Job Description P35991 Confidence 100.00% Date Wed Jul 10 14:27:18 BST 2013 Rank 6 Aligned Residues 421 % Identity 37% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:78.039 Y:73.570 Z:54.337

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		218	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.		.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Predicted Secondary structure																																									.
Query SS confidence																																									.
Query Sequence		K	V	V	A	L	Y	D	Y	M	P	M	N	A	N	D	L	Q	L	R	K	G	E	E	Y	F	I	L	E	E	S	N	L	P	W	W	R	A	R	D	.	K	N	G	Q	E	G	Y	I	P	S	N	Y	I	T	E	A	E	D	S	I
Query Conservation																																									.
Alig confidence																													.												.																	.
Template Conservation																													.																													.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	.	E	E	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	.	D	S	L
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T							.				T	T							T	T	T								G	G	G				T	.	T	S	G
Template Predicted Secondary structure																													.																													.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.		.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.		.	.	.
		277	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.		300	.	.	.	.	.	.	.	.	.		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.
Predicted Secondary structure																									.											.
Query SS confidence																									.											.
Query Sequence		E	M	Y	E	W	Y	S	K	H	M	T	R	S	Q	A	E	Q	L	L	K	Q	E	G	.	K	E	G	G	F	I	V	R	D	S	.	S	K	A	G	K	Y	T	V	S	V	F	A	K	S	T	G	E	P	Q	G	V	I	R	H	Y
Query Conservation																									.											.
Alig confidence																									.											.																			.
Template Conservation																																																							.
Template Sequence		E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	.	D	T	V	K	H	Y
Template Known Secondary structure		G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T											T	T	T		.
Template Predicted Secondary structure																																																							.
Template SS confidence
		119	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.		.	.	.	.	.	.
		335	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	V	C	S	T	P	Q	S	Q	Y	Y	L	A	E	K	H	L	F	S	T	I	P	E	L	I	N	Y	H	Q	H	N	S	A	G	L	I	S	R	L	K	Y	P	V	S	K	Q	N	K	N	A	P	S	T	A	G	L	G	Y	G	S
Query Conservation
Alig confidence																																																						.	.	.	.
Template Conservation																																																						.	.	.	.
Template Sequence		K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	W	.	.	.	.	E	K	D	A
Template Known Secondary structure				B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B											.	.	.	.		T	T
Template Predicted Secondary structure																																																						.	.	.	.
Template SS confidence
		178	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.					230	.	.	.
		395	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	G	Q	Y	D	V	A	I	K	M	I	R	E	G	S	M	S	E	D	E	F	I	E	E	A	K	V	M	M	N	L	S	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H
Template Known Secondary structure		S	B			G	G	G											T	T									T	T	T												S	S														T
Template Predicted Secondary structure
Template SS confidence
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.
		455	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.		490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.
Predicted Secondary structure																																					.
Query SS confidence																																					.
Query Sequence		E	K	L	V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	.	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E
Query Conservation																																					.
Alig confidence												.																									.
Template Conservation												.
Template Sequence		D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E
Template Known Secondary structure		T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G
Template Predicted Secondary structure												.
Template SS confidence
		294	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.
		514	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	L	S	R	Y	V	L	D	D	E	Y	T	S	S	V	G	S	K	F	P	V	R	W	S	P	P	E	V	L	M	Y	S	K
Query Conservation
Alig confidence																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S
Template Known Secondary structure			T	T				S			S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S
Template Predicted Secondary structure																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		353	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.
		574	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	G	L	R	L	Y	R	P	H	L	A	S	E	R	V	Y	T	I	M	Y	S	C
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C
Template Known Secondary structure																				T	T	T			S	S	T	T												T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		413	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.
		634	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	H	E	K	A	D	E	R	P	S	F	K	I	L	L	S	N	I	L	D	V	M	D	E	E	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E
Template Known Secondary structure		T		S	S	G	G	G	S												T	T	T	S		G	G
Template Predicted Secondary structure
Template SS confidence
		473	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.