Job Description P35991 Confidence 100.00% Date Wed Jul 10 14:27:18 BST 2013 Rank 91 Aligned Residues 259 % Identity 30% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

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		396	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.						.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.			440	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.	.	.	.	.																		.	.
Query SS confidence																													.	.	.	.	.																		.	.
Query Sequence		E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	.	.	.	.	.	G	Q	Y	D	V	A	I	K	M	I	R	E	G	S	M	S	E	.	.	D	E	F	I	E	E	A	K	V
Query Conservation																													.	.	.	.	.																		.	.
Alig confidence																													.	.	.	.	.																		.	.
Template Conservation
Template Sequence		V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	H	R	S	G	W	K	Q	E	I	D	I
Template Known Secondary structure					G	G	G											S	S										T	T	S	S	S												S	S
Template Predicted Secondary structure
Template SS confidence
		891	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950
		449	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	M	N	L	S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	R	T	L	Y	H	E	H	I	I	K	Y	K	G	C	C	E	D	A	G	A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	H	S	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G
Template Known Secondary structure								T	T	B										T	T	T	T										T	T		B					G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		951	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010
		509	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	L	S	R	Y	V	L	D	D	E	Y	T	S	S	V	G	S	K	F	P	V	R	W	S	P	P	E	V
Query Conservation
Alig confidence																																																				.	.
Template Conservation																																																				.	.
Template Sequence		M	A	Y	L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	R	V	G	D	S	P	.	.	V	F	W	Y	A	P	E	C
Template Known Secondary structure								T	T				S			S	G	G	G						T	T								T	T						T	T				B						.	.	G	G	G
Template Predicted Secondary structure																																																				.	.
Template SS confidence
		1011	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060			.	.	.	.	.	.	.	.
		569	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.																600	.	.	.	.	.	.	.	.	.	610	.	.	.
Predicted Secondary structure																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		L	M	Y	S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	F	T	N	S	E	T	A	E	H	I	A	Q	G
Query Conservation																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																										.							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																										.
Template Sequence		L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	A	Q	G	Q	M	T	V	L	R	L	T	E	L	L	E	R	G
Template Known Secondary structure				S		B																			T	.	T	T		G	G	G	S											S	T	T	G	G	G											T	T
Template Predicted Secondary structure																										.
Template SS confidence
		1073	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.		.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.
		614	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	L	Y	R	P	H	L	A	S	E	R	V	Y	T	I	M	Y	S	C	W	H	E	K	A	D	E	R	P	S	F	K	I	L	L	S	N	I	L	D	V	M	D	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	R	L	P	R	P	D	K	C	P	A	E	V	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	E	N	L	I	P	I	L	K	T	V	H	E	K
Template Known Secondary structure								T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1132	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D