Job Description Q64434 Confidence 100.00% Date Wed Jul 10 14:13:37 BST 2013 Rank 3 Aligned Residues 433 % Identity 38% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å Model Dimensions (Å) X:77.396 Y:74.725 Z:52.406

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		11	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Predicted Secondary structure
Query SS confidence
Query Sequence		P	K	Y	V	G	L	W	D	F	K	A	R	T	D	E	E	L	S	F	Q	A	G	D	L	L	H	V	T	K	K	E	E	L	W	W	W	A	T	L	L	D	A	E	G	K	A	L	A	E	G	Y	V	P	H	N	Y	L	A	E	K
Query Conservation
Alig confidence																																												.	.	.	.
Template Conservation																																												.	.	.	.
Template Sequence		N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	T	K	.	.	.	.	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V
Template Known Secondary structure		T					S	S		B				S	T	T	B			B		T	T										T	T	S	S							S	.	.	.	.	S							G	G	G				S
Template Predicted Secondary structure																																												.	.	.	.
Template SS confidence
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.					.	.	.	.	.	130	.	.	.	.	.	.	.	.
		71	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130
Predicted Secondary structure
Query SS confidence
Query Sequence		E	T	V	E	S	E	P	W	F	F	G	C	I	S	R	S	E	A	M	H	R	L	Q	A	E	D	N	S	K	G	A	F	L	I	R	V	S	Q	K	P	G	A	D	Y	V	L	S	V	R	D	A	Q	A	V	R	H	Y	R	I	W
Query Conservation
Alig confidence																									.	.
Template Conservation																									.	.
Template Sequence		N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	.	.	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	R	Y	E	G	R	V	Y	H	Y	R	I	N
Template Known Secondary structure		S	S	G	G	G	S	T	T														G	G	.	.	G			T	T								S	S	S	T	T									T	T
Template Predicted Secondary structure																									.	.
Template SS confidence
		139	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.			.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.
		131	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.					.	180	.	.	.	.	.	.
Predicted Secondary structure																																																		.	.	.	.
Query SS confidence																																																		.	.	.	.
Query Sequence		K	N	N	E	G	R	L	H	L	N	E	A	V	S	F	S	N	L	S	E	L	V	D	Y	H	K	T	Q	S	L	S	H	G	L	Q	L	S	M	P	C	W	K	H	K	T	E	P	L	.	.	.	.	P	H	W	D	D	W	E	R
Query Conservation																																																		.	.	.	.
Alig confidence																																																		.	.	.	.
Template Conservation
Template Sequence		T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M
Template Known Secondary structure				T	T	S				S	S	T	T	S		B	S	S									T	T			T	T	S	S	S										S					S	S	S		S	S	S	S			B
Template Predicted Secondary structure
Template SS confidence
		197	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.		.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Predicted Secondary structure																												.
Query SS confidence																												.
Query Sequence		P	R	E	E	F	T	L	C	K	K	L	G	A	G	Y	F	G	E	V	F	E	A	L	W	K	G	.	Q	V	H	V	A	V	K	V	I	S	R	D	N	L	L	H	Q	H	T	F	Q	A	E	I	Q	A	M	K	K	L	R	H	K
Query Conservation																												.
Alig confidence																												.										.
Template Conservation																																						.
Template Sequence		E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	.	K	E	D	T	M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P
Template Known Secondary structure			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T									.		S	S	S	S																		T
Template Predicted Secondary structure																																						.
Template SS confidence
		257	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.		.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
		246	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	I	L	S	L	Y	A	V	A	T	A	G	D	P	V	Y	I	I	T	E	L	M	P	K	G	N	L	L	Q	L	L	R	D	S	D	E	K	A	L	P	I	L	E	L	V	D	F	A	S	Q	V	A	E	G	M	C	Y	L	E	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K
Template Known Secondary structure		T	B									S	S	S	S									T	T		B								S		T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.
		306	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.		.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.
Predicted Secondary structure																																											.
Query SS confidence																																											.
Query Sequence		Q	N	Y	I	H	R	D	L	A	A	R	N	V	L	V	T	E	N	N	L	C	K	V	G	D	F	G	L	A	R	L	V	K	E	D	I	Y	L	S	H	E	.	H	N	V	P	Y	K	W	T	A	P	E	A	L	S	R	G	H	Y
Query Conservation																																											.
Alig confidence																																											.
Template Conservation
Template Sequence		K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F
Template Known Secondary structure		T	T				S			S	G	G	G					G	G	G							T	T						T	T							T	T					G	G	G
Template Predicted Secondary structure
Template SS confidence
		376	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.
		365	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	I	K	S	D	V	W	S	F	G	V	L	L	H	E	I	F	S	R	G	Q	M	P	Y	P	G	M	S	N	H	E	T	F	L	R	V	D	A	G	Y	R	M	P	C	P	L	E	C	P	P	N	I	H	K	L	M	L	S	C	W
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W
Template Known Secondary structure																			T	T	S			S	S	T	T			T	T	T							T	T							T	T													T
Template Predicted Secondary structure
Template SS confidence
		436	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.
		425	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450
Predicted Secondary structure
Query SS confidence
Query Sequence		S	R	D	P	K	Q	R	P	C	F	K	D	L	C	E	K	L	T	G	I	T	R	Y	E	N	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E	S	S	I
Template Known Secondary structure			S	S	G	G	G	S												T	S		S	S	S
Template Predicted Secondary structure
Template SS confidence
		496	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.