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Job DescriptionP35991
Confidence100.00%DateWed Jul 10 14:27:18 BST 2013
Rank20Aligned Residues265
% Identity36%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å
Model Dimensions (Å)X:53.426 Y:60.216 Z:41.531

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   393......400.........410.........420.. .......430......... 440....
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Query Sequence  GSWEIDPKDLTFLKELGTGQFGVVKYGKWR. . . . . . GQYDVAIKMIREGSMSE. . DEFIE
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Template Sequence  PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLS
Template Known Secondary structure  TTTB

GGG
SSSTGGG
SS

TT

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   715....720.........730.........740.........750.........760.........770....
 
   445....450.........460.........470.........480.........490 .......
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Query Sequence  EAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMR. . . . . . . HRFQTQQ
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Template Sequence  EFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTMGD
Template Known Secondary structure  TT


TTB


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TT
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   775....780.........790.........800.........810.........820.........830....
 
   498.500.........510.........520.........530.........540........ .550......
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Query Sequence  LLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLD. DEYTSSVG
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Template Sequence  LISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQ
Template Known Secondary structure  TT



SGGGTTT


TT

TTTS

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   851........860.........870.........880.........890.........900.........910
 
   557..560.........570.........580.........590.........600.........610......
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Query Sequence  SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL
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Template Sequence  GRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRM
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GGG



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   911........920.........930.........940.........950.........960.........970
 
   617..620.........630.........640.........650.......
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Query Sequence  YRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDE
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Template Sequence  ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK
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TT

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   971........980.........990.........1000.........1010.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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