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Job DescriptionP35991
Confidence100.00%DateWed Jul 10 14:27:18 BST 2013
Rank87Aligned Residues243
% Identity100%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   392.......400.........410.........420.........430.........440.........450.
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Query Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIREGSMSEDEFIEEAKVMMN
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKE. . . . . . . FIEEAKVMMN
Template Known Secondary structure 
GGGB

GGGSTTSS
TTT


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TT
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   392.......400.........410.........420.........430.... .....440....
 
   452.......460.........470.........480.........490.........500.........510.
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Query Sequence  LSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEY
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Template Sequence  LSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEY
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TTB


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TT
GGG


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   452.......460.........470.........480.........490.........500.........510.
 
   512.......520.........530.........540.........550.........560.........570.
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Query Sequence  LESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMY
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Template Sequence  LESKQFLHRDLAARNCLVNDQGVVKVSDFGFPV. . . . . . . . . . . . . . . . . RWSPPEVLMY
Template Known Secondary structure  TT


S

SGGG
TT







G.................GG

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   512.......520.........530.........540.... .....550....
 
   572.......580.........590.........600.........610.........620.........630.
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Query Sequence  SKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASERVYTIMY
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Template Sequence  SKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
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TTS

TTTTS
TT





TTS
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   572.......580.........590.........600.........610.........620.........630.
 
   632.......640.........650........
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Query Sequence  SCWHEKADERPSFKILLSNILDVMDEE
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Template Sequence  SCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


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   632.......640.........650........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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