400......
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Query Sequence  . NVPYKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVDAGYRM
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Template Sequence  GRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRM
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   911........920.........930.........940.........950.........960.........970
 
   407..410.........420.........430.........440....
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Query Sequence  PCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLTGI
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Template Sequence  ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM
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TT

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   971........980.........990.........1000........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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