|   |   |
397 | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | |
. | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | D | P | K | D | L | T | F | L | K | E | L | G | T | G | Q | F | G | V | V | K | Y | G | K | W | R | . |
G | Q | Y | D | V | A | I | K | M | I | R | E | G | S | M | S | E | D | E | F | I | E | E | A | K | V | M | M | N | L | S | H | E |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |
|   |
|   |   |   |
| . | . |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
| Template Sequence |   |
V | Q | L | N | Q | Y | T | L | K | D | E | I | . |
. |
G | K | Y | G | V | V | K | L | A | Y | N | E | N | D | N | T | Y | Y | A | M | K | V | L | S | K | K | . |
. |
. |
. |
E | Q | V | Y | Q | E | I | A | I | L | K | K | L | D | H | P |
| Template Known Secondary structure |   |
|  |  | T | T |  |  |  |  |  |  |  | . | . |  |
|
|
|  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  | T |
|
|
| T |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | |
|
. | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | |
|
|
|
. | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . |
|   |
|   |   |
456 | . | . | . | 460 | . | . | . | . | . | . | . | |
|
. | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | L | V | Q | L | Y | G | V | C | T | K | Q | . |
. |
R | P | I | F | I | I | T | E | Y | M | A | N | G | C | L | L | N | Y | L | R | E | M | R | H | R | F | Q | T | Q | Q | L | L | E | M | C | K | D | V | C | E | A | M | E | Y | L | E |
| Query Conservation |   |
|
|
|   |
|   |
|   |   |   |   |   | . | . |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|
| Template Sequence |   |
N | V | V | K | L | V | E | V | L | D | D | P | N | E | D | H | L | Y | M | V | F | E | L | V | N | Q | G | P | V | M | E | V | P | . |
. |
T | L | K | P | L | S | E | D | Q | A | R | F | Y | F | Q | D | L | I | K | G | I | E | Y | L | H |
| Template Known Secondary structure |   |
T | B |
|
|  |  |  |  |  |  |
| S | S | S | S |  |  |  |  |  |  |  |
|
| T | T |
| B | S |
|
| S | S | . | . |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | |
|
. | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
|   |
|   |   |
514 | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | K | Q | F | L | H | R | D | L | A | A | R | N | C | L | V | N | D | Q | G | V | V | K | V | S | D | F | G | L | S | R | Y | V | L | D | D | E | Y | T | S | S | V | G | S | K | F | P | V | R | W | S | P | P | E | V | L | M | Y | S | K |
| Query Conservation |   |
  |   |   |
|
|
|
|
|
|   |   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |
|   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
| Template Sequence |   |
Y | Q | K | I | I | H | R | D | I | K | P | S | N | L | L | V | G | E | D | G | H | I | K | I | A | D | F | G | V | S | N | E | F | K | G | S | D | A | L | L | S | N | T | V | . |
G | T | P | A | F | M | A | P | E | S | L | S | E | T | R |
| Template Known Secondary structure |   |
 | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |
| S | S | S | S |
|  |  |
|
|
|
| . | S |
| G | G | G |
|
| G | G | G |
|
| T | T |
|
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
306 | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
|   |
|   |   |
|
|
|
574 | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | |
. | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
F | S | S | K | S | D | I | W | A | F | G | V | L | M | W | E | I | Y | S | L | G | K | M | P | Y | E | R | F | T | N | S | E | T | A | E | H | I | A | Q | G | . |
L | R | L | Y | R | P | H | L | A | S | E | R | V | Y | T | I |
| Query Conservation |   |
. | . | . |   |
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| . |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
| Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
K | I | F | S | G | K | A | L | D | V | W | A | M | G | V | T | L | Y | C | F | V | F | . |
G | Q | C | P | F | M | D | E | R | I | M | C | L | H | S | K | I | K | S | Q | A | L | E | F | P | D | Q | P | D | I | A | E | D | L | K | D | L |
| Template Known Secondary structure |   |
|
|  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| S | S | S |
|
|
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
365 | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
. | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . |
|   |
|   |   |
630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | Y | S | C | W | H | E | K | A | D | E | R | P | S | F | K | I | L | L | S |
| Query Conservation |   |
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
I | T | R | M | L | D | K | N | P | E | S | R | I | V | V | P | E | I | K | L |
| Template Known Secondary structure |   |
 |  |  |  | T |
| S |
| T | T | T | S |
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
424 | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . |
|   |