Return to main results Retrieve Phyre Job Id

Job DescriptionP35991
Confidence100.00%DateWed Jul 10 14:27:18 BST 2013
Rank131Aligned Residues331
% Identity26%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å
Model Dimensions (Å)X:49.052 Y:59.834 Z:55.768

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.........30.........40.........50.........60..
Predicted Secondary structure 



























Query SS confidence 



























































Query Sequence  AVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKIT
Query Conservation       
 
 

   
      
 
 
 


    
 

               
 
  
 
Alig confidence 















.....
















....

















Template Conservation       
 
 
      ..... 

 
   
        ....           
    
 
Template Sequence  AIVKEGWLHKRGEYIK. . . . . TWRPRYFLLKNDGTFIG. . . . YKERPQDVEAPLNNFSVA
Template Known Secondary structure 

SSS
.....
TTSB....SS

S





GGGB
T
Template Predicted Secondary structure 





.....



....














Template SS confidence 



























































   5....10.........20 .........30....... ..40.........50.....
 
   63......70.........80.........90.........100......... 110.........120.
Predicted Secondary structure 



































.


Query SS confidence 














































.











Query Sequence  CVETVIPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEG. PLYVFSPTEELR
Query Conservation   

 
                                  


     . 

  
     
Alig confidence 









.........................











.











Template Conservation            .........................    
 
                  
Template Sequence  QCQLMKTERP. . . . . . . . . . . . . . . . . . . . . . . . . RPNTFIIRCLQWTTVIERTFTPEER
Template Known Secondary structure  T



B

SS.........................SSS
BTT

TTGG
Template Predicted Secondary structure 





.........................







Template SS confidence 



























































   5960........ .70.........80.........90...
 
   122.......130.........140.........150.........160.........170.........180.
Predicted Secondary structure 











































Query SS confidence 



























































Query Sequence  KRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSSH
Query Conservation    

 


     
       


      
 

        

             
  
Alig confidence 



















........................................
Template Conservation    
                 ........................................
Template Sequence  EEWTTAIQTVADGLKKQVTM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  GTT


T........................................
Template Predicted Secondary structure 














........................................
Template SS confidence 



























































   97..100.........110......
 
   182.......190.........200.........210.........220.........230.........240.
Predicted Secondary structure 




















































Query SS confidence 



























































Query Sequence  RKTKKPLPPTPEEDQILKKPLPPEPTAAPISTTELKKVVALYDYMPMNANDLQLRKGEEY
Query Conservation   
    

  
        
 
  
   
          

          
    
   
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
Template SS confidence 



























































  
 
   242.......250.........260.........270.........280.........290.........300.
Predicted Secondary structure 















































Query SS confidence 



























































Query Sequence  FILEESNLPWWRARDKNGQEGYIPSNYITEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKE
Query Conservation   

      

      
  
 



 
      

   



 


 


 

      
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
Template SS confidence 



























































  
 
   302.......310.........320.........330.........340.........350.........360.
Predicted Secondary structure 




























Query SS confidence 



























































Query Sequence  GGFIVRDSSKAGKYTVSVFAKSTGEPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINY
Query Conservation 
 



 

  
   


           


  
     
   
     
 

 


  
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
Template SS confidence 



























































  
 
   362.......370.........380.........390.........400.........410.........420.
Predicted Secondary structure 


































Query SS confidence 



























































Query Sequence  HQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKW
Query Conservation        

   
                       
          

 
 

 
     
Alig confidence  ......................................





















Template Conservation  ......................................  
     

 
 

 

    
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NEFEYLKLLGKGTFGKVILVKE
Template Known Secondary structure  ......................................TSTT
Template Predicted Secondary structure  ......................................





Template SS confidence 



























































   148.150.........160.........
 
   422. ......430.........440.........450.........460.........470.........480
Predicted Secondary structure 

.



















Query SS confidence 

.
























































Query Sequence  RG. QYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANG
Query Conservation    .   



           
  
   
  
 
 


 
 
         

 
    
Alig confidence 

.









......








































Template Conservation         


   ......
    
  

  
 




             



     
Template Sequence  KATGRYYAMKILK. . . . . . KEVIVANRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGG
Template Known Secondary structure  TTT

......GGGS



GGGTS

TTB


SS

SS
Template Predicted Secondary structure 



......











Template SS confidence 



























































   170.........180.. .......190.........200.........210.........220...
 
   481........490.........500.........510.... .....520.........530.........
Predicted Secondary structure 






.














Query SS confidence 

































.
























Query Sequence  CLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLES. KQFLHRDLAARNCLVNDQGVVKVSD
Query Conservation 

   
      
       
  


 

 


 .  





   



     


 
Alig confidence 









.






















.
























Template Conservation   
        .             
            
                      
Template Sequence  ELFFHLSRER. VFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITD
Template Known Secondary structure  BS.S

TS







GGG
TTS


Template Predicted Secondary structure 









.




















Template SS confidence 



























































   234.....240... ......250.........260.........270.........280.........290..
 
   540.........550.........560.........570.........580.........590.........
Predicted Secondary structure 



























Query SS confidence 



























































Query Sequence  FGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYE
Query Conservation 



                
  
 


       
 





 

 
 

 
 
  
  
Alig confidence 






...............






























.





Template Conservation 

     ...............                 

 


 

 

  .
  

 
Template Sequence  FGLCKEP. . . . . . . . . . . . . . . EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFY
Template Known Secondary structure 

SS


...............
SS
TT



T.SS
SS
Template Predicted Secondary structure 



...............

















.





Template SS confidence 



























































   293...... 300.........310.........320.........330 ......
 
   600.........610.........620.........630.........640. ........
Predicted Secondary structure 



















.....

Query SS confidence 









































. . . . .







Query Sequence  RFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADER. . . . . PSFKILLS
Query Conservation            
  
     
   
  
  

  

  

  
.....

   
  
Alig confidence 














.

























.....







Template Conservation            
    .       
    


   
  

  
     

  
 
 
Template Sequence  NQDHEKLFELILMEE. IRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure 
SS

.



TT

T
SSTTTSTT
STTTT
Template Predicted Secondary structure 





.



















Template SS confidence 






















































   351........360..... ....370.........380.........390.........400....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D