Job Description P35991 Confidence 100.00% Date Wed Jul 10 14:27:18 BST 2013 Rank 1 Aligned Residues 452 % Identity 40% Template c2fo0A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase Resolution 2.27 Å Model Dimensions (Å) X:78.485 Y:80.197 Z:50.868

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		199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	K	P	L	P	P	E	P	T	A	A	P	I	S	T	T	E	L	K	K	V	V	A	L	Y	D	Y	M	P	M	N	A	N	D	L	Q	L	R	K	G	E	E	Y	F	I	L	E	E	S	N	L	P	W	W	R	A	R	D	K	N
Query Conservation
Alig confidence																.
Template Conservation																.
Template Sequence		A	R	W	N	K	E	N	L	L	A	G	P	S	E	.	N	D	P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	T	K
Template Known Secondary structure							T	T	T	T			G	G	G	.	S		T	T					S	S		B				S	T	T	B			B		T	T										T	T	S	S							T
Template Predicted Secondary structure																.
Template SS confidence
		65	.	.	.	.	70	.	.	.	.	.	.	.	.		.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.
		259	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.		310	.	.	.	.	.	.	.
Predicted Secondary structure																																																					.
Query SS confidence																																																					.
Query Sequence		G	Q	E	G	Y	I	P	S	N	Y	I	T	E	A	E	D	S	I	E	M	Y	E	W	Y	S	K	H	M	T	R	S	Q	A	E	Q	L	L	K	Q	E	G	K	E	G	G	F	I	V	R	D	S	.	S	K	A	G	K	Y	T	V
Query Conservation																																																					.
Alig confidence																.																									.												.
Template Conservation																.																									.
Template Sequence		N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	.	N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	.	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I
Template Known Secondary structure		T							G	G	G				T	.	T	S	G	G	G	S	T	T														T	S	S	.	S		T	T								S	S	S	T	T
Template Predicted Secondary structure																.																									.
Template SS confidence
		125	.	.	.	.	130	.	.	.	.	.	.	.	.		.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.		.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.
		318	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	V	F	A	K	S	T	G	E	P	Q	G	V	I	R	H	Y	V	V	C	S	T	P	Q	S	Q	Y	Y	L	A	E	K	H	L	F	S	T	I	P	E	L	I	N	Y	H	Q	H	N	S	A	G	L	I	S	R	L	K	Y	P	V
Query Conservation
Alig confidence						.	.	.	.	.	.
Template Conservation						.	.	.	.	.	.
Template Sequence		S	L	R	Y	.	.	.	.	.	.	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A
Template Known Secondary structure						.	.	.	.	.	.	T	T											T	T	S				S	S	T	T			B	S	S													T	T	S	S	S
Template Predicted Secondary structure						.	.	.	.	.	.
Template SS confidence
		183	.	.	.							.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
		378	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.		.	.	.	.	.	.	430	.	.	.	.	.	.
Predicted Secondary structure																																																.
Query SS confidence																																																.
Query Sequence		S	K	Q	N	K	N	A	P	S	T	A	G	L	G	Y	G	S	W	E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	G	.	Q	Y	D	V	A	I	K	M	I	R	E	G	S
Query Conservation																																																.
Alig confidence																																																.
Template Conservation
Template Sequence		P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T
Template Known Secondary structure										S	S	S		S	S	T	T			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T										T	T	S
Template Predicted Secondary structure
Template SS confidence
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
		437	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.		490	.	.	.	.	.
Predicted Secondary structure																																																							.
Query SS confidence																																																							.
Query Sequence		M	S	E	D	E	F	I	E	E	A	K	V	M	M	N	L	S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	.	R	H	R	F	Q	T
Query Conservation																																																							.
Alig confidence																																																							.
Template Conservation
Template Sequence		M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A
Template Known Secondary structure																				T	T	B									S	S	S	S									T	T		B								S		T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
		496	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	L	S	R	Y	V	L	D	D	E	Y	T	S	S	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A
Template Known Secondary structure																					T	T				S			S	G	G	G					G	G	G							T	T						S	S							T
Template Predicted Secondary structure
Template SS confidence
		357	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
		556	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	S	K	F	P	V	R	W	S	P	P	E	V	L	M	Y	S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	G	L	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R
Template Known Secondary structure		T					G	G	G																													T	T	S			S	S	T	T												T	T
Template Predicted Secondary structure
Template SS confidence
		417	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.
		616	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	Y	R	P	H	L	A	S	E	R	V	Y	T	I	M	Y	S	C	W	H	E	K	A	D	E	R	P	S	F	K	I	L	L	S	N	I	L	D	V	M	D	E	E	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E	S	S
Template Known Secondary structure						T	T													T		S	S	G	G	G	S												T	S	S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		477	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520