|   |   |
393 | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 430 | . | . | . | |
. | . | . | . | . | . | 440 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | S | W | E | I | D | P | K | D | L | T | F | L | K | E | L | G | T | G | Q | F | G | V | V | K | Y | G | K | W | R | G | . |
. |
. |
. |
. |
Q | Y | D | V | A | I | K | M | I | R | . |
E | G | S | M | S | E | D | E | F | I | E | E | A |
| Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|
|
|
|   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
D | P | T | Q | F | E | E | R | H | L | K | F | L | Q | Q | L | G | K | G | N | F | G | S | V | E | M | C | R | Y | D | P | L | Q | D | N | T | G | E | V | V | A | V | K | K | L | Q | H | S | T | E | E | H | L | R | D | F | E | R | E | I |
| Template Known Secondary structure |   |
| T | T |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |
| T | T | S | S | S |
|
|
|  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
447 | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | V | M | M | N | L | S | H | E | K | L | V | Q | L | Y | G | V | C | T | K | Q | R | P | I | F | I | I | T | E | Y | M | A | N | G | C | L | L | N | Y | L | R | E | M | R | H | R | F | Q | T | Q | Q | L | L | E | M | C | K | D | V | C |
| Query Conservation |   |
  |   |
|   |   |
|   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | I | L | K | S | L | Q | H | D | N | I | V | K | Y | K | G | V | C | Y | S | . |
. |
N | L | K | L | I | M | E | Y | L | P | Y | G | S | L | R | D | Y | L | Q | K | H | K | E | R | I | D | H | I | K | L | L | Q | Y | T | S | Q | I | C |
| Template Known Secondary structure |   |
 |  |  |  | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |
|
| T | T |
| B |  |  |  |  | T | T | T | S | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | |
|
920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . |
|   |
|   |   |
507 | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | A | M | E | Y | L | E | S | K | Q | F | L | H | R | D | L | A | A | R | N | C | L | V | N | D | Q | G | V | V | K | V | S | D | F | G | L | S | R | Y | V | L | D | D | E | Y | T | S | S | V | G | S | K | F | P | V | R | W | S | P | P |
| Query Conservation |   |
  |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|   |   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
K | G | M | E | Y | L | G | T | K | R | Y | I | H | R | D | L | A | T | R | N | I | L | V | E | N | E | N | R | V | K | I | G | D | F | G | L | T | K | V | L | P | Q | D | K | E | K | V | K | E | P | G | E | S | P | I | F | W | Y | A | P |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  |  |  | T | T |  |  |  |  |
|
|
| T | T |
|  |  |
|
| T | T |
|
|
|
|
|
| S | S |
|
|
| G | G | G |
|
|  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
962 | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . |
|   |
|   |   |
567 | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 610 |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | V | L | M | Y | S | K | F | S | S | K | S | D | I | W | A | F | G | V | L | M | W | E | I | Y | S | L | G | K | M | P | Y | E | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | T | N | S | E | T | A | E | H | I |
| Query Conservation |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |
|
|   |
| . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | S | L | T | E | S | K | F | S | V | A | S | D | V | W | S | F | G | V | V | L | Y | E | L | F | T | . |
Y | I | E | K | S | K | S | P | P | A | E | F | M | R | M | I | G | N | D | K | Q | G | Q | M | I | V | F | H | L | I | E | L | L |
| Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | T |
| G | G | G | S |  |  |  |  |  |  |  |  |  |
| S |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1024 | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | |
1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . |
|   |
|   |   |
611 | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | Q | G | L | R | L | Y | R | P | H | L | A | S | E | R | V | Y | T | I | M | Y | S | C | W | H | E | K | A | D | E | R | P | S | F | K | I | L | L | S | N | I | L | D | V | M | D | E |
| Query Conservation |   |
  |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |
|   |   |   |
| Template Sequence |   |
K | N | N | G | R | L | P | R | P | D | G | C | P | D | E | I | Y | M | I | M | T | E | C | W | N | N | N | V | N | Q | R | P | S | F | R | D | L | A | L | R | V | D | Q | I | R | D | Q |
| Template Known Secondary structure |   |
 | T | T |
|
|
|
|
|
| T | T |
|
| T | T |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1083 | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . |
|   |