Job Description P35991 Confidence 100.00% Date Wed Jul 10 14:27:18 BST 2013 Rank 278 Aligned Residues 255 % Identity 17% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		397	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.		.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.
Predicted Secondary structure																												.
Query SS confidence																												.
Query Sequence		I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	.	G	Q	Y	D	V	A	I	K	M	I	R	E	G	S	M	S	E	D	E	F	I	E	E	A	K	V	M	M	N	L	S	H	E
Query Conservation																												.
Alig confidence																												.												.	.
Template Conservation																																								.	.
Template Sequence		G	E	Q	D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	N	N	N	E	K	C	I	I	K	I	L	K	.	.	P	V	K	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P
Template Known Secondary structure				G	G	G											S	S									T	T	T											.	.	S																			T
Template Predicted Secondary structure																																								.	.
Template SS confidence
		34	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.			.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
		456	.	.	.	460	.	.	.	.	.	.	.	.	.			470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.
Predicted Secondary structure																.	.
Query SS confidence																.	.
Query Sequence		K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	.	.	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E
Query Conservation																.	.
Alig confidence																.	.																		.	.	.	.
Template Conservation																																			.	.	.	.
Template Sequence		N	I	V	K	L	L	D	I	V	R	D	Q	H	S	K	T	P	S	L	I	F	E	Y	V	N	N	T	D	F	K	V	L	Y	.	.	.	.	P	T	L	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H
Template Known Secondary structure		T	B										T	T	T																			G	.	.	.	.	G	G
Template Predicted Secondary structure																																			.	.	.	.
Template SS confidence
		93	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.					.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.
		514	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.		530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.
Predicted Secondary structure																		.																																											.
Query SS confidence																		.																																											.
Query Sequence		S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	.	N	D	Q	G	V	V	K	V	S	D	F	G	L	S	R	Y	V	L	D	D	E	Y	T	S	S	V	G	S	K	F	P	V	R	W	S	P	P	E	V	L	M	Y	.
Query Conservation																		.																																											.
Alig confidence																		.																														.	.												.
Template Conservation																																																.	.
Template Sequence		S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A	E	F	Y	H	P	G	K	E	Y	N	V	R	V	A	S	.	.	R	Y	F	K	G	P	E	L	L	V	D	L
Template Known Secondary structure			T	T							S	G	G	G					T	T	T	T								T	T						T	T					S			S		.	.	G	G	G							T	T
Template Predicted Secondary structure																																																.	.
Template SS confidence
		149	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.			.	.	.	.	.	200	.	.	.	.	.	.
		572	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I	E	L	D
Template Known Secondary structure			S			T																	T		S	S	S	S			S	S																								T	T
Template Predicted Secondary structure
Template SS confidence
		207	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
																610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.			650	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																									.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																									.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	A	Q	G	L	R	L	Y	R	P	H	L	A	S	E	R	V	Y	T	I	M	Y	S	C	W	H	E	K	A	D	E	R	P	S	F	K	I	L	L	S	.	.	N	I	L	D
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																									.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																									.	.
Template Conservation
Template Sequence		P	Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T	H	P	Y	F	Q	Q
Template Known Secondary structure																G	G	G	G			T	T	T	G	G	G											T	T			S	S	T	T	T	S									S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		267	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.
		654	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	M	D	E	E	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	R	A	A	E	N
Template Known Secondary structure							T
Template Predicted Secondary structure
Template SS confidence
		327	.	.	330	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D