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Job DescriptionP35991
Confidence100.00%DateWed Jul 10 14:27:18 BST 2013
Rank212Aligned Residues236
% Identity25%Templatec3fmeA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6; PDBTitle: crystal structure of human mitogen-activated protein kinase kinase 62 (mek6) activated mutant (s207d, t211d)
Resolution2.26 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   396...400.........410.........420.. .......430.........440.........450....
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Query Sequence  EIDPKDLTFLKELGTGQFGVVKYGKWR. GQYDVAIKMIREGSMSEDEFIEEAKVMMNLSH
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Template Sequence  EVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRNSQEQKRLLMDLDISMRTVDC
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GGG
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   47..50.........60.........70.........80.........90.........100......
 
   455....460.........470.........480....... ..490.........500.........510..
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Query Sequence  EKLVQLYGVCTKQRPIFIITEYMANGCLLNYLR. . EMRHRFQTQQLLEMCKDVCEAMEYL
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Template Sequence  PFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHL
Template Known Secondary structure  TTB


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   110.........120.........130.........140.........150.........160.........
 
   513 ......520.........530.........540.........550.........560.........570.
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Query Sequence  E. SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMY
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Template Sequence  HSKLSVIHRDVKPSNVLINALGQVKMCDFAGCK. . . . . . . . . . . . . . . . . PYMAPERINP
Template Known Secondary structure  S






SGGG

TT

B






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S
S
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   170.........180.........190.........200.. .......210..
 
   572 .......580.........590.........600.. .......610.........620.......
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Query Sequence  S. . KFSSKSDIWAFGVLMWEIYSLGKMPYERFT. . NSETAEHIAQGLRLYRPHLASERVY
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Template Sequence  ELNQYSVKSDIWSLGITMIELAI. LRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFV
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TT


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   228.230.........240.........250 .........260.........270.........280......
 
   628.630.........640.........
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Query Sequence  TIMYSCWHEKADERPSFKILLS
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Template Sequence  DFTSQCLKKNSKERPTYPELMQ
Template Known Secondary structure  T
SSGGGS

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   289290.........300.........310
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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