Job Description Q64434 Confidence 100.00% Date Wed Jul 10 14:13:37 BST 2013 Rank 6 Aligned Residues 421 % Identity 44% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:82.877 Y:69.626 Z:51.530

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		12	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	Y	V	G	L	W	D	F	K	A	R	T	D	E	E	L	S	F	Q	A	G	D	L	L	H	V	T	K	K	E	E	L	W	W	W	A	T	L	L	D	A	E	G	K	A	L	A	E	G	Y	V	P	H	N	Y	L	A	E	K	E
Query Conservation
Alig confidence																																		.										.	.	.
Template Conservation																																		.										.	.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	S	G	E	.	W	W	K	A	R	S	L	A	T	.	.	.	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T										T	T	.							T	T	T	.	.	.								G	G	G				T	T
Template Predicted Secondary structure																																		.										.	.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.		.	.	.	.	.	.	.	100	.				.	.	.	.	.	.	.	.	110	.	.	.	.	.	.
		72	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.						120	.	.	.	.	.	.
Predicted Secondary structure																																																		.	.	.	.	.
Query SS confidence																																																		.	.	.	.	.
Query Sequence		T	V	E	S	E	P	W	F	F	G	C	I	S	R	S	E	A	M	H	R	L	Q	A	E	D	N	S	K	G	A	F	L	I	R	V	S	Q	K	P	G	A	D	Y	V	L	S	V	R	.	.	.	.	.	D	A	Q	A	V	R	H
Query Conservation																																																		.	.	.	.	.
Alig confidence																																																		.	.	.	.	.
Template Conservation
Template Sequence		S	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H
Template Known Secondary structure		S	G	G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T											T	T	T
Template Predicted Secondary structure
Template SS confidence
		117	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
		127	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	I	W	K	N	N	E	G	R	L	H	L	N	E	A	V	S	F	S	N	L	S	E	L	V	D	Y	H	K	T	Q	S	L	S	H	G	L	Q	L	S	M	P	C	W	K	H	K	T	E	P	L	P	H	W	D	D	W	E	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	W	E	K	D	A	W	E	I
Template Known Secondary structure					B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B												T	T		S	B
Template Predicted Secondary structure
Template SS confidence
		177	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	R	E	E	F	T	L	C	K	K	L	G	A	G	Y	F	G	E	V	F	E	A	L	W	K	G	Q	V	H	V	A	V	K	V	I	S	R	D	N	L	L	H	Q	H	T	F	Q	A	E	I	Q	A	M	K	K	L	R	H	K	H
Query Conservation
Alig confidence																																					.
Template Conservation																																					.
Template Sequence		P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	.	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K
Template Known Secondary structure			G	G	G											T	T									T	T	T									.				S	S														T				T	T
Template Predicted Secondary structure																																					.
Template SS confidence
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.		.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
		247	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	L	S	L	Y	A	V	A	T	A	G	D	P	V	Y	I	I	T	E	L	M	P	K	G	N	L	L	Q	L	L	R	D	S	D	E	K	A	L	P	I	L	E	L	V	D	F	A	S	Q	V	A	E	G	M	C	Y	L	E	S	Q
Query Conservation
Alig confidence										.
Template Conservation										.
Template Sequence		L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R
Template Known Secondary structure		B								.		S	S	S									T	T		B							S	T	T	G	G	G																							T
Template Predicted Secondary structure										.
Template SS confidence
		296	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.
		307	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	Y	I	H	R	D	L	A	A	R	N	V	L	V	T	E	N	N	L	C	K	V	G	D	F	G	L	A	R	L	V	K	E	D	I	Y	L	S	H	E	H	N	V	P	Y	K	W	T	A	P	E	A	L	S	R	G	H	Y	S	I
Query Conservation
Alig confidence																																	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	V	I	.	.	.	.	.	.	.	.	.	.	.	.	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I
Template Known Secondary structure		T				S			S	G	G	G					T	T								T	T	G	G	G	T		.	.	.	.	.	.	.	.	.	.	.	.		G	G	G	S
Template Predicted Secondary structure																																	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.													.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.
		367	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	S	D	V	W	S	F	G	V	L	L	H	E	I	F	S	R	G	Q	M	P	Y	P	G	M	S	N	H	E	T	F	L	R	V	D	A	G	Y	R	M	P	C	P	L	E	C	P	P	N	I	H	K	L	M	L	S	C	W	S	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N
Template Known Secondary structure																	T	T	T			S	S	T	T												T	T							T	T													T		S
Template Predicted Secondary structure
Template SS confidence
		416	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.
		427	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450
Predicted Secondary structure
Query SS confidence
Query Sequence		D	P	K	Q	R	P	C	F	K	D	L	C	E	K	L	T	G	I	T	R	Y	E	N	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S
Template Known Secondary structure		S	G	G	G	S												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		476	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.