Job Description P35991 Confidence 100.00% Date Wed Jul 10 14:27:18 BST 2013 Rank 4 Aligned Residues 430 % Identity 39% Template c2h8hA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Resolution 2.20 Å Model Dimensions (Å) X:63.390 Y:73.536 Z:49.975

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		219	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.		.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
Predicted Secondary structure																																								.
Query SS confidence																																								.
Query Sequence		V	V	A	L	Y	D	Y	M	P	M	N	A	N	D	L	Q	L	R	K	G	E	E	Y	F	I	L	E	E	S	N	L	P	W	W	R	A	R	D	.	K	N	G	Q	E	G	Y	I	P	S	N	Y	I	T	E	A	E	D	S	I	E
Query Conservation																																								.
Alig confidence																																								.																	.
Template Conservation																																																									.
Template Sequence		F	V	A	L	Y	D	Y	E	S	R	T	E	T	D	L	S	F	K	K	G	E	R	L	Q	I	V	N	N	T	E	G	D	W	W	L	A	H	S	L	S	T	G	Q	T	G	Y	I	P	S	N	Y	V	A	P	S	.	D	S	I	Q
Template Known Secondary structure					S	S		B				S	S	S	B			B		T	T									S	S	S	S							T	T	T								G	G	G				T	.	T	S	G	G
Template Predicted Secondary structure																																																									.
Template SS confidence
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140		.	.	.	.
		278	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.		300	.	.	.	.	.	.	.	.	.		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.
Predicted Secondary structure																								.											.
Query SS confidence																								.											.
Query Sequence		M	Y	E	W	Y	S	K	H	M	T	R	S	Q	A	E	Q	L	L	K	Q	E	G	.	K	E	G	G	F	I	V	R	D	S	.	S	K	A	G	K	Y	T	V	S	V	F	A	K	S	T	G	E	P	Q	G	V	I	R	H	Y	V
Query Conservation																								.											.
Alig confidence																								.											.																		.
Template Conservation																																																					.
Template Sequence		A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	N	A	K	.	G	L	N	V	K	H	Y	K
Template Known Secondary structure		G	S	T	T	B			S											T		T	T			T	T								S	S	S	T	T											T	T	T	.
Template Predicted Secondary structure																																																					.
Template SS confidence
		145	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.		.	.	.	.	200	.	.	.
		336	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	C	S	T	P	Q	S	Q	Y	Y	L	A	E	K	H	L	F	S	T	I	P	E	L	I	N	Y	H	Q	H	N	S	A	G	L	I	S	R	L	K	Y	P	V	S	K	Q	N	K	N	A	P	S	T	A	G	L	G	Y	G	S	W
Query Conservation
Alig confidence																																													.	.	.
Template Conservation																																													.	.	.
Template Sequence		I	R	K	L	D	S	G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	.	.	.	T	S	K	P	Q	T	Q	G	L	A	K	D	A	W
Template Known Secondary structure			B		.			S						T	T				S	S													T	T	S	S	S								.	.	.							S	S	S	S	T	T		S
Template Predicted Secondary structure																																													.	.	.
Template SS confidence
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.				.	.	.	250	.	.	.	.	.	.	.	.	.	260
		396	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	G	Q	Y	D	V	A	I	K	M	I	R	E	G	S	M	S	E	D	E	F	I	E	E	A	K	V	M	M	N	L	S	H	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q	V	M	K	K	L	R	H	E
Template Known Secondary structure		B			G	G	G											S	S									T	T	T										T	T	S	S																		T
Template Predicted Secondary structure
Template SS confidence
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
		456	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.		.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.
Predicted Secondary structure																																	.
Query SS confidence																																	.
Query Sequence		K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	.	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E	S
Query Conservation																																	.
Alig confidence												.																					.
Template Conservation												.
Template Sequence		K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R
Template Known Secondary structure		T	B									.	S	S	S									T	T								S					T	T
Template Predicted Secondary structure												.
Template SS confidence
		321	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.
		515	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	L	S	R	Y	V	L	D	D	E	Y	T	S	S	V	G	S	K	F	P	V	R	W	S	P	P	E	V	L	M	Y	S	K	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F
Template Known Secondary structure		T	T				S			S	G	G	G					G	G	G							T	T	S	T	T	T								T	T		S	T	T	S		G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
		575	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	G	L	R	L	Y	R	P	H	L	A	S	E	R	V	Y	T	I	M	Y	S	C	W
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	M	C	Q	C	W
Template Known Secondary structure																		T	T	T	T			S	S	T	T												T	T							T	T													T
Template Predicted Secondary structure
Template SS confidence
		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.
		635	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	E	K	A	D	E	R	P	S	F	K	I	L	L	S	N	I	L	D	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y
Template Known Secondary structure			S	S	G	G	G	S												T	S
Template Predicted Secondary structure
Template SS confidence
		500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.